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Journal Abstract Search

151 related items for PubMed ID: 18338842

  • 1. Amide-based prodrugs of spermidine-bridged dinuclear platinum. Synthesis, DNA binding, and biological activity.
    Hegmans A, Kasparkova J, Vrana O, Kelland LR, Brabec V, Farrell NP.
    J Med Chem; 2008 Apr 10; 51(7):2254-60. PubMed ID: 18338842
    [Abstract] [Full Text] [Related]

  • 2. Novel approaches to polynuclear platinum pro-drugs. Selective release of cytotoxic platinum-spermidine species through hydrolytic cleavage of carbamates.
    Hegmans A, Qu Y, Kelland LR, Roberts JD, Farrell N.
    Inorg Chem; 2001 Nov 19; 40(24):6108-14. PubMed ID: 11703107
    [Abstract] [Full Text] [Related]

  • 3. Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs.
    Shi H, Romero-Canelón I, Hreusova M, Novakova O, Venkatesh V, Habtemariam A, Clarkson GJ, Song JI, Brabec V, Sadler PJ.
    Inorg Chem; 2018 Nov 19; 57(22):14409-14420. PubMed ID: 30365308
    [Abstract] [Full Text] [Related]

  • 4. A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464.
    McGregor TD, Hegmans A, Kaspárková J, Neplechová K, Nováková O, Penazová H, Vrána O, Brabec V, Farrell N.
    J Biol Inorg Chem; 2002 Apr 19; 7(4-5):397-404. PubMed ID: 11941497
    [Abstract] [Full Text] [Related]

  • 5. Synthesis, characterization, activities, cell uptake and DNA binding of trinuclear complex: [{trans-PtCl(NH(3))}(2)mu-{trans-Pt(NH(3))(2-hydroxypyridine)-(H(2)N(CH(2))(6)NH(2))(2)]Cl(4).
    Cheng H, Huq F, Beale P, Fisher K.
    Eur J Med Chem; 2005 Aug 19; 40(8):772-81. PubMed ID: 16122580
    [Abstract] [Full Text] [Related]

  • 6. Platinum anticancer agents and antidepressants: desipramine enhances platinum-based cytotoxicity in human colon cancer cells.
    Kabolizadeh P, Engelmann BJ, Pullen N, Stewart JK, Ryan JJ, Farrell NP.
    J Biol Inorg Chem; 2012 Jan 19; 17(1):123-32. PubMed ID: 21918844
    [Abstract] [Full Text] [Related]

  • 7. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A, Berners-Price SJ, Davies MS, Thomas DS, Humphreys AS, Farrell N.
    J Am Chem Soc; 2004 Feb 25; 126(7):2166-80. PubMed ID: 14971952
    [Abstract] [Full Text] [Related]

  • 8. Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [(trans-PtCl(NH(3))(2))(2)(mu-trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2))](4+) (BBR3464).
    Davies MS, Thomas DS, Hegmans A, Berners-Price SJ, Farrell N.
    Inorg Chem; 2002 Mar 11; 41(5):1101-9. PubMed ID: 11874344
    [Abstract] [Full Text] [Related]

  • 9. The trans influence in the modulation of platinum anticancer agent biology: the effect of nitrite leaving group on aquation, reactions with S-nucleophiles and DNA binding of dinuclear and trinuclear compounds.
    Montero EI, Zhang J, Moniodis JJ, Berners-Price SJ, Farrell NP.
    Chemistry; 2010 Aug 09; 16(30):9175-85. PubMed ID: 20589847
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, characterization, and biological evaluation of new tetrazole-based platinum(II) and palladium(II) chlorido complexes--potent cisplatin analogues and their trans isomers.
    Serebryanskaya TV, Yung T, Bogdanov AA, Shchebet A, Johnsen SA, Lyakhov AS, Ivashkevich LS, Ibrahimava ZA, Garbuzenco TS, Kolesnikova TS, Melnova NI, Gaponik PN, Ivashkevich OA.
    J Inorg Biochem; 2013 Mar 09; 120():44-53. PubMed ID: 23305964
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of series of diazine-bridged dinuclear platinum(II) complexes through in vitro toxicity and molecular modeling: correlation between structure and activity of Pt(II) complexes.
    Senerovic L, Zivkovic MD, Veselinovic A, Pavic A, Djuran MI, Rajkovic S, Nikodinovic-Runic J.
    J Med Chem; 2015 Feb 12; 58(3):1442-51. PubMed ID: 25551180
    [Abstract] [Full Text] [Related]

  • 12. Neutral and ionic platinum compounds containing a cyclometallated chiral primary amine: synthesis, antitumor activity, DNA interaction and topoisomerase I-cathepsin B inhibition.
    Albert J, Bosque R, Crespo M, Granell J, López C, Martín R, González A, Jayaraman A, Quirante J, Calvis C, Badía J, Baldomà L, Font-Bardia M, Cascante M, Messeguer R.
    Dalton Trans; 2015 Aug 14; 44(30):13602-14. PubMed ID: 26140359
    [Abstract] [Full Text] [Related]

  • 13. A dual-targeting hybrid platinum(IV) prodrug for enhancing efficacy.
    Xiao H, Yan L, Zhang Y, Qi R, Li W, Wang R, Liu S, Huang Y, Li Y, Jing X.
    Chem Commun (Camb); 2012 Nov 11; 48(87):10730-2. PubMed ID: 23012698
    [Abstract] [Full Text] [Related]

  • 14. Reaction of polynuclear platinum antitumor compounds with reduced glutathione studied by multinuclear (1H, 1H-15N gradient heteronuclear single-quantum coherence, and 195Pt) NMR spectroscopy.
    Oehlsen ME, Qu Y, Farrell N.
    Inorg Chem; 2003 Sep 08; 42(18):5498-506. PubMed ID: 12950196
    [Abstract] [Full Text] [Related]

  • 15. A novel isomerization on interaction of antitumor-active azole-bridged dinuclear platinum(II) complexes with 9-ethylguanine. Platinum(II) atom migration from N2 to N3 on 1,2,3-triazole.
    Komeda S, Lutz M, Spek AL, Yamanaka Y, Sato T, Chikuma M, Reedijk J.
    J Am Chem Soc; 2002 May 01; 124(17):4738-46. PubMed ID: 11971723
    [Abstract] [Full Text] [Related]

  • 16. Comparison of cytotoxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine leukemia cell lines.
    Roberts JD, Peroutka J, Beggiolin G, Manzotti C, Piazzoni L, Farrell N.
    J Inorg Biochem; 1999 Oct 01; 77(1-2):47-50. PubMed ID: 10626353
    [Abstract] [Full Text] [Related]

  • 17. Novel oximato-bridged platinum(II) di- and trimer(s): synthetic, structural, and in vitro anticancer activity studies.
    Scaffidi-Domianello YY, Legin AA, Jakupec MA, Roller A, Kukushkin VY, Galanski MS, Keppler BK.
    Inorg Chem; 2012 Jul 02; 51(13):7153-63. PubMed ID: 22691006
    [Abstract] [Full Text] [Related]

  • 18. Coordination-driven self-assembly of a Pt(iv) prodrug-conjugated supramolecular hexagon.
    Yue Z, Wang H, Li Y, Qin Y, Xu L, Bowers DJ, Gangoda M, Li X, Yang HB, Zheng YR.
    Chem Commun (Camb); 2018 Jan 18; 54(7):731-734. PubMed ID: 29303526
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, cytotoxic activity and DNA interaction studies of new dinuclear platinum(ii) complexes with an aromatic 1,5-naphthyridine bridging ligand: DNA binding mode of polynuclear platinum(ii) complexes in relation to the complex structure.
    Konovalov B, Živković MD, Milovanović JZ, Djordjević DB, Arsenijević AN, Vasić IR, Janjić GV, Franich A, Manojlović D, Skrivanj S, Milovanović MZ, Djuran MI, Rajković S.
    Dalton Trans; 2018 Oct 30; 47(42):15091-15102. PubMed ID: 30303498
    [Abstract] [Full Text] [Related]

  • 20. Specific Conformational Change in Giant DNA Caused by Anticancer Tetrazolato-Bridged Dinuclear Platinum(II) Complexes: Middle-Length Alkyl Substituents Exhibit Minimum Effect.
    Komeda S, Yoneyama H, Uemura M, Muramatsu A, Okamoto N, Konishi H, Takahashi H, Takagi A, Fukuda W, Imanaka T, Kanbe T, Harusawa S, Yoshikawa Y, Yoshikawa K.
    Inorg Chem; 2017 Jan 17; 56(2):802-811. PubMed ID: 28045514
    [Abstract] [Full Text] [Related]

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