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Journal Abstract Search


229 related items for PubMed ID: 18434359

  • 1. A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis.
    Bujalska IJ, Gathercole LL, Tomlinson JW, Darimont C, Ermolieff J, Fanjul AN, Rejto PA, Stewart PM.
    J Endocrinol; 2008 May; 197(2):297-307. PubMed ID: 18434359
    [Abstract] [Full Text] [Related]

  • 2. Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake.
    McNelis JC, Manolopoulos KN, Gathercole LL, Bujalska IJ, Stewart PM, Tomlinson JW, Arlt W.
    Am J Physiol Endocrinol Metab; 2013 Nov 01; 305(9):E1134-44. PubMed ID: 24022868
    [Abstract] [Full Text] [Related]

  • 3. Preadipocyte 11beta-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo.
    De Sousa Peixoto RA, Turban S, Battle JH, Chapman KE, Seckl JR, Morton NM.
    Endocrinology; 2008 Apr 01; 149(4):1861-8. PubMed ID: 18174284
    [Abstract] [Full Text] [Related]

  • 4. The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy.
    Tomlinson JW, Durrani OM, Bujalska IJ, Gathercole LL, Tomlins PJ, Reuser TT, Rose GE, Curnow SJ, Stewart PM, Walker EA, Rauz S.
    J Clin Endocrinol Metab; 2010 Jan 01; 95(1):398-406. PubMed ID: 19880789
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  • 7. 11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol.
    Bujalska IJ, Walker EA, Tomlinson JW, Hewison M, Stewart PM.
    Endocr Res; 2002 Nov 01; 28(4):449-61. PubMed ID: 12530648
    [Abstract] [Full Text] [Related]

  • 8. 11beta-hydroxysteroid dehydrogenase type 1 and obesity.
    Morton NM, Seckl JR.
    Front Horm Res; 2008 Nov 01; 36():146-164. PubMed ID: 18230901
    [Abstract] [Full Text] [Related]

  • 9. Extra-adrenal regeneration of glucocorticoids by 11beta-hydroxysteroid dehydrogenase type 1: physiological regulator and pharmacological target for energy partitioning.
    Walker BR.
    Proc Nutr Soc; 2007 Feb 01; 66(1):1-8. PubMed ID: 17343766
    [Abstract] [Full Text] [Related]

  • 10. Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis.
    Liu Y, Park F, Pietrusz JL, Jia G, Singh RJ, Netzel BC, Liang M.
    Physiol Genomics; 2008 Feb 19; 32(3):343-51. PubMed ID: 18073273
    [Abstract] [Full Text] [Related]

  • 11. Tissue-specific glucocorticoid reactivating enzyme, 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1)--a promising drug target for the treatment of metabolic syndrome.
    Masuzaki H, Flier JS.
    Curr Drug Targets Immune Endocr Metabol Disord; 2003 Dec 19; 3(4):255-62. PubMed ID: 14683456
    [Abstract] [Full Text] [Related]

  • 12. Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat.
    Bujalska IJ, Durrani OM, Abbott J, Onyimba CU, Khosla P, Moosavi AH, Reuser TT, Stewart PM, Tomlinson JW, Walker EA, Rauz S.
    J Endocrinol; 2007 Feb 19; 192(2):279-88. PubMed ID: 17283228
    [Abstract] [Full Text] [Related]

  • 13. Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.
    Park JS, Rhee SD, Jung WH, Kang NS, Kim HY, Kang SK, Ahn JH, Kim KY.
    Eur J Pharmacol; 2012 Sep 15; 691(1-3):19-27. PubMed ID: 22760069
    [Abstract] [Full Text] [Related]

  • 14. The rise in expression and activity of 11β-HSD1 in human mesenchymal progenitor cells induces adipogenesis through increased local cortisol synthesis.
    Blaschke M, Koepp R, Streit F, Beismann J, Manthey G, Seitz MT, Kragl A, Siggelkow H.
    J Steroid Biochem Mol Biol; 2021 Jun 15; 210():105850. PubMed ID: 33639236
    [Abstract] [Full Text] [Related]

  • 15. An inhibitor of 11-β hydroxysteroid dehydrogenase type 1 (PF915275) alleviates nonylphenol-induced hyperadrenalism and adiposity in rat and human cells.
    Chang LL, Wun WA, Wang PS.
    BMC Pharmacol Toxicol; 2018 Jul 18; 19(1):45. PubMed ID: 30021644
    [Abstract] [Full Text] [Related]

  • 16. Growth hormone (GH) or insulin-like growth factor (IGF)-I represses 11beta-hydroxysteroid dehydrogenase type 1 (HSD1) mRNA expression in 3T3-L1 cells and its activity in their homogenates.
    Morita J, Hakuno F, Hizuka N, Takahashi S, Takano K.
    Endocr J; 2009 Jul 18; 56(4):561-70. PubMed ID: 19352050
    [Abstract] [Full Text] [Related]

  • 17. Identification of a novel 11β-HSD1 inhibitor from a high-throughput screen of natural product extracts.
    Park SB, Park JS, Jung WH, Park A, Jo SR, Kim HY, Dal Rhee S, Ryu SY, Jeong HG, Park S, Lee H, Kim KY.
    Pharmacol Res; 2015 Dec 18; 102():245-53. PubMed ID: 26515507
    [Abstract] [Full Text] [Related]

  • 18. Characterisation of the prereceptor regulation of glucocorticoids in the anterior segment of the rabbit eye.
    Onyimba CU, Vijapurapu N, Curnow SJ, Khosla P, Stewart PM, Murray PI, Walker EA, Rauz S.
    J Endocrinol; 2006 Aug 18; 190(2):483-93. PubMed ID: 16899581
    [Abstract] [Full Text] [Related]

  • 19. Effects of peroxisome proliferator-activated receptor-alpha and -gamma agonists on 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue in men.
    Wake DJ, Stimson RH, Tan GD, Homer NZ, Andrew R, Karpe F, Walker BR.
    J Clin Endocrinol Metab; 2007 May 18; 92(5):1848-56. PubMed ID: 17327378
    [Abstract] [Full Text] [Related]

  • 20. Differential modulation of 3T3-L1 adipogenesis mediated by 11beta-hydroxysteroid dehydrogenase-1 levels.
    Kim J, Temple KA, Jones SA, Meredith KN, Basko JL, Brady MJ.
    J Biol Chem; 2007 Apr 13; 282(15):11038-46. PubMed ID: 17311922
    [Abstract] [Full Text] [Related]


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