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807 related items for PubMed ID: 18339873

  • 1. Enzastaurin, a protein kinase C beta inhibitor, suppresses signaling through the ribosomal S6 kinase and bad pathways and induces apoptosis in human gastric cancer cells.
    Lee KW, Kim SG, Kim HP, Kwon E, You J, Choi HJ, Park JH, Kang BC, Im SA, Kim TY, Kim WH, Bang YJ.
    Cancer Res; 2008 Mar 15; 68(6):1916-26. PubMed ID: 18339873
    [Abstract] [Full Text] [Related]

  • 2. The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts.
    Graff JR, McNulty AM, Hanna KR, Konicek BW, Lynch RL, Bailey SN, Banks C, Capen A, Goode R, Lewis JE, Sams L, Huss KL, Campbell RM, Iversen PW, Neubauer BL, Brown TJ, Musib L, Geeganage S, Thornton D.
    Cancer Res; 2005 Aug 15; 65(16):7462-9. PubMed ID: 16103100
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  • 3. Prevention of TGF-beta-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways.
    Lin SJ, Chang C, Ng AK, Wang SH, Li JJ, Hu CP.
    Apoptosis; 2007 Sep 15; 12(9):1659-70. PubMed ID: 17624592
    [Abstract] [Full Text] [Related]

  • 4. Delta9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria.
    Jia W, Hegde VL, Singh NP, Sisco D, Grant S, Nagarkatti M, Nagarkatti PS.
    Mol Cancer Res; 2006 Aug 15; 4(8):549-62. PubMed ID: 16908594
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  • 5. Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.
    Lee DH, Szczepanski MJ, Lee YJ.
    J Cell Biochem; 2009 Apr 15; 106(6):1113-22. PubMed ID: 19229860
    [Abstract] [Full Text] [Related]

  • 6. Synergistic anti-tumor efficacy of lovastatin and protein kinase C-beta inhibitor in hepatocellular carcinoma.
    Kim W, Yoon JH, Kim JR, Jang IJ, Bang YJ, Kim YJ, Lee HS.
    Cancer Chemother Pharmacol; 2009 Aug 15; 64(3):497-507. PubMed ID: 19096848
    [Abstract] [Full Text] [Related]

  • 7. Combretastatin A4-induced differential cytotoxicity and reduced metastatic ability by inhibition of AKT function in human gastric cancer cells.
    Lin HL, Chiou SH, Wu CW, Lin WB, Chen LH, Yang YP, Tsai ML, Uen YH, Liou JP, Chi CW.
    J Pharmacol Exp Ther; 2007 Oct 15; 323(1):365-73. PubMed ID: 17646428
    [Abstract] [Full Text] [Related]

  • 8. Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.
    Estrada AC, Syrovets T, Pitterle K, Lunov O, Büchele B, Schimana-Pfeifer J, Schmidt T, Morad SA, Simmet T.
    Mol Pharmacol; 2010 Mar 15; 77(3):378-87. PubMed ID: 20018812
    [Abstract] [Full Text] [Related]

  • 9. Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation.
    Cho IR, Koh SS, Min HJ, Park EH, Srisuttee R, Jhun BH, Kang CD, Kim M, Johnston RN, Chung YH.
    Int J Oncol; 2010 Apr 15; 36(4):1023-30. PubMed ID: 20198349
    [Abstract] [Full Text] [Related]

  • 10. Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells.
    Xiao D, Singh SV.
    Carcinogenesis; 2006 Mar 15; 27(3):533-40. PubMed ID: 16169930
    [Abstract] [Full Text] [Related]

  • 11. Constitutively activated FLT3 phosphorylates BAD partially through pim-1.
    Kim KT, Levis M, Small D.
    Br J Haematol; 2006 Sep 15; 134(5):500-9. PubMed ID: 16869825
    [Abstract] [Full Text] [Related]

  • 12. Enhanced susceptibility to apoptosis of oral squamous cell carcinoma cells subjected to combined treatment with anticancer drugs and phosphatidylinositol 3-kinase inhibitors.
    Iwase M, Yoshiba S, Uchid M, Takaoka S, Kurihara Y, Ito D, Hatori M, Shintani S.
    Int J Oncol; 2007 Nov 15; 31(5):1141-7. PubMed ID: 17912441
    [Abstract] [Full Text] [Related]

  • 13. Human urine extract CDA-2 induces apoptosis of myelodysplastic syndrome-derived MUTZ-1 cells through the PI3K/Akt signaling pathway in a caspase-3-dependent manner.
    Huang J, Yang M, Liu H, Jin J.
    Acta Pharmacol Sin; 2008 Aug 15; 29(8):951-64. PubMed ID: 18664328
    [Abstract] [Full Text] [Related]

  • 14. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo.
    Hsu YL, Cho CY, Kuo PL, Huang YT, Lin CC.
    J Pharmacol Exp Ther; 2006 Aug 15; 318(2):484-94. PubMed ID: 16632641
    [Abstract] [Full Text] [Related]

  • 15. KRC-408, a novel c-Met inhibitor, suppresses cell proliferation and angiogenesis of gastric cancer.
    Hong SW, Jung KH, Park BH, Zheng HM, Lee HS, Choi MJ, Yun JI, Kang NS, Lee J, Hong SS.
    Cancer Lett; 2013 May 10; 332(1):74-82. PubMed ID: 23348694
    [Abstract] [Full Text] [Related]

  • 16. mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.
    Cejka D, Preusser M, Fuereder T, Sieghart W, Werzowa J, Strommer S, Wacheck V.
    Anticancer Res; 2008 May 10; 28(6A):3801-8. PubMed ID: 19189667
    [Abstract] [Full Text] [Related]

  • 17. IL-4 protects the B-cell lymphoma cell line CH31 from anti-IgM-induced growth arrest and apoptosis: contribution of the PI-3 kinase/AKT pathway.
    Carey GB, Semenova E, Qi X, Keegan AD.
    Cell Res; 2007 Nov 10; 17(11):942-55. PubMed ID: 17968425
    [Abstract] [Full Text] [Related]

  • 18. A small molecule compound inhibits AKT pathway in ovarian cancer cell lines.
    Tang HJ, Jin X, Wang S, Yang D, Cao Y, Chen J, Gossett DR, Lin J.
    Gynecol Oncol; 2006 Feb 10; 100(2):308-17. PubMed ID: 16209885
    [Abstract] [Full Text] [Related]

  • 19. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Shin SW, Seo CY, Han H, Han JY, Jeong JS, Kwak JY, Park JI.
    Clin Cancer Res; 2009 Sep 01; 15(17):5414-25. PubMed ID: 19690198
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects.
    Maffucci T, Piccolo E, Cumashi A, Iezzi M, Riley AM, Saiardi A, Godage HY, Rossi C, Broggini M, Iacobelli S, Potter BV, Innocenti P, Falasca M.
    Cancer Res; 2005 Sep 15; 65(18):8339-49. PubMed ID: 16166311
    [Abstract] [Full Text] [Related]

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