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Journal Abstract Search

223 related items for PubMed ID: 18305400

  • 1. Nur77 upregulates HIF-alpha by inhibiting pVHL-mediated degradation.
    Kim BY, Kim H, Cho EJ, Youn HD.
    Exp Mol Med; 2008 Feb 29; 40(1):71-83. PubMed ID: 18305400
    [Abstract] [Full Text] [Related]

  • 2. Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma.
    Choi JW, Park SC, Kang GH, Liu JO, Youn HD.
    Cancer Res; 2004 Jan 01; 64(1):35-9. PubMed ID: 14729605
    [Abstract] [Full Text] [Related]

  • 3. Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha.
    Yoo YG, Yeo MG, Kim DK, Park H, Lee MO.
    J Biol Chem; 2004 Dec 17; 279(51):53365-73. PubMed ID: 15385570
    [Abstract] [Full Text] [Related]

  • 4. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.
    Clifford SC, Cockman ME, Smallwood AC, Mole DR, Woodward ER, Maxwell PH, Ratcliffe PJ, Maher ER.
    Hum Mol Genet; 2001 May 01; 10(10):1029-38. PubMed ID: 11331613
    [Abstract] [Full Text] [Related]

  • 5. STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.
    Jung JE, Kim HS, Lee CS, Shin YJ, Kim YN, Kang GH, Kim TY, Juhnn YS, Kim SJ, Park JW, Ye SK, Chung MH.
    Exp Mol Med; 2008 Oct 31; 40(5):479-85. PubMed ID: 18985005
    [Abstract] [Full Text] [Related]

  • 6. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS, Lee SJ, Yoon MH, Ha NC, Park BJ.
    Cell Cycle; 2012 Dec 01; 11(23):4462-73. PubMed ID: 23159849
    [Abstract] [Full Text] [Related]

  • 7. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
    Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER.
    Oncogene; 2001 Aug 16; 20(36):5067-74. PubMed ID: 11526493
    [Abstract] [Full Text] [Related]

  • 8. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
    Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH.
    J Biol Chem; 2000 Aug 18; 275(33):25733-41. PubMed ID: 10823831
    [Abstract] [Full Text] [Related]

  • 9. Role of Ran-regulated nuclear-cytoplasmic trafficking of pVHL in the regulation of microtubular stability-mediated HIF-1α in hypoxic cardiomyocytes.
    Jiang X, Zhang D, Zhang H, Huang Y, Teng M.
    Sci Rep; 2015 Mar 17; 5():9193. PubMed ID: 25779090
    [Abstract] [Full Text] [Related]

  • 10. 6-Mercaptopurine, an activator of Nur77, enhances transcriptional activity of HIF-1alpha resulting in new vessel formation.
    Yoo YG, Na TY, Yang WK, Kim HJ, Lee IK, Kong G, Chung JH, Lee MO.
    Oncogene; 2007 May 31; 26(26):3823-34. PubMed ID: 17146432
    [Abstract] [Full Text] [Related]

  • 11. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product.
    Pereira T, Zheng X, Ruas JL, Tanimoto K, Poellinger L.
    J Biol Chem; 2003 Feb 28; 278(9):6816-23. PubMed ID: 12468553
    [Abstract] [Full Text] [Related]

  • 12. Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha.
    Yuan Y, Hilliard G, Ferguson T, Millhorn DE.
    J Biol Chem; 2003 May 02; 278(18):15911-6. PubMed ID: 12606543
    [Abstract] [Full Text] [Related]

  • 13. The VHL protein recruits a novel KRAB-A domain protein to repress HIF-1alpha transcriptional activity.
    Li Z, Wang D, Na X, Schoen SR, Messing EM, Wu G.
    EMBO J; 2003 Apr 15; 22(8):1857-67. PubMed ID: 12682018
    [Abstract] [Full Text] [Related]

  • 14. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
    Hansen WJ, Ohh M, Moslehi J, Kondo K, Kaelin WG, Welch WJ.
    Mol Cell Biol; 2002 Mar 15; 22(6):1947-60. PubMed ID: 11865071
    [Abstract] [Full Text] [Related]

  • 15. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
    Qian H, Zou Y, Tang Y, Gong Y, Qian Z, Wei G, Zhang Q.
    Phys Chem Chem Phys; 2018 Jul 11; 20(27):18756-18765. PubMed ID: 29961792
    [Abstract] [Full Text] [Related]

  • 16. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
    Miller F, Kentsis A, Osman R, Pan ZQ.
    J Biol Chem; 2005 Mar 04; 280(9):7985-96. PubMed ID: 15611064
    [Abstract] [Full Text] [Related]

  • 17. Runx2 protein stabilizes hypoxia-inducible factor-1α through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes.
    Lee SH, Che X, Jeong JH, Choi JY, Lee YJ, Lee YH, Bae SC, Lee YM.
    J Biol Chem; 2012 Apr 27; 287(18):14760-71. PubMed ID: 22351759
    [Abstract] [Full Text] [Related]

  • 18. Post-translational control of Nur77.
    Wingate AD, Arthur JS.
    Biochem Soc Trans; 2006 Dec 27; 34(Pt 6):1107-9. PubMed ID: 17073761
    [Abstract] [Full Text] [Related]

  • 19. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.
    Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, Liu JO, Semenza GL.
    J Biol Chem; 2007 Dec 21; 282(51):37064-73. PubMed ID: 17965024
    [Abstract] [Full Text] [Related]

  • 20. CR6-interacting factor 1 interacts with orphan nuclear receptor Nur77 and inhibits its transactivation.
    Park KC, Song KH, Chung HK, Kim H, Kim DW, Song JH, Hwang ES, Jung HS, Park SH, Bae I, Lee IK, Choi HS, Shong M.
    Mol Endocrinol; 2005 Jan 21; 19(1):12-24. PubMed ID: 15459248
    [Abstract] [Full Text] [Related]

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