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Journal Abstract Search
393 related items for PubMed ID: 18337127
1. Validation of a larval zebrafish locomotor assay for assessing the seizure liability of early-stage development drugs. Winter MJ, Redfern WS, Hayfield AJ, Owen SF, Valentin JP, Hutchinson TH. J Pharmacol Toxicol Methods; 2008; 57(3):176-87. PubMed ID: 18337127 [Abstract] [Full Text] [Related]
2. Validation of the use of zebrafish larvae in visual safety assessment. Richards FM, Alderton WK, Kimber GM, Liu Z, Strang I, Redfern WS, Valentin JP, Winter MJ, Hutchinson TH. J Pharmacol Toxicol Methods; 2008; 58(1):50-8. PubMed ID: 18541443 [Abstract] [Full Text] [Related]
3. Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability. Easter A, Sharp TH, Valentin JP, Pollard CE. J Pharmacol Toxicol Methods; 2007; 56(2):223-33. PubMed ID: 17600733 [Abstract] [Full Text] [Related]
5. Rapid and accurate assessment of seizure liability of drugs by using an optimal support vector machine method. Zhang H, Li W, Xie Y, Wang WJ, Li LL, Yang SY. Toxicol In Vitro; 2011 Dec; 25(8):1848-54. PubMed ID: 21641989 [Abstract] [Full Text] [Related]
6. A multi-endpoint in vivo larval zebrafish (Danio rerio) model for the assessment of integrated cardiovascular function. Parker T, Libourel PA, Hetheridge MJ, Cumming RI, Sutcliffe TP, Goonesinghe AC, Ball JS, Owen SF, Chomis Y, Winter MJ. J Pharmacol Toxicol Methods; 2014 Dec; 69(1):30-8. PubMed ID: 24140389 [Abstract] [Full Text] [Related]
7. Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery. Berghmans S, Butler P, Goldsmith P, Waldron G, Gardner I, Golder Z, Richards FM, Kimber G, Roach A, Alderton W, Fleming A. J Pharmacol Toxicol Methods; 2008 Dec; 58(1):59-68. PubMed ID: 18585469 [Abstract] [Full Text] [Related]
9. Establishment of a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish. Koseki N, Deguchi J, Yamashita A, Miyawaki I, Funabashi H. J Toxicol Sci; 2014 Aug; 39(4):579-600. PubMed ID: 25056783 [Abstract] [Full Text] [Related]
10. Set-up of an infrared fast behavioral assay using zebrafish (Danio rerio) larvae, and its application in compound biotoxicity screening. Bichara D, Calcaterra NB, Arranz S, Armas P, Simonetta SH. J Appl Toxicol; 2014 Feb; 34(2):214-9. PubMed ID: 23401233 [Abstract] [Full Text] [Related]
13. Effects of picrotoxin on zebrafish larvae behaviors: A comparison study with PTZ. Yang X, Lin J, Peng X, Zhang Q, Zhang Y, Guo N, Zhou S, Li Q. Epilepsy Behav; 2017 May 17; 70(Pt A):224-231. PubMed ID: 28437751 [Abstract] [Full Text] [Related]
15. A high-throughput method for predicting drug effects on gut transit time using larval zebrafish. Cassar S, Huang X, Cole T. J Pharmacol Toxicol Methods; 2015 May 17; 76():72-5. PubMed ID: 26311656 [Abstract] [Full Text] [Related]