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88 related items for PubMed ID: 18363964

  • 1. Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.
    Hayakawa M, Matsushima M, Hagiwara H, Oshima T, Fujino T, Ando K, Kikugawa K, Tanaka H, Miyazawa K, Kitagawa M.
    Genes Cells; 2008 Apr; 13(4):329-42. PubMed ID: 18363964
    [Abstract] [Full Text] [Related]

  • 2. The FWD1/beta-TrCP-mediated degradation pathway establishes a 'turning off switch' of a Cdc42 guanine nucleotide exchange factor, FGD1.
    Hayakawa M, Kitagawa H, Miyazawa K, Kitagawa M, Kikugawa K.
    Genes Cells; 2005 Mar; 10(3):241-51. PubMed ID: 15743413
    [Abstract] [Full Text] [Related]

  • 3. Proline-rich domain plays a crucial role in extracellular stimuli-responsive translocation of a Cdc42 guanine nucleotide exchange factor, FGD1.
    Oshima T, Fujino T, Ando K, Hayakawa M.
    Biol Pharm Bull; 2010 Mar; 33(1):35-9. PubMed ID: 20045932
    [Abstract] [Full Text] [Related]

  • 4. Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue.
    Pasteris NG, Nagata K, Hall A, Gorski JL.
    Gene; 2000 Jan 25; 242(1-2):237-47. PubMed ID: 10721717
    [Abstract] [Full Text] [Related]

  • 5. Role of FGD1, a Cdc42 guanine nucleotide exchange factor, in epidermal growth factor-stimulated c-Jun NH2-terminal kinase activation and cell migration.
    Oshima T, Fujino T, Ando K, Hayakawa M.
    Biol Pharm Bull; 2011 Jan 25; 34(1):54-60. PubMed ID: 21212517
    [Abstract] [Full Text] [Related]

  • 6. Src kinase regulates the activation of a novel FGD-1-related Cdc42 guanine nucleotide exchange factor in the signaling pathway from the endothelin A receptor to JNK.
    Miyamoto Y, Yamauchi J, Itoh H.
    J Biol Chem; 2003 Aug 08; 278(32):29890-900. PubMed ID: 12771149
    [Abstract] [Full Text] [Related]

  • 7. Fgd1, the Cdc42 guanine nucleotide exchange factor responsible for faciogenital dysplasia, is localized to the subcortical actin cytoskeleton and Golgi membrane.
    Estrada L, Caron E, Gorski JL.
    Hum Mol Genet; 2001 Mar 01; 10(5):485-95. PubMed ID: 11181572
    [Abstract] [Full Text] [Related]

  • 8. The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor.
    Zheng Y, Fischer DJ, Santos MF, Tigyi G, Pasteris NG, Gorski JL, Xu Y.
    J Biol Chem; 1996 Dec 27; 271(52):33169-72. PubMed ID: 8969170
    [Abstract] [Full Text] [Related]

  • 9. Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues.
    Pasteris NG, Gorski JL.
    Genomics; 1999 Aug 15; 60(1):57-66. PubMed ID: 10458911
    [Abstract] [Full Text] [Related]

  • 10. M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP.
    Watanabe N, Arai H, Nishihara Y, Taniguchi M, Watanabe N, Hunter T, Osada H.
    Proc Natl Acad Sci U S A; 2004 Mar 30; 101(13):4419-24. PubMed ID: 15070733
    [Abstract] [Full Text] [Related]

  • 11. MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice.
    Zou W, Greenblatt MB, Shim JH, Kant S, Zhai B, Lotinun S, Brady N, Hu DZ, Gygi SP, Baron R, Davis RJ, Jones D, Glimcher LH.
    J Clin Invest; 2011 Nov 30; 121(11):4383-92. PubMed ID: 21965325
    [Abstract] [Full Text] [Related]

  • 12. The Aarskog-Scott syndrome protein Fgd1 regulates podosome formation and extracellular matrix remodeling in transforming growth factor β-stimulated aortic endothelial cells.
    Daubon T, Buccione R, Génot E.
    Mol Cell Biol; 2011 Nov 30; 31(22):4430-41. PubMed ID: 21911474
    [Abstract] [Full Text] [Related]

  • 13. Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.
    Hou P, Estrada L, Kinley AW, Parsons JT, Vojtek AB, Gorski JL.
    Hum Mol Genet; 2003 Aug 15; 12(16):1981-93. PubMed ID: 12913069
    [Abstract] [Full Text] [Related]

  • 14. Regulation of vesicle transport and cell motility by Golgi-localized Dbs.
    Fitzpatrick ER, Hu T, Ciccarelli BT, Whitehead IP.
    Small GTPases; 2014 Aug 15; 5(4):1-12. PubMed ID: 25483302
    [Abstract] [Full Text] [Related]

  • 15. Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in prostate and breast cancer.
    Ayala I, Giacchetti G, Caldieri G, Attanasio F, Mariggiò S, Tetè S, Polishchuk R, Castronovo V, Buccione R.
    Cancer Res; 2009 Feb 01; 69(3):747-52. PubMed ID: 19141649
    [Abstract] [Full Text] [Related]

  • 16. Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases.
    Olson MF, Pasteris NG, Gorski JL, Hall A.
    Curr Biol; 1996 Dec 01; 6(12):1628-33. PubMed ID: 8994827
    [Abstract] [Full Text] [Related]

  • 17. The Caenorhabditis elegans homolog of FGD1, the human Cdc42 GEF gene responsible for faciogenital dysplasia, is critical for excretory cell morphogenesis.
    Gao J, Estrada L, Cho S, Ellis RE, Gorski JL.
    Hum Mol Genet; 2001 Dec 15; 10(26):3049-62. PubMed ID: 11751687
    [Abstract] [Full Text] [Related]

  • 18. The Cdc42 guanine nucleotide exchange factor FGD1 regulates osteogenesis in human mesenchymal stem cells.
    Gao L, Gorski JL, Chen CS.
    Am J Pathol; 2011 Mar 15; 178(3):969-74. PubMed ID: 21356349
    [Abstract] [Full Text] [Related]

  • 19. CDC42 and FGD1 cause distinct signaling and transforming activities.
    Whitehead IP, Abe K, Gorski JL, Der CJ.
    Mol Cell Biol; 1998 Aug 15; 18(8):4689-97. PubMed ID: 9671479
    [Abstract] [Full Text] [Related]

  • 20. FGD1 as a central regulator of extracellular matrix remodelling--lessons from faciogenital dysplasia.
    Genot E, Daubon T, Sorrentino V, Buccione R.
    J Cell Sci; 2012 Jul 15; 125(Pt 14):3265-70. PubMed ID: 22854039
    [Abstract] [Full Text] [Related]

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