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Journal Abstract Search

129 related items for PubMed ID: 18374566

  • 1. 2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis.
    Harikrishnan LS, Kamau MG, Herpin TF, Morton GC, Liu Y, Cooper CB, Salvati ME, Qiao JX, Wang TC, Adam LP, Taylor DS, Chen AY, Yin X, Seethala R, Peterson TL, Nirschl DS, Miller AV, Weigelt CA, Appiah KK, O'Connell JC, Michael Lawrence R.
    Bioorg Med Chem Lett; 2008 Apr 15; 18(8):2640-4. PubMed ID: 18374566
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  • 2. 2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.
    Kallashi F, Kim D, Kowalchick J, Park YJ, Hunt JA, Ali A, Smith CJ, Hammond ML, Pivnichny JV, Tong X, Xu SS, Anderson MS, Chen Y, Eveland SS, Guo Q, Hyland SA, Milot DP, Cumiskey AM, Latham M, Peterson LB, Rosa R, Sparrow CP, Wright SD, Sinclair PJ.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):558-61. PubMed ID: 21094047
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  • 3. 2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety.
    Smith CJ, Ali A, Chen L, Hammond ML, Anderson MS, Chen Y, Eveland SS, Guo Q, Hyland SA, Milot DP, Sparrow CP, Wright SD, Sinclair PJ.
    Bioorg Med Chem Lett; 2010 Jan 01; 20(1):346-9. PubMed ID: 19914065
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  • 4. 2-Arylbenzoxazoles as CETP inhibitors: substitution and modification of the alpha-alkoxyamide moiety.
    Hunt JA, Gonzalez S, Kallashi F, Hammond ML, Pivnichny JV, Tong X, Xu SS, Anderson MS, Chen Y, Eveland SS, Guo Q, Hyland SA, Milot DP, Sparrow CP, Wright SD, Sinclair PJ.
    Bioorg Med Chem Lett; 2010 Feb 01; 20(3):1019-22. PubMed ID: 20036121
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  • 5. 2-(4-carbonylphenyl)benzoxazole inhibitors of CETP: scaffold design and advancement in HDLc-raising efficacy.
    Sweis RF, Hunt JA, Kallashi F, Hammond ML, Chen Y, Eveland SS, Guo Q, Hyland SA, Milot DP, Cumiskey AM, Latham M, Rosa R, Peterson L, Sparrow CP, Wright SD, Anderson MS, Sinclair PJ.
    Bioorg Med Chem Lett; 2011 Mar 15; 21(6):1890-5. PubMed ID: 21147531
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  • 7. 2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: attenuation of hERG binding and improved HDLc-raising efficacy.
    Sweis RF, Hunt JA, Sinclair PJ, Chen Y, Eveland SS, Guo Q, Hyland SA, Milot DP, Cumiskey AM, Latham M, Rosa R, Peterson L, Sparrow CP, Anderson MS.
    Bioorg Med Chem Lett; 2011 May 01; 21(9):2597-600. PubMed ID: 21398121
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  • 9. Chromanol derivatives--a novel class of CETP inhibitors.
    Vakalopoulos A, Schmeck C, Thutewohl M, Li V, Bischoff H, Lustig K, Weber O, Paulsen H, Elias H.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):488-91. PubMed ID: 21084191
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  • 10. Synthesis and discovery of 2,3-dihydro-3,8-diphenylbenzo[1,4]oxazines as a novel class of potent cholesteryl ester transfer protein inhibitors.
    Wang A, Prouty CP, Pelton PD, Yong M, Demarest KT, Murray WV, Kuo GH.
    Bioorg Med Chem Lett; 2010 Feb 15; 20(4):1432-5. PubMed ID: 20089400
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  • 13. Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta.
    Gong B, Hong F, Kohm C, Bonham L, Klein P.
    Bioorg Med Chem Lett; 2004 Mar 22; 14(6):1455-9. PubMed ID: 15006381
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  • 15. Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration.
    Abu Khalaf R, Abu Sheikha G, Bustanji Y, Taha MO.
    Eur J Med Chem; 2010 Apr 22; 45(4):1598-617. PubMed ID: 20116902
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  • 16. Biophysical and biochemical approach to locating an inhibitor binding site on cholesteryl ester transfer protein.
    Cunningham D, Lin W, Hoth LR, Danley DE, Ruggeri RB, Geoghegan KF, Chrunyk BA, Boyd JG.
    Bioconjug Chem; 2008 Aug 22; 19(8):1604-13. PubMed ID: 18646836
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  • 18. Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors.
    Miller MM, Liu Y, Jiang J, Johnson JA, Kamau M, Nirschl DS, Wang Y, Harikrishnan L, Taylor DS, Chen AY, Yin X, Seethala R, Peterson TL, Zvyaga T, Zhang J, Huang CS, Wexler RR, Poss MA, Lawrence RM, Adam LP, Salvati ME.
    Bioorg Med Chem Lett; 2012 Oct 15; 22(20):6503-8. PubMed ID: 22995620
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  • 19. Cholesteryl ester transfer protein (CETP) inhibitors: is there life after torcetrapib?
    Neeli H, Rader DJ.
    Cardiol Clin; 2008 Nov 15; 26(4):537-46. PubMed ID: 18929230
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  • 20. Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors.
    Harikrishnan LS, Finlay HJ, Qiao JX, Kamau MG, Jiang J, Wang TC, Li J, Cooper CB, Poss MA, Adam LP, Taylor DS, Chen AY, Yin X, Sleph PG, Yang RZ, Sitkoff DF, Galella MA, Nirschl DS, Van Kirk K, Miller AV, Huang CS, Chang M, Chen XQ, Salvati ME, Wexler RR, Lawrence RM.
    J Med Chem; 2012 Jul 12; 55(13):6162-75. PubMed ID: 22650305
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