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Journal Abstract Search

319 related items for PubMed ID: 18321244

  • 1. Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
    Ekerot M, Stavridis MP, Delavaine L, Mitchell MP, Staples C, Owens DM, Keenan ID, Dickinson RJ, Storey KG, Keyse SM.
    Biochem J; 2008 Jun 01; 412(2):287-98. PubMed ID: 18321244
    [Abstract] [Full Text] [Related]

  • 2. DUSP6/MKP-3 inactivates ERK1/2 but fails to bind and inactivate ERK5.
    Arkell RS, Dickinson RJ, Squires M, Hayat S, Keyse SM, Cook SJ.
    Cell Signal; 2008 May 01; 20(5):836-43. PubMed ID: 18280112
    [Abstract] [Full Text] [Related]

  • 3. Feedback regulation of DUSP6 transcription responding to MAPK1 via ETS2 in human cells.
    Furukawa T, Tanji E, Xu S, Horii A.
    Biochem Biophys Res Commun; 2008 Dec 05; 377(1):317-20. PubMed ID: 18848526
    [Abstract] [Full Text] [Related]

  • 4. Fibroblast growth factor receptor signaling activates the human interstitial collagenase promoter via the bipartite Ets-AP1 element.
    Newberry EP, Willis D, Latifi T, Boudreaux JM, Towler DA.
    Mol Endocrinol; 1997 Jul 05; 11(8):1129-44. PubMed ID: 9212060
    [Abstract] [Full Text] [Related]

  • 5. Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation.
    Marchetti S, Gimond C, Chambard JC, Touboul T, Roux D, Pouysségur J, Pagès G.
    Mol Cell Biol; 2005 Jan 05; 25(2):854-64. PubMed ID: 15632084
    [Abstract] [Full Text] [Related]

  • 6. Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development.
    Znosko WA, Yu S, Thomas K, Molina GA, Li C, Tsang W, Dawid IB, Moon AM, Tsang M.
    Dev Biol; 2010 Jun 01; 342(1):11-25. PubMed ID: 20346941
    [Abstract] [Full Text] [Related]

  • 7. Dual-specificity phosphatase 6 (Dusp6), a negative regulator of FGF2/ERK1/2 signaling, enhances 17β-estradiol-induced cell growth in endometrial adenocarcinoma cell.
    Zhang H, Guo Q, Wang C, Yan L, Fu Y, Fan M, Zhao X, Li M.
    Mol Cell Endocrinol; 2013 Aug 25; 376(1-2):60-9. PubMed ID: 23419500
    [Abstract] [Full Text] [Related]

  • 8. Dusp6 (Mkp3) is a negative feedback regulator of FGF-stimulated ERK signaling during mouse development.
    Li C, Scott DA, Hatch E, Tian X, Mansour SL.
    Development; 2007 Jan 25; 134(1):167-76. PubMed ID: 17164422
    [Abstract] [Full Text] [Related]

  • 9. Differential expression profiles and roles of inducible DUSPs and ERK1/2-specific constitutive DUSP6 and DUSP7 in microglia.
    Ham JE, Oh EK, Kim DH, Choi SH.
    Biochem Biophys Res Commun; 2015 Nov 13; 467(2):254-60. PubMed ID: 26435497
    [Abstract] [Full Text] [Related]

  • 10. Post-transcriptional regulation of the DUSP6/MKP-3 phosphatase by MEK/ERK signaling and hypoxia.
    Bermudez O, Jouandin P, Rottier J, Bourcier C, Pagès G, Gimond C.
    J Cell Physiol; 2011 Jan 13; 226(1):276-84. PubMed ID: 20665674
    [Abstract] [Full Text] [Related]

  • 11. ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells.
    Sarközi R, Miller B, Pollack V, Feifel E, Mayer G, Sorokin A, Schramek H.
    J Cell Physiol; 2007 Apr 13; 211(1):88-100. PubMed ID: 17131384
    [Abstract] [Full Text] [Related]

  • 12. DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility.
    Maillet M, Purcell NH, Sargent MA, York AJ, Bueno OF, Molkentin JD.
    J Biol Chem; 2008 Nov 07; 283(45):31246-55. PubMed ID: 18753132
    [Abstract] [Full Text] [Related]

  • 13. A spatial and temporal map of FGF/Erk1/2 activity and response repertoires in the early chick embryo.
    Lunn JS, Fishwick KJ, Halley PA, Storey KG.
    Dev Biol; 2007 Feb 15; 302(2):536-52. PubMed ID: 17123506
    [Abstract] [Full Text] [Related]

  • 14. Caspase-3 cleavage of DUSP6/MKP3 at the interdomain region generates active MKP3 fragments that regulate ERK1/2 subcellular localization and function.
    Cejudo-Marín R, Tárrega C, Nunes-Xavier CE, Pulido R.
    J Mol Biol; 2012 Jun 29; 420(1-2):128-38. PubMed ID: 22504224
    [Abstract] [Full Text] [Related]

  • 15. Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.
    Zhang Z, Kobayashi S, Borczuk AC, Leidner RS, Laframboise T, Levine AD, Halmos B.
    Carcinogenesis; 2010 Apr 29; 31(4):577-86. PubMed ID: 20097731
    [Abstract] [Full Text] [Related]

  • 16. Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3.
    Nichols A, Camps M, Gillieron C, Chabert C, Brunet A, Wilsbacher J, Cobb M, Pouyssegur J, Shaw JP, Arkinstall S.
    J Biol Chem; 2000 Aug 11; 275(32):24613-21. PubMed ID: 10811804
    [Abstract] [Full Text] [Related]

  • 17. Cooperation of ERK and SCFSkp2 for MKP-1 destruction provides a positive feedback regulation of proliferating signaling.
    Lin YW, Yang JL.
    J Biol Chem; 2006 Jan 13; 281(2):915-26. PubMed ID: 16286470
    [Abstract] [Full Text] [Related]

  • 18. Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1.
    Slack DN, Seternes OM, Gabrielsen M, Keyse SM.
    J Biol Chem; 2001 May 11; 276(19):16491-500. PubMed ID: 11278799
    [Abstract] [Full Text] [Related]

  • 19. Negative feedback regulation of FGF signaling levels by Pyst1/MKP3 in chick embryos.
    Eblaghie MC, Lunn JS, Dickinson RJ, Münsterberg AE, Sanz-Ezquerro JJ, Farrell ER, Mathers J, Keyse SM, Storey K, Tickle C.
    Curr Biol; 2003 Jun 17; 13(12):1009-18. PubMed ID: 12814546
    [Abstract] [Full Text] [Related]

  • 20. Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity.
    Liu R, Peters M, Urban N, Knowlton J, Napierala T, Gabrysiak J.
    Biochem Biophys Res Commun; 2020 Nov 26; 533(1):17-22. PubMed ID: 32917360
    [Abstract] [Full Text] [Related]

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