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436 related items for PubMed ID: 18379441

  • 1. Apolipoprotein E, amyloid-beta, and blood-brain barrier permeability in Alzheimer disease.
    Donahue JE, Johanson CE.
    J Neuropathol Exp Neurol; 2008 Apr; 67(4):261-70. PubMed ID: 18379441
    [Abstract] [Full Text] [Related]

  • 2. Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology.
    Baum L, Chen L, Ng HK, Pang CP.
    Microsc Res Tech; 2000 Aug 15; 50(4):278-81. PubMed ID: 10936880
    [Abstract] [Full Text] [Related]

  • 3. Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes.
    Utter S, Tamboli IY, Walter J, Upadhaya AR, Birkenmeier G, Pietrzik CU, Ghebremedhin E, Thal DR.
    J Neuropathol Exp Neurol; 2008 Sep 15; 67(9):842-56. PubMed ID: 18716559
    [Abstract] [Full Text] [Related]

  • 4. Apolipoprotein E co-localizes with newly formed amyloid beta-protein (Abeta) deposits lacking immunoreactivity against N-terminal epitopes of Abeta in a genotype-dependent manner.
    Thal DR, Capetillo-Zarate E, Schultz C, Rüb U, Saido TC, Yamaguchi H, Haass C, Griffin WS, Del Tredici K, Braak H, Ghebremedhin E.
    Acta Neuropathol; 2005 Nov 15; 110(5):459-71. PubMed ID: 16195918
    [Abstract] [Full Text] [Related]

  • 5. A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade.
    Dolev I, Michaelson DM.
    Proc Natl Acad Sci U S A; 2004 Sep 21; 101(38):13909-14. PubMed ID: 15365176
    [Abstract] [Full Text] [Related]

  • 6. Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease.
    Dodart JC, Marr RA, Koistinaho M, Gregersen BM, Malkani S, Verma IM, Paul SM.
    Proc Natl Acad Sci U S A; 2005 Jan 25; 102(4):1211-6. PubMed ID: 15657137
    [Abstract] [Full Text] [Related]

  • 7. Greasing the wheels of Abeta clearance in Alzheimer's disease: the role of lipids and apolipoprotein E.
    Fan J, Donkin J, Wellington C.
    Biofactors; 2009 Jan 25; 35(3):239-48. PubMed ID: 19472365
    [Abstract] [Full Text] [Related]

  • 8. Blood-brain barrier permeability correlates with medial temporal lobe atrophy but not with amyloid-beta protein transport across the blood-brain barrier in Alzheimer's disease.
    Matsumoto Y, Yanase D, Noguchi-Shinohara M, Ono K, Yoshita M, Yamada M.
    Dement Geriatr Cogn Disord; 2007 Jan 25; 23(4):241-5. PubMed ID: 17310121
    [Abstract] [Full Text] [Related]

  • 9. Apolipoprotein E protects cultured pericytes and astrocytes from D-Abeta(1-40)-mediated cell death.
    Bruinsma IB, Wilhelmus MM, Kox M, Veerhuis R, de Waal RM, Verbeek MM.
    Brain Res; 2010 Feb 22; 1315():169-80. PubMed ID: 20034483
    [Abstract] [Full Text] [Related]

  • 10. Cerebral beta-amyloid deposition is augmented by the -491AA promoter polymorphism in non-demented elderly individuals bearing the apolipoprotein E epsilon4 allele.
    Pahnke J, Walker LC, Schroeder E, Vogelgesang S, Stausske D, Walther R, Warzok RW.
    Acta Neuropathol; 2003 Jan 22; 105(1):25-9. PubMed ID: 12471457
    [Abstract] [Full Text] [Related]

  • 11. Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.
    Fagan AM, Watson M, Parsadanian M, Bales KR, Paul SM, Holtzman DM.
    Neurobiol Dis; 2002 Apr 22; 9(3):305-18. PubMed ID: 11950276
    [Abstract] [Full Text] [Related]

  • 12. Cerebral clearance of human amyloid-beta peptide (1-40) across the blood-brain barrier is reduced by self-aggregation and formation of low-density lipoprotein receptor-related protein-1 ligand complexes.
    Ito S, Ohtsuki S, Kamiie J, Nezu Y, Terasaki T.
    J Neurochem; 2007 Dec 22; 103(6):2482-90. PubMed ID: 17908238
    [Abstract] [Full Text] [Related]

  • 13. Abeta peptides can enter the brain through a defective blood-brain barrier and bind selectively to neurons.
    Clifford PM, Zarrabi S, Siu G, Kinsler KJ, Kosciuk MC, Venkataraman V, D'Andrea MR, Dinsmore S, Nagele RG.
    Brain Res; 2007 Apr 20; 1142():223-36. PubMed ID: 17306234
    [Abstract] [Full Text] [Related]

  • 14. Independent effects of APOE on cholesterol metabolism and brain Abeta levels in an Alzheimer disease mouse model.
    Mann KM, Thorngate FE, Katoh-Fukui Y, Hamanaka H, Williams DL, Fujita S, Lamb BT.
    Hum Mol Genet; 2004 Sep 01; 13(17):1959-68. PubMed ID: 15229191
    [Abstract] [Full Text] [Related]

  • 15. Dietary fats, cerebrovasculature integrity and Alzheimer's disease risk.
    Takechi R, Galloway S, Pallebage-Gamarallage MM, Lam V, Mamo JC.
    Prog Lipid Res; 2010 Apr 01; 49(2):159-70. PubMed ID: 19896503
    [Abstract] [Full Text] [Related]

  • 16. Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests.
    Bates KA, Verdile G, Li QX, Ames D, Hudson P, Masters CL, Martins RN.
    Mol Psychiatry; 2009 May 01; 14(5):469-86. PubMed ID: 18794889
    [Abstract] [Full Text] [Related]

  • 17. Cerebrovascular smooth muscle cells internalize Alzheimer amyloid beta protein via a lipoprotein pathway: implications for cerebral amyloid angiopathy.
    Urmoneit B, Prikulis I, Wihl G, D'Urso D, Frank R, Heeren J, Beisiegel U, Prior R.
    Lab Invest; 1997 Aug 01; 77(2):157-66. PubMed ID: 9274858
    [Abstract] [Full Text] [Related]

  • 18. Co-expression of beta-amyloid precursor protein (betaAPP) and apolipoprotein E in cell culture: analysis of betaAPP processing.
    Biere AL, Ostaszewski B, Zhao H, Gillespie S, Younkin SG, Selkoe DJ.
    Neurobiol Dis; 1995 Jun 01; 2(3):177-87. PubMed ID: 9174001
    [Abstract] [Full Text] [Related]

  • 19. Occurrence and co-localization of amyloid beta-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice.
    Thal DR, Larionov S, Abramowski D, Wiederhold KH, Van Dooren T, Yamaguchi H, Haass C, Van Leuven F, Staufenbiel M, Capetillo-Zarate E.
    Neurobiol Aging; 2007 Aug 01; 28(8):1221-30. PubMed ID: 16815595
    [Abstract] [Full Text] [Related]

  • 20. A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier.
    Bachmeier C, Paris D, Beaulieu-Abdelahad D, Mouzon B, Mullan M, Crawford F.
    Neurodegener Dis; 2013 Aug 01; 11(1):13-21. PubMed ID: 22572854
    [Abstract] [Full Text] [Related]

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