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PUBMED FOR HANDHELDS

Journal Abstract Search


466 related items for PubMed ID: 18287102

  • 1. Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain.
    Runge S, Thøgersen H, Madsen K, Lau J, Rudolph R.
    J Biol Chem; 2008 Apr 25; 283(17):11340-7. PubMed ID: 18287102
    [Abstract] [Full Text] [Related]

  • 2. Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain.
    Runge S, Schimmer S, Oschmann J, Schiødt CB, Knudsen SM, Jeppesen CB, Madsen K, Lau J, Thøgersen H, Rudolph R.
    Biochemistry; 2007 May 15; 46(19):5830-40. PubMed ID: 17444618
    [Abstract] [Full Text] [Related]

  • 3. Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain.
    West GM, Willard FS, Sloop KW, Showalter AD, Pascal BD, Griffin PR.
    PLoS One; 2014 May 15; 9(9):e105683. PubMed ID: 25180755
    [Abstract] [Full Text] [Related]

  • 4. Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
    Coopman K, Wallis R, Robb G, Brown AJ, Wilkinson GF, Timms D, Willars GB.
    Mol Endocrinol; 2011 Oct 15; 25(10):1804-18. PubMed ID: 21868452
    [Abstract] [Full Text] [Related]

  • 5. The major determinant of exendin-4/glucagon-like peptide 1 differential affinity at the rat glucagon-like peptide 1 receptor N-terminal domain is a hydrogen bond from SER-32 of exendin-4.
    Mann RJ, Nasr NE, Sinfield JK, Paci E, Donnelly D.
    Br J Pharmacol; 2010 Aug 15; 160(8):1973-84. PubMed ID: 20649595
    [Abstract] [Full Text] [Related]

  • 6. Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor.
    Underwood CR, Garibay P, Knudsen LB, Hastrup S, Peters GH, Rudolph R, Reedtz-Runge S.
    J Biol Chem; 2010 Jan 01; 285(1):723-30. PubMed ID: 19861722
    [Abstract] [Full Text] [Related]

  • 7. The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1.
    López de Maturana R, Willshaw A, Kuntzsch A, Rudolph R, Donnelly D.
    J Biol Chem; 2003 Mar 21; 278(12):10195-200. PubMed ID: 12524435
    [Abstract] [Full Text] [Related]

  • 8. A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors.
    Al-Sabah S, Donnelly D.
    Br J Pharmacol; 2003 Sep 21; 140(2):339-46. PubMed ID: 12970080
    [Abstract] [Full Text] [Related]

  • 9. Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R).
    Koole C, Reynolds CA, Mobarec JC, Hick C, Sexton PM, Sakmar TP.
    J Biol Chem; 2017 Apr 28; 292(17):7131-7144. PubMed ID: 28283573
    [Abstract] [Full Text] [Related]

  • 10. Recombinant expression, in vitro refolding, and biophysical characterization of the human glucagon-like peptide-1 receptor.
    Schröder-Tittmann K, Bosse-Doenecke E, Reedtz-Runge S, Ihling C, Sinz A, Tittmann K, Rudolph R.
    Biochemistry; 2010 Sep 14; 49(36):7956-65. PubMed ID: 20690636
    [Abstract] [Full Text] [Related]

  • 11. Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states.
    Neidigh JW, Fesinmeyer RM, Prickett KS, Andersen NH.
    Biochemistry; 2001 Nov 06; 40(44):13188-200. PubMed ID: 11683627
    [Abstract] [Full Text] [Related]

  • 12. The primary ligand-binding interaction at the GLP-1 receptor is via the putative helix of the peptide agonists.
    Al-Sabah S, Donnelly D.
    Protein Pept Lett; 2004 Feb 06; 11(1):9-14. PubMed ID: 14965273
    [Abstract] [Full Text] [Related]

  • 13. High potency antagonists of the pancreatic glucagon-like peptide-1 receptor.
    Montrose-Rafizadeh C, Yang H, Rodgers BD, Beday A, Pritchette LA, Eng J.
    J Biol Chem; 1997 Aug 22; 272(34):21201-6. PubMed ID: 9261127
    [Abstract] [Full Text] [Related]

  • 14. Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro.
    Swedberg JE, Schroeder CI, Mitchell JM, Fairlie DP, Edmonds DJ, Griffith DA, Ruggeri RB, Derksen DR, Loria PM, Price DA, Liras S, Craik DJ.
    J Biol Chem; 2016 Jul 22; 291(30):15778-87. PubMed ID: 27226591
    [Abstract] [Full Text] [Related]

  • 15. The amino terminal domain of the glucagon-like peptide-1 receptor is a critical determinant of subtype specificity.
    Graziano MP, Hey PJ, Strader CD.
    Recept Channels; 1996 Jul 22; 4(1):9-17. PubMed ID: 8723643
    [Abstract] [Full Text] [Related]

  • 16. α-Helix or β-Turn? An Investigation into N-Terminally Constrained Analogues of Glucagon-like Peptide 1 (GLP-1) and Exendin-4.
    Oddo A, Mortensen S, Thøgersen H, De Maria L, Hennen S, McGuire JN, Kofoed J, Linderoth L, Reedtz-Runge S.
    Biochemistry; 2018 Jul 17; 57(28):4148-4154. PubMed ID: 29877701
    [Abstract] [Full Text] [Related]

  • 17. [Conserved W52 led to reduced binding of glucogan-like peptide 1 receptor].
    Gao W, Wang J.
    Sheng Wu Gong Cheng Xue Bao; 2013 Jan 17; 29(1):87-94. PubMed ID: 23631121
    [Abstract] [Full Text] [Related]

  • 18. A small molecule ligand of the glucagon-like peptide 1 receptor targets its amino-terminal hormone binding domain.
    Tibaduiza EC, Chen C, Beinborn M.
    J Biol Chem; 2001 Oct 12; 276(41):37787-93. PubMed ID: 11498540
    [Abstract] [Full Text] [Related]

  • 19. Design and preparation of the class B G protein-coupled receptors GLP-1R and GCGR for 19 F-NMR studies in solution.
    Wang H, Hu W, Liu D, Wüthrich K.
    FEBS J; 2021 Jul 12; 288(13):4053-4063. PubMed ID: 33369025
    [Abstract] [Full Text] [Related]

  • 20. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) differentially regulates orthosteric but not allosteric agonist binding and function.
    Koole C, Wootten D, Simms J, Savage EE, Miller LJ, Christopoulos A, Sexton PM.
    J Biol Chem; 2012 Feb 03; 287(6):3659-73. PubMed ID: 22147709
    [Abstract] [Full Text] [Related]


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