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Journal Abstract Search

185 related items for PubMed ID: 18372345

  • 21. Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor.
    Dong M, Li Z, Zang M, Pinon DI, Lybrand TP, Miller LJ.
    J Biol Chem; 2003 Nov 28; 278(48):48300-12. PubMed ID: 14500709
    [Abstract] [Full Text] [Related]

  • 22. Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.
    Dong M, Lam PC, Orry A, Sexton PM, Christopoulos A, Abagyan R, Miller LJ.
    J Biol Chem; 2016 Mar 04; 291(10):5172-84. PubMed ID: 26740626
    [Abstract] [Full Text] [Related]

  • 23. Informed development of drugs acting at family B G protein-coupled receptors.
    Miller LJ.
    Ann N Y Acad Sci; 2008 Nov 04; 1144():203-9. PubMed ID: 19076378
    [Abstract] [Full Text] [Related]

  • 24. Importance of each residue within secretin for receptor binding and biological activity.
    Dong M, Le A, Te JA, Pinon DI, Bordner AJ, Miller LJ.
    Biochemistry; 2011 Apr 12; 50(14):2983-93. PubMed ID: 21388146
    [Abstract] [Full Text] [Related]

  • 25. Agonist-induced internalization and recycling of the glucagon-like peptide-1 receptor in transfected fibroblasts and in insulinomas.
    Widmann C, Dolci W, Thorens B.
    Biochem J; 1995 Aug 15; 310 ( Pt 1)(Pt 1):203-14. PubMed ID: 7646446
    [Abstract] [Full Text] [Related]

  • 26. The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation.
    Estall JL, Koehler JA, Yusta B, Drucker DJ.
    J Biol Chem; 2005 Jun 10; 280(23):22124-34. PubMed ID: 15817468
    [Abstract] [Full Text] [Related]

  • 27. Interaction of amino acid residues at positions 8-15 of secretin with the N-terminal domain of the secretin receptor.
    Gourlet P, Vilardaga JP, De Neef P, Vandermeers A, Waelbroeck M, Bollen A, Robberecht P.
    Eur J Biochem; 1996 Jul 15; 239(2):349-55. PubMed ID: 8706739
    [Abstract] [Full Text] [Related]

  • 28. High potency antagonists of the pancreatic glucagon-like peptide-1 receptor.
    Montrose-Rafizadeh C, Yang H, Rodgers BD, Beday A, Pritchette LA, Eng J.
    J Biol Chem; 1997 Aug 22; 272(34):21201-6. PubMed ID: 9261127
    [Abstract] [Full Text] [Related]

  • 29. Differential impact of amino acid substitutions on critical residues of the human glucagon-like peptide-1 receptor involved in peptide activity and small-molecule allostery.
    Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM.
    J Pharmacol Exp Ther; 2015 Apr 22; 353(1):52-63. PubMed ID: 25630467
    [Abstract] [Full Text] [Related]

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  • 33. Speculations on the mechanism of hormone-receptor interactions of the secretin/glucagon family of polypeptide hormones derived from computational structural studies.
    Momany FA, Bowers CY.
    Ann N Y Acad Sci; 1996 Dec 26; 805():172-81; discussion 181-3. PubMed ID: 8993402
    [No Abstract] [Full Text] [Related]

  • 34. Lysine 173 residue within the first exoloop of rat secretin receptor is involved in carboxylate moiety recognition of Asp 3 in secretin.
    Vilardaga JP, di Paolo E, de Neef P, Waelbroeck M, Bollen A, Robberecht P.
    Biochem Biophys Res Commun; 1996 Jan 26; 218(3):842-6. PubMed ID: 8579602
    [Abstract] [Full Text] [Related]

  • 35. Localization of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor.
    Gelling RW, Wheeler MB, Xue J, Gyomorey S, Nian C, Pederson RA, McIntosh CH.
    Endocrinology; 1997 Jun 26; 138(6):2640-3. PubMed ID: 9165060
    [Abstract] [Full Text] [Related]

  • 36. Third intracellular loop of glucagon like-peptide-1 receptor is coupled with endogenous mono-ADP-ribosyltransferase - novel type of receptor regulation?
    Deželak M, Bavec A.
    Eur J Pharmacol; 2011 Sep 26; 666(1-3):35-42. PubMed ID: 21635883
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  • 38. Structural insights into RAMP modification of secretin family G protein-coupled receptors: implications for drug development.
    Archbold JK, Flanagan JU, Watkins HA, Gingell JJ, Hay DL.
    Trends Pharmacol Sci; 2011 Oct 26; 32(10):591-600. PubMed ID: 21722971
    [Abstract] [Full Text] [Related]

  • 39. The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists.
    Al-Sabah S, Donnelly D.
    FEBS Lett; 2003 Oct 23; 553(3):342-6. PubMed ID: 14572647
    [Abstract] [Full Text] [Related]

  • 40. Insights into the impact of phenolic residue incorporation at each position along secretin for receptor binding and biological activity.
    Dong M, Pinon DI, Miller LJ.
    Regul Pept; 2013 Jan 10; 180():5-11. PubMed ID: 23142313
    [Abstract] [Full Text] [Related]

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