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168 related items for PubMed ID: 18398379

  • 1. Ranolazine inhibits an oxidative stress-induced increase in myocyte sodium and calcium loading during simulated-demand ischemia.
    Zhang XQ, Yamada S, Barry WH.
    J Cardiovasc Pharmacol; 2008 May; 51(5):443-9. PubMed ID: 18398379
    [Abstract] [Full Text] [Related]

  • 2. Direct toxic effects of aqueous extract of cigarette smoke on cardiac myocytes at clinically relevant concentrations.
    Yamada S, Zhang XQ, Kadono T, Matsuoka N, Rollins D, Badger T, Rodesch CK, Barry WH.
    Toxicol Appl Pharmacol; 2009 Apr 01; 236(1):71-7. PubMed ID: 19371621
    [Abstract] [Full Text] [Related]

  • 3. Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation.
    Sossalla S, Wagner S, Rasenack EC, Ruff H, Weber SL, Schöndube FA, Tirilomis T, Tenderich G, Hasenfuss G, Belardinelli L, Maier LS.
    J Mol Cell Cardiol; 2008 Jul 01; 45(1):32-43. PubMed ID: 18439620
    [Abstract] [Full Text] [Related]

  • 4. The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-L-carnitine to increase late INa and cause ventricular diastolic dysfunction.
    Wu Y, Song Y, Belardinelli L, Shryock JC.
    J Pharmacol Exp Ther; 2009 Aug 01; 330(2):550-7. PubMed ID: 19403851
    [Abstract] [Full Text] [Related]

  • 5. Nonanticoagulant heparin reduces myocyte Na+ and Ca2+ loading during simulated ischemia and decreases reperfusion injury.
    Barry WH, Zhang XQ, Halkos ME, Vinten-Johansen J, Saegusa N, Spitzer KW, Matsuoka N, Sheets M, Rao NV, Kennedy TP.
    Am J Physiol Heart Circ Physiol; 2010 Jan 01; 298(1):H102-11. PubMed ID: 19855066
    [Abstract] [Full Text] [Related]

  • 6. Reducing the late sodium current improves cardiac function during sodium pump inhibition by ouabain.
    Hoyer K, Song Y, Wang D, Phan D, Balschi J, Ingwall JS, Belardinelli L, Shryock JC.
    J Pharmacol Exp Ther; 2011 May 01; 337(2):513-23. PubMed ID: 21325441
    [Abstract] [Full Text] [Related]

  • 7. Ranolazine, an inhibitor of the late sodium channel current, reduces postischemic myocardial dysfunction in the rabbit.
    Hale SL, Kloner RA.
    J Cardiovasc Pharmacol Ther; 2006 Dec 01; 11(4):249-55. PubMed ID: 17220471
    [Abstract] [Full Text] [Related]

  • 8. Effects of angiotensin II on intracellular calcium and contracture in metabolically inhibited cardiomyocytes.
    Boston DR, Koyama T, Rodriguez-Larrain J, Zou A, Su Z, Barry WH.
    J Pharmacol Exp Ther; 1998 May 01; 285(2):716-23. PubMed ID: 9580618
    [Abstract] [Full Text] [Related]

  • 9. Differential effects of the sodium calcium exchange inhibitor, KB-R7943, on ischemia and reperfusion injury in isolated guinea pig ventricular myocytes.
    MacDonald AC, Howlett SE.
    Eur J Pharmacol; 2008 Feb 02; 580(1-2):214-23. PubMed ID: 18036586
    [Abstract] [Full Text] [Related]

  • 10. Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition.
    Li F, Sugishita K, Su Z, Ueda I, Barry WH.
    J Mol Cell Cardiol; 2001 Dec 02; 33(12):2145-55. PubMed ID: 11735261
    [Abstract] [Full Text] [Related]

  • 11. Characterization of SN-6, a novel Na+/Ca2+ exchange inhibitor in guinea pig cardiac ventricular myocytes.
    Niu CF, Watanabe Y, Ono K, Iwamoto T, Yamashita K, Satoh H, Urushida T, Hayashi H, Kimura J.
    Eur J Pharmacol; 2007 Nov 14; 573(1-3):161-9. PubMed ID: 17644086
    [Abstract] [Full Text] [Related]

  • 12. Role of reverse mode Na+/Ca2+ exchanger in the cardioprotection of metabolic inhibition preconditioning in rat ventricular myocytes.
    Li SZ, Wu F, Wang B, Wei GZ, Jin ZX, Zang YM, Zhou JJ, Wong TM.
    Eur J Pharmacol; 2007 Apr 30; 561(1-3):14-22. PubMed ID: 17306252
    [Abstract] [Full Text] [Related]

  • 13. Ranolazine antagonizes the effects of increased late sodium current on intracellular calcium cycling in rat isolated intact heart.
    Wasserstrom JA, Sharma R, O'Toole MJ, Zheng J, Kelly JE, Shryock J, Belardinelli L, Aistrup GL.
    J Pharmacol Exp Ther; 2009 Nov 30; 331(2):382-91. PubMed ID: 19675298
    [Abstract] [Full Text] [Related]

  • 14. Ranolazine as a cardioplegia additive improves recovery of diastolic function in isolated rat hearts.
    Hwang H, Arcidi JM, Hale SL, Simkhovich BZ, Belardinelli L, Dhalla AK, Shryock JC, Kloner RA.
    Circulation; 2009 Sep 15; 120(11 Suppl):S16-21. PubMed ID: 19752362
    [Abstract] [Full Text] [Related]

  • 15. Late sodium current inhibition alone with ranolazine is sufficient to reduce ischemia- and cardiac glycoside-induced calcium overload and contractile dysfunction mediated by reverse-mode sodium/calcium exchange.
    Soliman D, Wang L, Hamming KS, Yang W, Fatehi M, Carter CC, Clanachan AS, Light PE.
    J Pharmacol Exp Ther; 2012 Nov 15; 343(2):325-32. PubMed ID: 22879384
    [Abstract] [Full Text] [Related]

  • 16. Resveratrol attenuates the Na(+)-dependent intracellular Ca(2+) overload by inhibiting H(2)O(2)-induced increase in late sodium current in ventricular myocytes.
    Qian C, Ma J, Zhang P, Luo A, Wang C, Ren Z, Kong L, Zhang S, Wang X, Wu Y.
    PLoS One; 2012 Nov 15; 7(12):e51358. PubMed ID: 23272101
    [Abstract] [Full Text] [Related]

  • 17. Ranolazine decreases diastolic calcium accumulation caused by ATX-II or ischemia in rat hearts.
    Fraser H, Belardinelli L, Wang L, Light PE, McVeigh JJ, Clanachan AS.
    J Mol Cell Cardiol; 2006 Dec 15; 41(6):1031-8. PubMed ID: 17027025
    [Abstract] [Full Text] [Related]

  • 18. Ranolazine improves abnormal repolarization and contraction in left ventricular myocytes of dogs with heart failure by inhibiting late sodium current.
    Undrovinas AI, Belardinelli L, Undrovinas NA, Sabbah HN.
    J Cardiovasc Electrophysiol; 2006 May 15; 17 Suppl 1(Suppl 1):S169-S177. PubMed ID: 16686675
    [Abstract] [Full Text] [Related]

  • 19. [Involvement of veratridine-induced increase of reverse Na(+)/Ca(2+) exchange current in intracellular Ca(2+) overload and extension of action potential duration in rabbit ventricular myocytes].
    Kong LH, Ma JH, Zhang PH, Luo AT, Zhang S, Ren ZQ, Feng J, Chen JL.
    Sheng Li Xue Bao; 2012 Aug 25; 64(4):433-43. PubMed ID: 22907304
    [Abstract] [Full Text] [Related]

  • 20. Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity.
    Lovelock JD, Monasky MM, Jeong EM, Lardin HA, Liu H, Patel BG, Taglieri DM, Gu L, Kumar P, Pokhrel N, Zeng D, Belardinelli L, Sorescu D, Solaro RJ, Dudley SC.
    Circ Res; 2012 Mar 16; 110(6):841-50. PubMed ID: 22343711
    [Abstract] [Full Text] [Related]

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