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Journal Abstract Search

193 related items for PubMed ID: 18328272

  • 1. Molecular diversity in the context of leadlikeness: compound properties that enable effective biochemical screening.
    Rishton GM.
    Curr Opin Chem Biol; 2008 Jun; 12(3):340-51. PubMed ID: 18328272
    [Abstract] [Full Text] [Related]

  • 2. Pursuing the leadlikeness concept in pharmaceutical research.
    Hann MM, Oprea TI.
    Curr Opin Chem Biol; 2004 Jun; 8(3):255-63. PubMed ID: 15183323
    [Abstract] [Full Text] [Related]

  • 3. Fragment-based activity space: smaller is better.
    Hesterkamp T, Whittaker M.
    Curr Opin Chem Biol; 2008 Jun; 12(3):260-8. PubMed ID: 18316043
    [Abstract] [Full Text] [Related]

  • 4. ChemGPS-NP: tuned for navigation in biologically relevant chemical space.
    Larsson J, Gottfries J, Muresan S, Backlund A.
    J Nat Prod; 2007 May; 70(5):789-94. PubMed ID: 17439280
    [Abstract] [Full Text] [Related]

  • 5. Nonleadlikeness and leadlikeness in biochemical screening.
    Rishton GM.
    Drug Discov Today; 2003 Jan 15; 8(2):86-96. PubMed ID: 12565011
    [Abstract] [Full Text] [Related]

  • 6. Structure-based pharmacophore screening for natural-product-derived PPARgamma agonists.
    Tanrikulu Y, Rau O, Schwarz O, Proschak E, Siems K, Müller-Kuhrt L, Schubert-Zsilavecz M, Schneider G.
    Chembiochem; 2009 Jan 05; 10(1):75-8. PubMed ID: 19067454
    [No Abstract] [Full Text] [Related]

  • 7. A review of high throughput technology for the screening of natural products.
    Mishra KP, Ganju L, Sairam M, Banerjee PK, Sawhney RC.
    Biomed Pharmacother; 2008 Feb 05; 62(2):94-8. PubMed ID: 17692498
    [Abstract] [Full Text] [Related]

  • 8. Observations on screening-based research and some concerning trends in the literature.
    Baell JB.
    Future Med Chem; 2010 Oct 05; 2(10):1529-46. PubMed ID: 21426147
    [Abstract] [Full Text] [Related]

  • 9. Plant natural products: back to the future or into extinction?
    McChesney JD, Venkataraman SK, Henri JT.
    Phytochemistry; 2007 Jul 05; 68(14):2015-22. PubMed ID: 17574638
    [Abstract] [Full Text] [Related]

  • 10. [High content drug screening and its application].
    Zhang L, Du GH.
    Yao Xue Xue Bao; 2005 Jun 05; 40(6):486-90. PubMed ID: 16144310
    [No Abstract] [Full Text] [Related]

  • 11. The impact of natural products upon modern drug discovery.
    Ganesan A.
    Curr Opin Chem Biol; 2008 Jun 05; 12(3):306-17. PubMed ID: 18423384
    [Abstract] [Full Text] [Related]

  • 12. Fragonomics: fragment-based drug discovery.
    Zartler ER, Shapiro MJ.
    Curr Opin Chem Biol; 2005 Aug 05; 9(4):366-70. PubMed ID: 15925537
    [Abstract] [Full Text] [Related]

  • 13. The evolution of microarrayed compound screening.
    Hoever M, Zbinden P.
    Drug Discov Today; 2004 Apr 15; 9(8):358-65. PubMed ID: 15081963
    [Abstract] [Full Text] [Related]

  • 14. High throughput solubility determination with application to selection of compounds for fragment screening.
    Colclough N, Hunter A, Kenny PW, Kittlety RS, Lobedan L, Tam KY, Timms MA.
    Bioorg Med Chem; 2008 Jul 01; 16(13):6611-6. PubMed ID: 18502135
    [Abstract] [Full Text] [Related]

  • 15. Targets looking for drugs: a multistep computational protocol for the development of structure-based pharmacophores and their applications for hit discovery.
    Tintori C, Corradi V, Magnani M, Manetti F, Botta M.
    J Chem Inf Model; 2008 Nov 01; 48(11):2166-79. PubMed ID: 18942779
    [Abstract] [Full Text] [Related]

  • 16. Cell-based high-content screening of small-molecule libraries.
    Korn K, Krausz E.
    Curr Opin Chem Biol; 2007 Oct 01; 11(5):503-10. PubMed ID: 17931958
    [Abstract] [Full Text] [Related]

  • 17. Novel method for generating structure-based pharmacophores using energetic analysis.
    Salam NK, Nuti R, Sherman W.
    J Chem Inf Model; 2009 Oct 01; 49(10):2356-68. PubMed ID: 19761201
    [Abstract] [Full Text] [Related]

  • 18. Fragments, network biology and designing multiple ligands.
    Morphy R, Rankovic Z.
    Drug Discov Today; 2007 Feb 01; 12(3-4):156-60. PubMed ID: 17275736
    [Abstract] [Full Text] [Related]

  • 19. In silico fragment screening by replica generation (FSRG) method for fragment-based drug design.
    Fukunishi Y, Mashimo T, Orita M, Ohno K, Nakamura H.
    J Chem Inf Model; 2009 Apr 01; 49(4):925-33. PubMed ID: 19354203
    [Abstract] [Full Text] [Related]

  • 20. Leadlikeness and structural diversity of synthetic screening libraries.
    Verheij HJ.
    Mol Divers; 2006 Aug 01; 10(3):377-88. PubMed ID: 17031539
    [Abstract] [Full Text] [Related]

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