These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

399 related items for PubMed ID: 18411402

  • 1. Bioactivation of flutamide metabolites by human liver microsomes.
    Kang P, Dalvie D, Smith E, Zhou S, Deese A, Nieman JA.
    Drug Metab Dispos; 2008 Jul; 36(7):1425-37. PubMed ID: 18411402
    [Abstract] [Full Text] [Related]

  • 2. Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients.
    Goda R, Nagai D, Akiyama Y, Nishikawa K, Ikemoto I, Aizawa Y, Nagata K, Yamazoe Y.
    Drug Metab Dispos; 2006 May; 34(5):828-35. PubMed ID: 16507648
    [Abstract] [Full Text] [Related]

  • 3. Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.
    Kang P, Dalvie D, Smith E, Zhou S, Deese A.
    Drug Metab Dispos; 2007 Jul; 35(7):1081-8. PubMed ID: 17403914
    [Abstract] [Full Text] [Related]

  • 4. Bioactivation of the tricyclic antidepressant amitriptyline and its metabolite nortriptyline to arene oxide intermediates in human liver microsomes and recombinant P450s.
    Wen B, Ma L, Zhu M.
    Chem Biol Interact; 2008 May 09; 173(1):59-67. PubMed ID: 18359012
    [Abstract] [Full Text] [Related]

  • 5. Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.
    Tevell A, Lennernäs H, Jönsson M, Norlin M, Lennernäs B, Bondesson U, Hedeland M.
    Drug Metab Dispos; 2006 Jun 09; 34(6):984-92. PubMed ID: 16540588
    [Abstract] [Full Text] [Related]

  • 6. Investigation of bioactivation of ticlopidine using linear ion trap/orbitrap mass spectrometry and an improved mass defect filtering technique.
    Ruan Q, Zhu M.
    Chem Res Toxicol; 2010 May 17; 23(5):909-17. PubMed ID: 20297803
    [Abstract] [Full Text] [Related]

  • 7. Comparison of in vitro bioactivation of flutamide and its cyano analogue: evidence for reductive activation by human NADPH:cytochrome P450 reductase.
    Wen B, Coe KJ, Rademacher P, Fitch WL, Monshouwer M, Nelson SD.
    Chem Res Toxicol; 2008 Dec 17; 21(12):2393-406. PubMed ID: 19548358
    [Abstract] [Full Text] [Related]

  • 8. Trimethoprim: novel reactive intermediates and bioactivation pathways by cytochrome p450s.
    Damsten MC, de Vlieger JS, Niessen WM, Irth H, Vermeulen NP, Commandeur JN.
    Chem Res Toxicol; 2008 Nov 17; 21(11):2181-7. PubMed ID: 18816075
    [Abstract] [Full Text] [Related]

  • 9. Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites.
    Tang W, Stearns RA, Bandiera SM, Zhang Y, Raab C, Braun MP, Dean DC, Pang J, Leung KH, Doss GA, Strauss JR, Kwei GY, Rushmore TH, Chiu SH, Baillie TA.
    Drug Metab Dispos; 1999 Mar 17; 27(3):365-72. PubMed ID: 10064567
    [Abstract] [Full Text] [Related]

  • 10.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 11. In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism.
    Yu J, Brown DG, Burdette D.
    Drug Metab Dispos; 2010 Oct 17; 38(10):1767-78. PubMed ID: 20595377
    [Abstract] [Full Text] [Related]

  • 12. Metabolic activation of the phenothiazine antipsychotics chlorpromazine and thioridazine to electrophilic iminoquinone species in human liver microsomes and recombinant P450s.
    Wen B, Zhou M.
    Chem Biol Interact; 2009 Oct 07; 181(2):220-6. PubMed ID: 19482014
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14. Identification of primary and sequential bioactivation pathways of carbamazepine in human liver microsomes using liquid chromatography/tandem mass spectrometry.
    Bu HZ, Zhao P, Dalvie DK, Pool WF.
    Rapid Commun Mass Spectrom; 2007 Oct 07; 21(20):3317-22. PubMed ID: 17879390
    [Abstract] [Full Text] [Related]

  • 15. NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions: identification of an electrophilic quinone metabolite of paroxetine.
    Zhao SX, Dalvie DK, Kelly JM, Soglia JR, Frederick KS, Smith EB, Obach RS, Kalgutkar AS.
    Chem Res Toxicol; 2007 Nov 07; 20(11):1649-57. PubMed ID: 17907785
    [Abstract] [Full Text] [Related]

  • 16. Bioactivation of coumarin in rat olfactory mucosal microsomes: Detection of protein covalent binding and identification of reactive intermediates through analysis of glutathione adducts.
    Zhuo X, Zhao W, Zheng J, Humphreys WG, Shu YZ, Zhu M.
    Chem Biol Interact; 2009 Oct 07; 181(2):227-35. PubMed ID: 19576871
    [Abstract] [Full Text] [Related]

  • 17. A semiquantitative method for the determination of reactive metabolite conjugate levels in vitro utilizing liquid chromatography-tandem mass spectrometry and novel quaternary ammonium glutathione analogues.
    Soglia JR, Contillo LG, Kalgutkar AS, Zhao S, Hop CE, Boyd JG, Cole MJ.
    Chem Res Toxicol; 2006 Mar 07; 19(3):480-90. PubMed ID: 16544956
    [Abstract] [Full Text] [Related]

  • 18. Metabolism and bioactivation of 3-methylindole by human liver microsomes.
    Yan Z, Easterwood LM, Maher N, Torres R, Huebert N, Yost GS.
    Chem Res Toxicol; 2007 Jan 07; 20(1):140-8. PubMed ID: 17226936
    [Abstract] [Full Text] [Related]

  • 19. Bioactivation of 4-ipomeanol by CYP4B1: adduct characterization and evidence for an enedial intermediate.
    Baer BR, Rettie AE, Henne KR.
    Chem Res Toxicol; 2005 May 07; 18(5):855-64. PubMed ID: 15892579
    [Abstract] [Full Text] [Related]

  • 20. Metabolism of the antiandrogenic drug (Flutamide) by human CYP1A2.
    Shet MS, McPhaul M, Fisher CW, Stallings NR, Estabrook RW.
    Drug Metab Dispos; 1997 Nov 07; 25(11):1298-303. PubMed ID: 9351907
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 20.