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148 related items for PubMed ID: 18375078

  • 1. The microbial PhIP metabolite 7-hydroxy-5-methyl-3-phenyl-6,7,8,9-tetrahydropyrido[3',2':4,5]imidazo[1,2-a]pyrimidin-5-ium chloride (PhIP-M1) induces DNA damage, apoptosis and cell cycle arrest towards Caco-2 cells.
    Vanhaecke L, Derycke L, Le Curieux F, Lust S, Marzin D, Verstraete W, Bracke M.
    Toxicol Lett; 2008 Apr 21; 178(1):61-9. PubMed ID: 18375078
    [Abstract] [Full Text] [Related]

  • 2. Intestinal bacteria metabolize the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine following consumption of a single cooked chicken meal in humans.
    Vanhaecke L, Knize MG, Noppe H, De Brabander H, Verstraete W, Van de Wiele T.
    Food Chem Toxicol; 2008 Jan 21; 46(1):140-8. PubMed ID: 17766021
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  • 5. Intestinal absorption and cell transforming potential of PhIP-M1, a bacterial metabolite of the heterocyclic aromatic amine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
    Nicken P, Willenberg I, Keutz Av, Elsner Lv, Hamscher G, Vanhaecke L, Schröder B, Breves G, Schebb NH, Steinberg P.
    Toxicol Lett; 2015 Apr 16; 234(2):92-8. PubMed ID: 25707896
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  • 6. The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Malfatti MA, Connors MS, Mauthe RJ, Felton JS.
    Cancer Res; 1996 Jun 01; 56(11):2550-5. PubMed ID: 8653696
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  • 8. Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells.
    Pezdirc M, Žegura B, Filipič M.
    Food Chem Toxicol; 2013 Sep 01; 59():386-94. PubMed ID: 23810796
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  • 9. DNA damage induced by a quinoxaline 1,4-di-N-oxide derivative (hypoxic selective agent) in Caco-2 cells evaluated by the comet assay.
    Azqueta A, Pachón G, Cascante M, Creppy EE, López de Cerain A.
    Mutagenesis; 2005 May 01; 20(3):165-71. PubMed ID: 15817574
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  • 10. Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine.
    Venugopal M, Agarwal R, Callaway A, Schut HA, Snyderwine EG.
    Biochem Biophys Res Commun; 1999 Dec 09; 266(1):203-7. PubMed ID: 10581190
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  • 11. The effect of UDP-glucuronosyltransferase 1A1 expression on the mutagenicity and metabolism of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in CHO cells.
    Malfatti MA, Wu RW, Felton JS.
    Mutat Res; 2005 Mar 01; 570(2):205-14. PubMed ID: 15708579
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  • 12. Age at exposure and Apc status influence the levels of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-DNA adducts in mouse intestine and liver.
    Steffensen IL, Schut HA, Alexander J.
    Mutat Res; 2005 Nov 10; 587(1-2):73-89. PubMed ID: 16202642
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  • 13. Primary cultures of prostate cells and their ability to activate carcinogens.
    Martin FL, Cole KJ, Muir GH, Kooiman GG, Williams JA, Sherwood RA, Grover PL, Phillips DH.
    Prostate Cancer Prostatic Dis; 2002 Nov 10; 5(2):96-104. PubMed ID: 12496996
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  • 14. Effects of (+)-catechin and (-)-epicatechin on heterocyclic amines-induced oxidative DNA damage.
    Haza AI, Morales P.
    J Appl Toxicol; 2011 Jan 10; 31(1):53-62. PubMed ID: 20583320
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  • 15. Development of an online-SPE-LC-MS method for the investigation of the intestinal absorption of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PHIP) and its bacterial metabolite PHIP-M1 in a Caco-2 Transwell system.
    Willenberg I, von Elsner L, Steinberg P, Schebb NH.
    Food Chem; 2015 Jan 01; 166():537-543. PubMed ID: 25053091
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  • 16. Genotoxicity assessment of deoxynivalenol in the Caco-2 cell line model using the Comet assay.
    Bony S, Carcelen M, Olivier L, Devaux A.
    Toxicol Lett; 2006 Sep 30; 166(1):67-76. PubMed ID: 16828243
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  • 17. Anti-proliferation, cell cycle arrest and apoptosis induced by a natural xanthone from Gentianopsis paludosa Ma, in human promyelocytic leukemia cell line HL-60 cells.
    Ding L, Liu B, Qi LL, Zhou QY, Hou Q, Li J, Zhang Q.
    Toxicol In Vitro; 2009 Apr 30; 23(3):408-17. PubMed ID: 19344684
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  • 18. Patulin causes DNA damage leading to cell cycle arrest and apoptosis through modulation of Bax, p(53) and p(21/WAF1) proteins in skin of mice.
    Saxena N, Ansari KM, Kumar R, Dhawan A, Dwivedi PD, Das M.
    Toxicol Appl Pharmacol; 2009 Jan 15; 234(2):192-201. PubMed ID: 19000704
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  • 19. Malignant transformation of human colon epithelial cells by benzo[c]phenanthrene dihydrodiolepoxides as well as 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Herbst U, Fuchs JI, Teubner W, Steinberg P.
    Toxicol Appl Pharmacol; 2006 Apr 15; 212(2):136-45. PubMed ID: 16137733
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  • 20. Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
    Dumont J, Jossé R, Lambert C, Anthérieu S, Le Hegarat L, Aninat C, Robin MA, Guguen-Guillouzo C, Guillouzo A.
    Toxicol Appl Pharmacol; 2010 Jun 01; 245(2):256-63. PubMed ID: 20307560
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