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385 related items for PubMed ID: 18292931

  • 1. YM753, a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model.
    Shindoh N, Mori M, Terada Y, Oda K, Amino N, Kita A, Taniguchi M, Sohda KY, Nagai K, Sowa Y, Masuoka Y, Orita M, Sasamata M, Matsushime H, Furuichi K, Sakai T.
    Int J Oncol; 2008 Mar; 32(3):545-55. PubMed ID: 18292931
    [Abstract] [Full Text] [Related]

  • 2. Sulfonamide anilides, a novel class of histone deacetylase inhibitors, are antiproliferative against human tumors.
    Fournel M, Trachy-Bourget MC, Yan PT, Kalita A, Bonfils C, Beaulieu C, Frechette S, Leit S, Abou-Khalil E, Woo SH, Delorme D, MacLeod AR, Besterman JM, Li Z.
    Cancer Res; 2002 Aug 01; 62(15):4325-30. PubMed ID: 12154036
    [Abstract] [Full Text] [Related]

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  • 4. Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity.
    Komatsu Y, Tomizaki KY, Tsukamoto M, Kato T, Nishino N, Sato S, Yamori T, Tsuruo T, Furumai R, Yoshida M, Horinouchi S, Hayashi H.
    Cancer Res; 2001 Jun 01; 61(11):4459-66. PubMed ID: 11389076
    [Abstract] [Full Text] [Related]

  • 5. Enhanced pharmacodynamic and antitumor properties of a histone deacetylase inhibitor encapsulated in liposomes or ErbB2-targeted immunoliposomes.
    Drummond DC, Marx C, Guo Z, Scott G, Noble C, Wang D, Pallavicini M, Kirpotin DB, Benz CC.
    Clin Cancer Res; 2005 May 01; 11(9):3392-401. PubMed ID: 15867240
    [Abstract] [Full Text] [Related]

  • 6. Statins increase p21 through inhibition of histone deacetylase activity and release of promoter-associated HDAC1/2.
    Lin YC, Lin JH, Chou CW, Chang YF, Yeh SH, Chen CC.
    Cancer Res; 2008 Apr 01; 68(7):2375-83. PubMed ID: 18381445
    [Abstract] [Full Text] [Related]

  • 7. Apoptosis and tumor remission in liver tumor xenografts by 4-phenylbutyrate.
    Svechnikova I, Gray SG, Kundrotiene J, Ponthan F, Kogner P, Ekström TJ.
    Int J Oncol; 2003 Mar 01; 22(3):579-88. PubMed ID: 12579311
    [Abstract] [Full Text] [Related]

  • 8. Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor.
    Payne JE, Bonnefous C, Hassig CA, Symons KT, Guo X, Nguyen PM, Annable T, Wash PL, Hoffman TZ, Rao TS, Shiau AK, Malecha JW, Noble SA, Hager JH, Smith ND.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6093-6. PubMed ID: 18954983
    [Abstract] [Full Text] [Related]

  • 9. Anti-tumor activity of N-hydroxy-7-(2-naphthylthio) heptanomide, a novel histone deacetylase inhibitor.
    Kim DH, Lee J, Kim KN, Kim HJ, Jeung HC, Chung HC, Kwon HJ.
    Biochem Biophys Res Commun; 2007 Apr 27; 356(1):233-8. PubMed ID: 17353008
    [Abstract] [Full Text] [Related]

  • 10. MS-27-275, an inhibitor of histone deacetylase, has marked in vitro and in vivo antitumor activity against pediatric solid tumors.
    Jaboin J, Wild J, Hamidi H, Khanna C, Kim CJ, Robey R, Bates SE, Thiele CJ.
    Cancer Res; 2002 Nov 01; 62(21):6108-15. PubMed ID: 12414635
    [Abstract] [Full Text] [Related]

  • 11. Evaluation of the antitumor efficacy, pharmacokinetics, and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo.
    Graham C, Tucker C, Creech J, Favours E, Billups CA, Liu T, Fouladi M, Freeman BB, Stewart CF, Houghton PJ.
    Clin Cancer Res; 2006 Jan 01; 12(1):223-34. PubMed ID: 16397046
    [Abstract] [Full Text] [Related]

  • 12. Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin.
    Han JW, Ahn SH, Park SH, Wang SY, Bae GU, Seo DW, Kwon HK, Hong S, Lee HY, Lee YW, Lee HW.
    Cancer Res; 2000 Nov 01; 60(21):6068-74. PubMed ID: 11085529
    [Abstract] [Full Text] [Related]

  • 13. SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma.
    Lai JP, Yu C, Moser CD, Aderca I, Han T, Garvey TD, Murphy LM, Garrity-Park MM, Shridhar V, Adjei AA, Roberts LR.
    Gastroenterology; 2006 Jun 01; 130(7):2130-44. PubMed ID: 16762634
    [Abstract] [Full Text] [Related]

  • 14. Potent in vivo anti-breast cancer activity of IN-2001, a novel inhibitor of histone deacetylase, in MMTV/c-Neu mice.
    Joung KE, Min KN, An JY, Kim DK, Kong G, Sheen YY.
    Cancer Res; 2006 May 15; 66(10):5394-402. PubMed ID: 16707467
    [Abstract] [Full Text] [Related]

  • 15. Anti-tumor effect of apicidin on Ishikawa human endometrial cancer cells both in vitro and in vivo by blocking histone deacetylase 3 and 4.
    Ahn MY, Chung HY, Choi WS, Lee BM, Yoon S, Kim HS.
    Int J Oncol; 2010 Jan 15; 36(1):125-31. PubMed ID: 19956841
    [Abstract] [Full Text] [Related]

  • 16. Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models.
    Qian DZ, Wei YF, Wang X, Kato Y, Cheng L, Pili R.
    Prostate; 2007 Aug 01; 67(11):1182-93. PubMed ID: 17520666
    [Abstract] [Full Text] [Related]

  • 17. Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation.
    Camphausen K, Scott T, Sproull M, Tofilon PJ.
    Clin Cancer Res; 2004 Sep 15; 10(18 Pt 1):6066-71. PubMed ID: 15447991
    [Abstract] [Full Text] [Related]

  • 18. Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model.
    Attenni B, Ontoria JM, Cruz JC, Rowley M, Schultz-Fademrecht C, Steinkühler C, Jones P.
    Bioorg Med Chem Lett; 2009 Jun 01; 19(11):3081-4. PubMed ID: 19410459
    [Abstract] [Full Text] [Related]

  • 19. A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.
    Jones P, Altamura S, De Francesco R, Paz OG, Kinzel O, Mesiti G, Monteagudo E, Pescatore G, Rowley M, Verdirame M, Steinkühler C.
    J Med Chem; 2008 Apr 24; 51(8):2350-3. PubMed ID: 18370373
    [Abstract] [Full Text] [Related]

  • 20. Identification of (1H)-pyrroles as histone deacetylase inhibitors with antitumoral activity.
    Zubia A, Ropero S, Otaegui D, Ballestar E, Fraga MF, Boix-Chornet M, Berdasco M, Martinez A, Coll-Mulet L, Gil J, Cossío FP, Esteller M.
    Oncogene; 2009 Mar 19; 28(11):1477-84. PubMed ID: 19169274
    [Abstract] [Full Text] [Related]


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