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Journal Abstract Search

381 related items for PubMed ID: 18435754

  • 1. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
    Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsia; 2008 Jul; 49(7):1202-12. PubMed ID: 18435754
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
    Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M.
    Epilepsia; 2010 Mar; 51(3):323-32. PubMed ID: 19674061
    [Abstract] [Full Text] [Related]

  • 3. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
    Okada A, Noyori H, Yagen B, Shimshoni JA, Bialer M, Fujiwara M.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Oct; 86(5):394-401. PubMed ID: 19830722
    [Abstract] [Full Text] [Related]

  • 4. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
    Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2009 Apr 23; 52(8):2233-42. PubMed ID: 19296679
    [Abstract] [Full Text] [Related]

  • 5. Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.
    Gravemann U, Volland J, Nau H.
    Neurotoxicol Teratol; 2008 Apr 23; 30(5):390-4. PubMed ID: 18455366
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  • 7. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
    Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M.
    Epilepsy Res; 2007 Jan 23; 73(1):75-84. PubMed ID: 16997532
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  • 9. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
    Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2007 Dec 13; 50(25):6419-27. PubMed ID: 17994680
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives.
    Shimshoni JA, Bialer M, Yagen B.
    Bioorg Med Chem; 2008 Jun 01; 16(11):6297-305. PubMed ID: 18472270
    [Abstract] [Full Text] [Related]

  • 11. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
    Sobol E, Bialer M, Yagen B.
    J Med Chem; 2004 Aug 12; 47(17):4316-26. PubMed ID: 15294003
    [Abstract] [Full Text] [Related]

  • 12. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
    Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.
    Epilepsia; 2014 Dec 12; 55(12):1944-52. PubMed ID: 25442425
    [Abstract] [Full Text] [Related]

  • 13. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.
    Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M.
    Neuropharmacology; 2006 Sep 12; 51(4):933-46. PubMed ID: 16890251
    [Abstract] [Full Text] [Related]

  • 14. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
    Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M.
    Epilepsy Behav; 2011 Nov 12; 22(3):461-8. PubMed ID: 21959082
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
    Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M.
    Neuropharmacology; 2010 Jun 12; 58(8):1228-36. PubMed ID: 20230843
    [Abstract] [Full Text] [Related]

  • 16. Myo-inositol enhances teratogenicity of valproic acid in the mouse.
    Massa V, Wlodarczyk B, Giavini E, Finnell RH.
    Birth Defects Res A Clin Mol Teratol; 2006 Mar 12; 76(3):200-4. PubMed ID: 16511884
    [Abstract] [Full Text] [Related]

  • 17. Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide.
    Hen N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B.
    J Med Chem; 2010 May 27; 53(10):4177-86. PubMed ID: 20420384
    [Abstract] [Full Text] [Related]

  • 18. Preliminary evaluation of the anticonvulsant activity of a valproic acid analog: N-(2-propylpentanoyl) urea.
    Tantisira B, Tantisira MH, Patarapanich C, Sooksawate T, Chunngam T.
    Res Commun Mol Pathol Pharmacol; 1997 Aug 27; 97(2):151-64. PubMed ID: 9344228
    [Abstract] [Full Text] [Related]

  • 19. The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.
    White HS, Franklin MR, Kupferberg HJ, Schmutz M, Stables JP, Wolf HH.
    Epilepsia; 2008 Jul 27; 49(7):1213-20. PubMed ID: 18325020
    [Abstract] [Full Text] [Related]

  • 20. Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
    Isoherranen N, White HS, Finnell RH, Yagen B, Woodhead JH, Bennett GD, Wilcox KS, Barton ME, Bialer M.
    Epilepsia; 2002 Feb 27; 43(2):115-26. PubMed ID: 11903457
    [Abstract] [Full Text] [Related]

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