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224 related items for PubMed ID: 18411234

  • 1. Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.
    Lipinski RJ, Hutson PR, Hannam PW, Nydza RJ, Washington IM, Moore RW, Girdaukas GG, Peterson RE, Bushman W.
    Toxicol Sci; 2008 Jul; 104(1):189-97. PubMed ID: 18411234
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  • 2. Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications.
    Lipinski RJ, Song C, Sulik KK, Everson JL, Gipp JJ, Yan D, Bushman W, Rowland IJ.
    Birth Defects Res A Clin Mol Teratol; 2010 Apr; 88(4):232-40. PubMed ID: 20213699
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  • 3. Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.
    Lipinski RJ, Holloway HT, O'Leary-Moore SK, Ament JJ, Pecevich SJ, Cofer GP, Budin F, Everson JL, Johnson GA, Sulik KK.
    PLoS One; 2014 Apr; 9(7):e102603. PubMed ID: 25047453
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  • 4. Identification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signaling.
    Lipinski RJ, Dengler E, Kiehn M, Peterson RE, Bushman W.
    Toxicol Sci; 2007 Dec; 100(2):456-63. PubMed ID: 17728282
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  • 6. Definition of critical periods for Hedgehog pathway antagonist-induced holoprosencephaly, cleft lip, and cleft palate.
    Heyne GW, Melberg CG, Doroodchi P, Parins KF, Kietzman HW, Everson JL, Ansen-Wilson LJ, Lipinski RJ.
    PLoS One; 2015 Dec; 10(3):e0120517. PubMed ID: 25793997
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  • 7. Teratogenic effects of cyclopamine and jervine in rats, mice and hamsters.
    Keeler RF.
    Proc Soc Exp Biol Med; 1975 May; 149(1):302-6. PubMed ID: 1144444
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  • 12. Oral, osmotic minipump, and intramuscular administration to sheep of the Veratrum alkaloid cyclopamine.
    Keeler RF, Baker DC.
    Proc Soc Exp Biol Med; 1989 Nov; 192(2):153-6. PubMed ID: 2813445
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  • 15. Hedgehog antagonist cyclopamine isomerizes to less potent forms when acidified.
    Wilson SR, Strand MF, Krapp A, Rise F, Petersen D, Krauss S.
    J Pharm Biomed Anal; 2010 Sep 05; 52(5):707-13. PubMed ID: 20236786
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  • 17. Expression of Veratrum alkaloid teratogenicity in the mouse.
    Omnell ML, Sim FR, Keeler RF, Harne LC, Brown KS.
    Teratology; 1990 Aug 05; 42(2):105-19. PubMed ID: 2218940
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  • 18. Development of an enzyme-linked immunosorbent assay for the veratrum plant teratogens: cyclopamine and jervine.
    Lee ST, Panter KE, Gaffield W, Stegelmeier BL.
    J Agric Food Chem; 2003 Jan 29; 51(3):582-6. PubMed ID: 12537426
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