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Journal Abstract Search

361 related items for PubMed ID: 18325637

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  • 3. Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group.
    Carrión MD, Chayah M, Entrena A, López A, Gallo MA, Acuña-Castroviejo D, Camacho ME.
    Bioorg Med Chem; 2013 Jul 15; 21(14):4132-42. PubMed ID: 23735830
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  • 4. 1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence.
    López-Cara LC, Carrión MD, Entrena A, Gallo MA, Espinosa A, López A, Escames G, Acuña-Castroviejo D, Camacho ME.
    Eur J Med Chem; 2012 Apr 15; 50():129-39. PubMed ID: 22336385
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  • 5. Discovery of a series of aminopiperidines as novel iNOS inhibitors.
    Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):336-43. PubMed ID: 18024030
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  • 6. 4,5-dihydro-1H-pyrazole derivatives with inhibitory nNOS activity in rat brain: synthesis and structure-activity relationships.
    Camacho ME, León J, Entrena A, Velasco G, Carrión MD, Escames G, Vivó A, Acuña-Castroviejo D, Gallo MA, Espinosa A.
    J Med Chem; 2004 Nov 04; 47(23):5641-50. PubMed ID: 15509163
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  • 7. Kynurenamines as neural nitric oxide synthase inhibitors.
    Entrena A, Camacho ME, Carrión MD, López-Cara LC, Velasco G, León J, Escames G, Acuña-Castroviejo D, Tapias V, Gallo MA, Vivó A, Espinosa A.
    J Med Chem; 2005 Dec 29; 48(26):8174-81. PubMed ID: 16366599
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  • 8. Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.
    Hah JM, Martásek P, Roman LJ, Silverman RB.
    J Med Chem; 2003 Apr 24; 46(9):1661-9. PubMed ID: 12699384
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  • 9. The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
    Strub A, Ulrich WR, Hesslinger C, Eltze M, Fuchss T, Strassner J, Strand S, Lehner MD, Boer R.
    Mol Pharmacol; 2006 Jan 24; 69(1):328-37. PubMed ID: 16223957
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  • 10. Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNOS dimerization inhibitors that are orally active in pain models.
    Payne JE, Bonnefous C, Symons KT, Nguyen PM, Sablad M, Rozenkrants N, Zhang Y, Wang L, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND.
    J Med Chem; 2010 Nov 11; 53(21):7739-55. PubMed ID: 20931971
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  • 11. Intracerebroventricular injection of neuronal and inducible nitric oxide synthase inhibitors attenuates fever due to LPS in rats.
    Soszynski D, Chelminiak M.
    J Physiol Pharmacol; 2007 Sep 11; 58(3):551-61. PubMed ID: 17928650
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  • 12. Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors.
    Chayah M, Carrión MD, Gallo MA, Jiménez R, Duarte J, Camacho ME.
    ChemMedChem; 2015 May 11; 10(5):874-82. PubMed ID: 25801086
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  • 13. Intracerebroventricular injection of neuronal and inducible nitric oxide synthase inhibitors does not influence febrile response in rats during turpentine abscess.
    Soszynski D, Chelminiak M.
    J Physiol Pharmacol; 2007 Dec 11; 58(4):657-67. PubMed ID: 18195479
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  • 14. 1-(1,3-Benzodioxol-5-ylmethyl)-3-[4-(1H-imidazol-1-yl)phenoxy]-piperidine analogs as potent and selective inhibitors of nitric oxide formation.
    Wei RG, Adler M, Davey D, Ho E, Mohan R, Polokoff M, Tseng JL, Whitlow M, Xu W, Yuan S, Phillips G.
    Bioorg Med Chem Lett; 2007 May 01; 17(9):2499-504. PubMed ID: 17368901
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  • 15. Synthesis and biological evaluation of indazole derivatives.
    Claramunt RM, López C, López A, Pérez-Medina C, Pérez-Torralba M, Alkorta I, Elguero J, Escames G, Acuña-Castroviejo D.
    Eur J Med Chem; 2011 Apr 01; 46(4):1439-47. PubMed ID: 21334118
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  • 16. The effect of N-nitro-L-arginine and aminoguanidine treatment on changes in constitutive and inducible nitric oxide synthases in the spinal cord after sciatic nerve transection.
    Lukacova N, Davidova A, Kolesar D, Kolesarova M, Schreiberova A, Lackova M, Krizanova O, Marsala M, Marsala J.
    Int J Mol Med; 2008 Apr 01; 21(4):413-21. PubMed ID: 18360686
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  • 17. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL, Shearer BG, Oplinger JA, Lee S, Garvey EP, Salter M, Duffy C, Burnette TC, Furfine ES.
    J Med Chem; 1998 Jul 16; 41(15):2858-71. PubMed ID: 9667974
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  • 18. Molecular mechanism of emotional fever--the role of nitric oxide.
    Soszynski D.
    J Physiol Pharmacol; 2006 Nov 16; 57 Suppl 8():51-9. PubMed ID: 17242472
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  • 19. Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters.
    Silverman RB, Huang H, Marletta MA, Martasek P.
    J Med Chem; 1997 Aug 29; 40(18):2813-7. PubMed ID: 9288162
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  • 20. 4,5-dialkylsubstituted 2-imino-1,3-thiazolidine derivatives as potent inducible nitric oxide synthase inhibitors.
    Ueda S, Terauchi H, Yano A, Matsumoto M, Kubo T, Kyoya Y, Suzuki K, Ido M, Kawasaki M.
    Bioorg Med Chem; 2004 Aug 01; 12(15):4101-16. PubMed ID: 15246088
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