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Journal Abstract Search

195 related items for PubMed ID: 18423766

  • 1. Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes.
    Meng M, Liu Y, Wang YB, Wang JC, Zhang H, Wang XQ, Zhang X, Lu WL, Zhang Q.
    J Control Release; 2008 Jun 04; 128(2):113-9. PubMed ID: 18423766
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  • 3. [The pharmacokinetics and pharmacodynamics of recombinant hirudin-2 nasal spray].
    Zhang YJ, Zhang Q, Hou JL, Wang XL, Chen MX.
    Yao Xue Xue Bao; 2006 Mar 04; 41(3):268-71. PubMed ID: 16759001
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  • 7. Permeation-enhancing effects of chitosan formulations on recombinant hirudin-2 by nasal delivery in vitro and in vivo.
    Zhang YJ, Ma CH, Lu WL, Zhang X, Wang XL, Sun JN, Zhang Q.
    Acta Pharmacol Sin; 2005 Nov 04; 26(11):1402-8. PubMed ID: 16225765
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  • 9. [Studies on preparation of recombinant hirudin-2 liposome and its pharmacokinetics by nasal delivery in rats].
    Zhang YJ, Wang XL, Wu JM, Cheng MX.
    Zhongguo Zhong Yao Za Zhi; 2007 May 04; 32(9):801-4. PubMed ID: 17639978
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  • 10. Gastrointestinal absorption of recombinant hirudin-2 in rats.
    Yan X, Wang X, Zhang X, Zhang Q.
    J Pharmacol Exp Ther; 2004 Feb 04; 308(2):774-9. PubMed ID: 14610232
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  • 12. [Cationic liposomes loaded with doxorubicin targeting to the tumor neovasculature in vitro].
    Zhao W, Ma HL, Qi XR.
    Yao Xue Xue Bao; 2007 Sep 04; 42(9):982-8. PubMed ID: 18050743
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  • 14. Nasal recombinant hirudin-2 delivery: absorption and its mechanism in vivo and in vitro studies.
    Zhang Y, Zhang Q, Sun Y, Sun J, Wang X, Chen M.
    Biol Pharm Bull; 2005 Dec 04; 28(12):2263-7. PubMed ID: 16327162
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  • 15. Alteration of pharmacokinetics and pharmacodynamics of recombinant hirudin (rHV2-Lys 47) after repeated intravenous administration in dogs.
    Iyer L, Shavit J, Koza M, Calabria R, Moran S, Fareed J.
    Thromb Res; 1993 Jan 01; 69(1):59-70. PubMed ID: 8465275
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  • 16. Biological relevance of anti-recombinant hirudin antibodies--results from in vitro and in vivo studies.
    Liebe V, Brückmann M, Fischer KG, Haase KK, Borggrefe M, Huhle G.
    Semin Thromb Hemost; 2002 Oct 01; 28(5):483-90. PubMed ID: 12420244
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  • 18. Nanoscaled polyion complex micelles for targeted delivery of recombinant hirudin to platelets based on cationic copolymer.
    Wang F, Li X, Zhou Y, Zhang Y, Chen X, Yang J, Huang Y, Liu Y.
    Mol Pharm; 2010 Jun 07; 7(3):718-26. PubMed ID: 20349976
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  • 19. Influence of recombinant hirudin on tissue-factor-induced activation of coagulation in rabbits.
    Kouz J, Czech J, Nicolay U, Dickneite G.
    Haemostasis; 1996 Jun 07; 26(4):179-86. PubMed ID: 8872128
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  • 20. Pharmacological survey of recombinant hirudin.
    Markwardt F, Fink G, Kaiser B, Klöcking HP, Nowak G, Richter M, Stürzebecher J.
    Pharmazie; 1988 Mar 07; 43(3):202-7. PubMed ID: 3380865
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