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Journal Abstract Search

299 related items for PubMed ID: 18439832

  • 1. Synthesis of 3,5-bis(2-indolyl)pyridine and 3-[(2-indolyl)-5-phenyl]pyridine derivatives as CDK inhibitors and cytotoxic agents.
    Jacquemard U, Dias N, Lansiaux A, Bailly C, Logé C, Robert JM, Lozach O, Meijer L, Mérour JY, Routier S.
    Bioorg Med Chem; 2008 May 01; 16(9):4932-53. PubMed ID: 18439832
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of new 3-(6-hydroxyindol-2-yl)-5-(Phenyl) pyridine or pyrazine V-Shaped molecules as kinase inhibitors and cytotoxic agents.
    Kassis P, Brzeszcz J, Bénéteau V, Lozach O, Meijer L, Le Guével R, Guillouzo C, Lewiński K, Bourg S, Colliandre L, Routier S, Mérour JY.
    Eur J Med Chem; 2011 Nov 01; 46(11):5416-34. PubMed ID: 21944287
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents.
    Lin R, Connolly PJ, Lu Y, Chiu G, Li S, Yu Y, Huang S, Li X, Emanuel SL, Middleton SA, Gruninger RH, Adams M, Fuentes-Pesquera AR, Greenberger LM.
    Bioorg Med Chem Lett; 2007 Aug 01; 17(15):4297-302. PubMed ID: 17532631
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.
    Hayakawa M, Kaizawa H, Kawaguchi K, Ishikawa N, Koizumi T, Ohishi T, Yamano M, Okada M, Ohta M, Tsukamoto S, Raynaud FI, Waterfield MD, Parker P, Workman P.
    Bioorg Med Chem; 2007 Jan 01; 15(1):403-12. PubMed ID: 17049248
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
    Ye Q, Cao J, Zhou X, Lv D, He Q, Yang B, Hu Y.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4763-72. PubMed ID: 19447039
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors.
    Hayakawa M, Kawaguchi K, Kaizawa H, Koizumi T, Ohishi T, Yamano M, Okada M, Ohta M, Tsukamoto S, Raynaud FI, Parker P, Workman P, Waterfield MD.
    Bioorg Med Chem; 2007 Sep 01; 15(17):5837-44. PubMed ID: 17601739
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.
    Abadi AH, Abou-Seri SM, Abdel-Rahman DE, Klein C, Lozach O, Meijer L.
    Eur J Med Chem; 2006 Mar 01; 41(3):296-305. PubMed ID: 16494969
    [Abstract] [Full Text] [Related]

  • 8. Cell division cycle 7 kinase inhibitors: 1H-pyrrolo[2,3-b]pyridines, synthesis and structure-activity relationships.
    Ermoli A, Bargiotti A, Brasca MG, Ciavolella A, Colombo N, Fachin G, Isacchi A, Menichincheri M, Molinari A, Montagnoli A, Pillan A, Rainoldi S, Sirtori FR, Sola F, Thieffine S, Tibolla M, Valsasina B, Volpi D, Santocanale C, Vanotti E.
    J Med Chem; 2009 Jul 23; 52(14):4380-90. PubMed ID: 19555113
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and activity of quinolinyl-methylene-thiazolinones as potent and selective cyclin-dependent kinase 1 inhibitors.
    Chen S, Chen L, Le NT, Zhao C, Sidduri A, Lou JP, Michoud C, Portland L, Jackson N, Liu JJ, Konzelmann F, Chi F, Tovar C, Xiang Q, Chen Y, Wen Y, Vassilev LT.
    Bioorg Med Chem Lett; 2007 Apr 15; 17(8):2134-8. PubMed ID: 17303421
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents.
    Routier S, Peixoto P, Mérour JY, Coudert G, Dias N, Bailly C, Pierré A, Léonce S, Caignard DH.
    J Med Chem; 2005 Mar 10; 48(5):1401-13. PubMed ID: 15743184
    [Abstract] [Full Text] [Related]

  • 11. N-(indazolyl)benzamido derivatives as CDK1 inhibitors: design, synthesis, biological activity, and molecular docking studies.
    Raffa D, Maggio B, Cascioferro S, Raimondi MV, Daidone G, Plescia S, Schillaci D, Cusimano MG, Titone L, Colomba C, Tolomeo M.
    Arch Pharm (Weinheim); 2009 May 10; 342(5):265-73. PubMed ID: 19415659
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and identification of [1,3,5]triazine-pyridine biheteroaryl as a novel series of potent cyclin-dependent kinase inhibitors.
    Kuo GH, Deangelis A, Emanuel S, Wang A, Zhang Y, Connolly PJ, Chen X, Gruninger RH, Rugg C, Fuentes-Pesquera A, Middleton SA, Jolliffe L, Murray WV.
    J Med Chem; 2005 Jul 14; 48(14):4535-46. PubMed ID: 15999992
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of 2-amino-4-(7-azaindol-3-yl)pyrimidines as cyclin dependent kinase 1 (CDK1) inhibitors.
    Huang S, Li R, Connolly PJ, Emanuel S, Middleton SA.
    Bioorg Med Chem Lett; 2006 Sep 15; 16(18):4818-21. PubMed ID: 16870444
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo[1,2-b]pyridine, a potent cyclin dependent kinase 1 (CDK1) inhibitor.
    Huang S, Lin R, Yu Y, Lu Y, Connolly PJ, Chiu G, Li S, Emanuel SL, Middleton SA.
    Bioorg Med Chem Lett; 2007 Mar 01; 17(5):1243-5. PubMed ID: 17234412
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors.
    Woods KW, Fischer JP, Claiborne A, Li T, Thomas SA, Zhu GD, Diebold RB, Liu X, Shi Y, Klinghofer V, Han EK, Guan R, Magnone SR, Johnson EF, Bouska JJ, Olson AM, de Jong R, Oltersdorf T, Luo Y, Rosenberg SH, Giranda VL, Li Q.
    Bioorg Med Chem; 2006 Oct 15; 14(20):6832-46. PubMed ID: 16843670
    [Abstract] [Full Text] [Related]

  • 16. Efficient synthesis of 6-(hetero)arylthieno[3,2-b]pyridines by Suzuki-Miyaura coupling. Evaluation of growth inhibition on human tumor cell lines, SARs and effects on the cell cycle.
    Queiroz MJ, Calhelha RC, Vale-Silva LA, Pinto E, Lima RT, Vasconcelos MH.
    Eur J Med Chem; 2010 Dec 15; 45(12):5628-34. PubMed ID: 20926160
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.
    Marhadour S, Marchand P, Pagniez F, Bazin MA, Picot C, Lozach O, Ruchaud S, Antoine M, Meijer L, Rachidi N, Le Pape P.
    Eur J Med Chem; 2012 Dec 15; 58():543-56. PubMed ID: 23164660
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and PKCtheta inhibitory activity of a series of 5-vinyl phenyl sulfonamide-3-pyridinecarbonitriles.
    Shim J, Eid C, Lee J, Liu E, Chaudhary D, Boschelli DH.
    Bioorg Med Chem Lett; 2009 Dec 01; 19(23):6575-7. PubMed ID: 19854645
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, biological evaluation and molecular docking studies of amide-coupled benzoic nitrogen mustard derivatives as potential antitumor agents.
    Zheng QZ, Zhang F, Cheng K, Yang Y, Chen Y, Qian Y, Zhang HJ, Li HQ, Zhou CF, An SQ, Jiao QC, Zhu HL.
    Bioorg Med Chem; 2010 Jan 15; 18(2):880-6. PubMed ID: 20005116
    [Abstract] [Full Text] [Related]

  • 20. Antitumor agents. 5. synthesis, structure-activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5h-benzopyridophenoxazin-5-ones, and 5h-benzopyridophenoxazin-5-ones with potent antiproliferative activity.
    Bolognese A, Correale G, Manfra M, Lavecchia A, Novellino E, Pepe S.
    J Med Chem; 2006 Aug 24; 49(17):5110-8. PubMed ID: 16913700
    [Abstract] [Full Text] [Related]

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