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PUBMED FOR HANDHELDS

Journal Abstract Search


271 related items for PubMed ID: 18407496

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  • 2. Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines.
    Gillespie RJ, Cliffe IA, Dawson CE, Dourish CT, Gaur S, Jordan AM, Knight AR, Lerpiniere J, Misra A, Pratt RM, Roffey J, Stratton GC, Upton R, Weiss SM, Williamson DS.
    Bioorg Med Chem Lett; 2008 May 01; 18(9):2924-9. PubMed ID: 18411049
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  • 3. Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives.
    Gillespie RJ, Adams DR, Bebbington D, Benwell K, Cliffe IA, Dawson CE, Dourish CT, Fletcher A, Gaur S, Giles PR, Jordan AM, Knight AR, Knutsen LJ, Lawrence A, Lerpiniere J, Misra A, Porter RH, Pratt RM, Shepherd R, Upton R, Ward SE, Weiss SM, Williamson DS.
    Bioorg Med Chem Lett; 2008 May 01; 18(9):2916-9. PubMed ID: 18406614
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  • 4. Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
    Carotti A, Cadavid MI, Centeno NB, Esteve C, Loza MI, Martinez A, Nieto R, Raviña E, Sanz F, Segarra V, Sotelo E, Stefanachi A, Vidal B.
    J Med Chem; 2006 Jan 12; 49(1):282-99. PubMed ID: 16392813
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  • 7. Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.
    Cosimelli B, Greco G, Ehlardo M, Novellino E, Da Settimo F, Taliani S, La Motta C, Bellandi M, Tuccinardi T, Martinelli A, Ciampi O, Trincavelli ML, Martini C.
    J Med Chem; 2008 Mar 27; 51(6):1764-70. PubMed ID: 18269230
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  • 10. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
    Balo MC, Brea J, Caamaño O, Fernández F, García-Mera X, López C, Loza MI, Nieto MI, Rodríguez-Borges JE.
    Bioorg Med Chem; 2009 Sep 15; 17(18):6755-60. PubMed ID: 19682912
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  • 11. Synthesis, biological and modeling studies of 1,3-di-n-propyl-2,4-dioxo-6-methyl-8-(substituted) 1,2,3,4-tetrahydro [1,2,4]-triazolo [3,4-f]-purines as adenosine receptor antagonists.
    Pastorin G, Bolcato C, Cacciari B, Kachler S, Klotz KN, Montopoli C, Moro S, Spalluto G.
    Farmaco; 2005 Aug 15; 60(8):643-51. PubMed ID: 15961085
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  • 12. Discovery and optimization of potent and selective functional antagonists of the human adenosine A2B receptor.
    Bedford ST, Benwell KR, Brooks T, Chen I, Comer M, Dugdale S, Haymes T, Jordan AM, Kennett GA, Knight AR, Klenke B, LeStrat L, Merrett A, Misra A, Lightowler S, Padfield A, Poullennec K, Reece M, Simmonite H, Wong M, Yule IA.
    Bioorg Med Chem Lett; 2009 Oct 15; 19(20):5945-9. PubMed ID: 19733067
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  • 18. Design, synthesis, and biological evaluation of a second generation of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as potent and selective A2A adenosine receptor antagonists.
    Baraldi PG, Cacciari B, Spalluto G, Bergonzoni M, Dionisotti S, Ongini E, Varani K, Borea PA.
    J Med Chem; 1998 Jun 04; 41(12):2126-33. PubMed ID: 9622554
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  • 20. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
    Baraldi PG, Fruttarolo F, Tabrizi MA, Preti D, Romagnoli R, El-Kashef H, Moorman A, Varani K, Gessi S, Merighi S, Borea PA.
    J Med Chem; 2003 Mar 27; 46(7):1229-41. PubMed ID: 12646033
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