These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

165 related items for PubMed ID: 18439847

  • 1. The role of 23S ribosomal RNA residue A2451 in peptide bond synthesis revealed by atomic mutagenesis.
    Lang K, Erlacher M, Wilson DN, Micura R, Polacek N.
    Chem Biol; 2008 May; 15(5):485-92. PubMed ID: 18439847
    [Abstract] [Full Text] [Related]

  • 2. Efficient ribosomal peptidyl transfer critically relies on the presence of the ribose 2'-OH at A2451 of 23S rRNA.
    Erlacher MD, Lang K, Wotzel B, Rieder R, Micura R, Polacek N.
    J Am Chem Soc; 2006 Apr 05; 128(13):4453-9. PubMed ID: 16569023
    [Abstract] [Full Text] [Related]

  • 3. Chemical engineering of the peptidyl transferase center reveals an important role of the 2'-hydroxyl group of A2451.
    Erlacher MD, Lang K, Shankaran N, Wotzel B, Hüttenhofer A, Micura R, Mankin AS, Polacek N.
    Nucleic Acids Res; 2005 Apr 05; 33(5):1618-27. PubMed ID: 15767286
    [Abstract] [Full Text] [Related]

  • 4. The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.
    Polacek N, Gomez MJ, Ito K, Xiong L, Nakamura Y, Mankin A.
    Mol Cell; 2003 Jan 05; 11(1):103-12. PubMed ID: 12535525
    [Abstract] [Full Text] [Related]

  • 5. Ribosomal peptidyl transferase can withstand mutations at the putative catalytic nucleotide.
    Polacek N, Gaynor M, Yassin A, Mankin AS.
    Nature; 2001 May 24; 411(6836):498-501. PubMed ID: 11373685
    [Abstract] [Full Text] [Related]

  • 6. An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination.
    Amort M, Wotzel B, Bakowska-Zywicka K, Erlacher MD, Micura R, Polacek N.
    Nucleic Acids Res; 2007 May 24; 35(15):5130-40. PubMed ID: 17660192
    [Abstract] [Full Text] [Related]

  • 7. 23S rRNA positions essential for tRNA binding in ribosomal functional sites.
    Bocchetta M, Xiong L, Mankin AS.
    Proc Natl Acad Sci U S A; 1998 Mar 31; 95(7):3525-30. PubMed ID: 9520399
    [Abstract] [Full Text] [Related]

  • 8. The role of the universally conserved A2450-C2063 base pair in the ribosomal peptidyl transferase center.
    Chirkova A, Erlacher MD, Clementi N, Zywicki M, Aigner M, Polacek N.
    Nucleic Acids Res; 2010 Aug 31; 38(14):4844-55. PubMed ID: 20375101
    [Abstract] [Full Text] [Related]

  • 9. pH-dependent conformational flexibility within the ribosomal peptidyl transferase center.
    Muth GW, Chen L, Kosek AB, Strobel SA.
    RNA; 2001 Oct 31; 7(10):1403-15. PubMed ID: 11680845
    [Abstract] [Full Text] [Related]

  • 10. pKa of adenine 2451 in the ribosomal peptidyl transferase center remains elusive.
    Xiong L, Polacek N, Sander P, Böttger EC, Mankin A.
    RNA; 2001 Oct 31; 7(10):1365-9. PubMed ID: 11680840
    [Abstract] [Full Text] [Related]

  • 11. Analysis of mutations at residues A2451 and G2447 of 23S rRNA in the peptidyltransferase active site of the 50S ribosomal subunit.
    Thompson J, Kim DF, O'Connor M, Lieberman KR, Bayfield MA, Gregory ST, Green R, Noller HF, Dahlberg AE.
    Proc Natl Acad Sci U S A; 2001 Jul 31; 98(16):9002-7. PubMed ID: 11470897
    [Abstract] [Full Text] [Related]

  • 12. 23S rRNA similarity from selection for peptidyl transferase mimicry.
    Welch M, Majerfeld I, Yarus M.
    Biochemistry; 1997 Jun 03; 36(22):6614-23. PubMed ID: 9184141
    [Abstract] [Full Text] [Related]

  • 13. A single adenosine with a neutral pKa in the ribosomal peptidyl transferase center.
    Muth GW, Ortoleva-Donnelly L, Strobel SA.
    Science; 2000 Aug 11; 289(5481):947-50. PubMed ID: 10937997
    [Abstract] [Full Text] [Related]

  • 14. The structural basis of ribosome activity in peptide bond synthesis.
    Nissen P, Hansen J, Ban N, Moore PB, Steitz TA.
    Science; 2000 Aug 11; 289(5481):920-30. PubMed ID: 10937990
    [Abstract] [Full Text] [Related]

  • 15. A base pair between tRNA and 23S rRNA in the peptidyl transferase centre of the ribosome.
    Samaha RR, Green R, Noller HF.
    Nature; 1995 Sep 28; 377(6547):309-14. PubMed ID: 7566085
    [Abstract] [Full Text] [Related]

  • 16. Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
    Jin H, Kelley AC, Loakes D, Ramakrishnan V.
    Proc Natl Acad Sci U S A; 2010 May 11; 107(19):8593-8. PubMed ID: 20421507
    [Abstract] [Full Text] [Related]

  • 17. Exploration of the conserved A+C wobble pair within the ribosomal peptidyl transferase center using affinity purified mutant ribosomes.
    Hesslein AE, Katunin VI, Beringer M, Kosek AB, Rodnina MV, Strobel SA.
    Nucleic Acids Res; 2004 May 11; 32(12):3760-70. PubMed ID: 15256541
    [Abstract] [Full Text] [Related]

  • 18. Mutational analysis of the donor substrate binding site of the ribosomal peptidyltransferase center.
    Saarma U, Spahn CM, Nierhaus KH, Remme J.
    RNA; 1998 Feb 11; 4(2):189-94. PubMed ID: 9570318
    [Abstract] [Full Text] [Related]

  • 19. Mutations in the conserved P loop perturb the conformation of two structural elements in the peptidyl transferase center of 23 S ribosomal RNA.
    Gregory ST, Dahlberg AE.
    J Mol Biol; 1999 Jan 29; 285(4):1475-83. PubMed ID: 9917390
    [Abstract] [Full Text] [Related]

  • 20. Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation.
    Clementi N, Chirkova A, Puffer B, Micura R, Polacek N.
    Nat Chem Biol; 2010 May 29; 6(5):344-51. PubMed ID: 20348921
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 9.