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Journal Abstract Search

241 related items for PubMed ID: 18435534

  • 1. Quantitative lid dynamics of MDM2 reveals differential ligand binding modes of the p53-binding cleft.
    Showalter SA, Bruschweiler-Li L, Johnson E, Zhang F, Brüschweiler R.
    J Am Chem Soc; 2008 May 21; 130(20):6472-8. PubMed ID: 18435534
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  • 2. Microsecond simulations of mdm2 and its complex with p53 yield insight into force field accuracy and conformational dynamics.
    Pantelopulos GA, Mukherjee S, Voelz VA.
    Proteins; 2015 Sep 21; 83(9):1665-76. PubMed ID: 26138282
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  • 3. Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamics.
    Verkhivker GM.
    PLoS One; 2012 Sep 21; 7(7):e40897. PubMed ID: 22815859
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  • 4. Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
    Grace CR, Ban D, Min J, Mayasundari A, Min L, Finch KE, Griffiths L, Bharatham N, Bashford D, Kiplin Guy R, Dyer MA, Kriwacki RW.
    J Mol Biol; 2016 Mar 27; 428(6):1290-1303. PubMed ID: 26812210
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  • 11. Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.
    Chee SM, Wongsantichon J, Soo Tng Q, Robinson R, Joseph TL, Verma C, Lane DP, Brown CJ, Ghadessy FJ.
    PLoS One; 2014 Mar 27; 9(8):e104914. PubMed ID: 25115702
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  • 12. Identification of a second Nutlin-3 responsive interaction site in the N-terminal domain of MDM2 using hydrogen/deuterium exchange mass spectrometry.
    Hernychova L, Man P, Verma C, Nicholson J, Sharma CA, Ruckova E, Teo JY, Ball K, Vojtesek B, Hupp TR.
    Proteomics; 2013 Aug 27; 13(16):2512-25. PubMed ID: 23776060
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  • 14. Determinants of specificity of MDM2 for the activation domains of p53 and p65: proline27 disrupts the MDM2-binding motif of p53.
    Zondlo SC, Lee AE, Zondlo NJ.
    Biochemistry; 2006 Oct 03; 45(39):11945-57. PubMed ID: 17002294
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  • 15. Binding induced folding in p53-MDM2 complex.
    Chen HF, Luo R.
    J Am Chem Soc; 2007 Mar 14; 129(10):2930-7. PubMed ID: 17302414
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  • 16. The C terminus of p53 binds the N-terminal domain of MDM2.
    Poyurovsky MV, Katz C, Laptenko O, Beckerman R, Lokshin M, Ahn J, Byeon IJ, Gabizon R, Mattia M, Zupnick A, Brown LM, Friedler A, Prives C.
    Nat Struct Mol Biol; 2010 Aug 14; 17(8):982-9. PubMed ID: 20639885
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  • 17. Efficient reactivation of p53 in cancer cells by a dual MdmX/Mdm2 inhibitor.
    Qin L, Yang F, Zhou C, Chen Y, Zhang H, Su Z.
    J Am Chem Soc; 2014 Dec 31; 136(52):18023-33. PubMed ID: 25453499
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  • 18. The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant.
    Anil B, Riedinger C, Endicott JA, Noble ME.
    Acta Crystallogr D Biol Crystallogr; 2013 Aug 31; 69(Pt 8):1358-66. PubMed ID: 23897459
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  • 19. Molecular mimicry-based repositioning of nutlin-3 to anti-apoptotic Bcl-2 family proteins.
    Ha JH, Won EY, Shin JS, Jang M, Ryu KS, Bae KH, Park SG, Park BC, Yoon HS, Chi SW.
    J Am Chem Soc; 2011 Feb 09; 133(5):1244-7. PubMed ID: 21210687
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  • 20. Flexible lid to the p53-binding domain of human Mdm2: implications for p53 regulation.
    McCoy MA, Gesell JJ, Senior MM, Wyss DF.
    Proc Natl Acad Sci U S A; 2003 Feb 18; 100(4):1645-8. PubMed ID: 12552135
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