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Journal Abstract Search

271 related items for PubMed ID: 18374191

  • 1. Quinone oxidoreductases and vitamin K metabolism.
    Gong X, Gutala R, Jaiswal AK.
    Vitam Horm; 2008; 78():85-101. PubMed ID: 18374191
    [Abstract] [Full Text] [Related]

  • 2. Interactions of the antioxidant enzymes NAD(P)H: Quinone oxidoreductase 1 (NQO1) and NRH: Quinone oxidoreductase 2 (NQO2) with pharmacological agents, endogenous biochemicals and environmental contaminants.
    Rashid MH, Babu D, Siraki AG.
    Chem Biol Interact; 2021 Aug 25; 345():109574. PubMed ID: 34228969
    [Abstract] [Full Text] [Related]

  • 3. Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain.
    Caspers M, Czogalla KJ, Liphardt K, Müller J, Westhofen P, Watzka M, Oldenburg J.
    Thromb Res; 2015 May 25; 135(5):977-83. PubMed ID: 25747820
    [Abstract] [Full Text] [Related]

  • 4. Assessment of the contribution of NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) to the reduction of vitamin K in wild-type and NQO1-deficient mice.
    Ingram BO, Turbyfill JL, Bledsoe PJ, Jaiswal AK, Stafford DW.
    Biochem J; 2013 Nov 15; 456(1):47-54. PubMed ID: 24015818
    [Abstract] [Full Text] [Related]

  • 5. NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones.
    Joseph P, Jaiswal AK.
    Br J Cancer; 1998 Mar 15; 77(5):709-19. PubMed ID: 9514048
    [Abstract] [Full Text] [Related]

  • 6. Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases.
    Jaiswal AK.
    Arch Biochem Biophys; 2000 Mar 01; 375(1):62-8. PubMed ID: 10683249
    [Abstract] [Full Text] [Related]

  • 7. The potent antioxidant activity of the vitamin K cycle in microsomal lipid peroxidation.
    Vervoort LM, Ronden JE, Thijssen HH.
    Biochem Pharmacol; 1997 Oct 15; 54(8):871-6. PubMed ID: 9354587
    [Abstract] [Full Text] [Related]

  • 8. Catalytic properties of NAD(P)H:quinone oxidoreductase-2 (NQO2), a dihydronicotinamide riboside dependent oxidoreductase.
    Wu K, Knox R, Sun XZ, Joseph P, Jaiswal AK, Zhang D, Deng PS, Chen S.
    Arch Biochem Biophys; 1997 Nov 15; 347(2):221-8. PubMed ID: 9367528
    [Abstract] [Full Text] [Related]

  • 9. Vitamin K1 2,3-epoxide and quinone reduction: mechanism and inhibition.
    Preusch PC, Smalley DM.
    Free Radic Res Commun; 1990 Nov 15; 8(4-6):401-15. PubMed ID: 2113031
    [Abstract] [Full Text] [Related]

  • 10. Dicoumarol: A Drug which Hits at Least Two Very Different Targets in Vitamin K Metabolism.
    Timson DJ.
    Curr Drug Targets; 2017 Nov 15; 18(5):500-510. PubMed ID: 26201483
    [Abstract] [Full Text] [Related]

  • 11. Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations.
    den Braver-Sewradj SP, den Braver MW, Toorneman RM, van Leeuwen S, Zhang Y, Dekker SJ, Vermeulen NPE, Commandeur JNM, Vos JC.
    Chem Res Toxicol; 2018 Feb 19; 31(2):116-126. PubMed ID: 29281794
    [Abstract] [Full Text] [Related]

  • 12. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J, Oleschuk CJ, Guziec F, Guziec L, Fiterman DJ, Monterrosa C, Begleiter A.
    Cancer Chemother Pharmacol; 2002 Feb 19; 49(2):101-10. PubMed ID: 11862423
    [Abstract] [Full Text] [Related]

  • 13. Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1.
    Chatron N, Hammed A, Benoît E, Lattard V.
    Nutrients; 2019 Jan 01; 11(1):. PubMed ID: 30609653
    [Abstract] [Full Text] [Related]

  • 14. NAD(P)H-dependent quinone oxidoreductase 1 (NQO1) and cytochrome P450 oxidoreductase (CYP450OR) differentially regulate menadione-mediated alterations in redox status, survival and metabolism in pancreatic β-cells.
    Gray JP, Karandrea S, Burgos DZ, Jaiswal AA, Heart EA.
    Toxicol Lett; 2016 Nov 16; 262():1-11. PubMed ID: 27558805
    [Abstract] [Full Text] [Related]

  • 15. Formation of 17-allylamino-demethoxygeldanamycin (17-AAG) hydroquinone by NAD(P)H:quinone oxidoreductase 1: role of 17-AAG hydroquinone in heat shock protein 90 inhibition.
    Guo W, Reigan P, Siegel D, Zirrolli J, Gustafson D, Ross D.
    Cancer Res; 2005 Nov 01; 65(21):10006-15. PubMed ID: 16267026
    [Abstract] [Full Text] [Related]

  • 16. Cooperation of NAD(P)H:quinone oxidoreductase 1 and UDP-glucuronosyltransferases reduces menadione cytotoxicity in HEK293 cells.
    Nishiyama T, Izawa T, Usami M, Ohnuma T, Ogura K, Hiratsuka A.
    Biochem Biophys Res Commun; 2010 Apr 09; 394(3):459-63. PubMed ID: 20035715
    [Abstract] [Full Text] [Related]

  • 17. Vitamin K-dependent carboxylation and vitamin K metabolism in liver. Effects of warfarin.
    Wallin R, Martin LF.
    J Clin Invest; 1985 Nov 09; 76(5):1879-84. PubMed ID: 3932474
    [Abstract] [Full Text] [Related]

  • 18. NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs.
    Celli CM, Tran N, Knox R, Jaiswal AK.
    Biochem Pharmacol; 2006 Jul 28; 72(3):366-76. PubMed ID: 16765324
    [Abstract] [Full Text] [Related]

  • 19. Comparison of the vitamins K1, K2 and K3 as cofactors for the hepatic vitamin K-dependent carboxylase.
    Buitenhuis HC, Soute BA, Vermeer C.
    Biochim Biophys Acta; 1990 May 16; 1034(2):170-5. PubMed ID: 2112953
    [Abstract] [Full Text] [Related]

  • 20. Evidence for NQO1 and NQO2 catalyzed reduction of ortho- and para-quinone methides.
    Kucera HR, Livingstone M, Moscoso CG, Gaikwad NW.
    Free Radic Res; 2013 Dec 16; 47(12):1016-26. PubMed ID: 24074361
    [Abstract] [Full Text] [Related]

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