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83 related items for PubMed ID: 18440561

  • 1. Activation of C-transactivation domain is essential for optimal HIF-1 alpha-mediated transcriptional and angiogenic effects.
    Tal R, Shaish A, Bangio L, Peled M, Breitbart E, Harats D.
    Microvasc Res; 2008 May; 76(1):1-6. PubMed ID: 18440561
    [Abstract] [Full Text] [Related]

  • 2. Activation of hypoxia-induced transcription in normoxia.
    Hägg M, Wennström S.
    Exp Cell Res; 2005 May 15; 306(1):180-91. PubMed ID: 15878343
    [Abstract] [Full Text] [Related]

  • 3. Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression.
    Jensen RL, Gillespie D, House P, Layfield L, Shelton C.
    J Neurosurg; 2004 Mar 15; 100(3):488-97. PubMed ID: 15035285
    [Abstract] [Full Text] [Related]

  • 4. Cisplatin and doxorubicin repress Vascular Endothelial Growth Factor expression and differentially down-regulate Hypoxia-inducible Factor I activity in human ovarian cancer cells.
    Duyndam MC, van Berkel MP, Dorsman JC, Rockx DA, Pinedo HM, Boven E.
    Biochem Pharmacol; 2007 Jul 15; 74(2):191-201. PubMed ID: 17498666
    [Abstract] [Full Text] [Related]

  • 5. Src induces expression of carbonic anhydrase IX via hypoxia-inducible factor 1.
    Takacova M, Holotnakova T, Barathova M, Pastorekova S, Kopacek J, Pastorek J.
    Oncol Rep; 2010 Mar 15; 23(3):869-74. PubMed ID: 20127031
    [Abstract] [Full Text] [Related]

  • 6. Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1alpha.
    Lee YM, Lim JH, Chun YS, Moon HE, Lee MK, Huang LE, Park JW.
    Carcinogenesis; 2009 Oct 15; 30(10):1768-75. PubMed ID: 19696166
    [Abstract] [Full Text] [Related]

  • 7. Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein.
    Tanimoto K, Makino Y, Pereira T, Poellinger L.
    EMBO J; 2000 Aug 15; 19(16):4298-309. PubMed ID: 10944113
    [Abstract] [Full Text] [Related]

  • 8. FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity.
    Mahon PC, Hirota K, Semenza GL.
    Genes Dev; 2001 Oct 15; 15(20):2675-86. PubMed ID: 11641274
    [Abstract] [Full Text] [Related]

  • 9. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 10. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F, Roux D, Brahimi-Horn MC, Pouyssegur J, Mazure NM.
    Cancer Res; 2006 Apr 01; 66(7):3688-98. PubMed ID: 16585195
    [Abstract] [Full Text] [Related]

  • 11. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
    Shinojima T, Oya M, Takayanagi A, Mizuno R, Shimizu N, Murai M.
    Carcinogenesis; 2007 Mar 01; 28(3):529-36. PubMed ID: 16920734
    [Abstract] [Full Text] [Related]

  • 12. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC, Lee CF, Huang WH, Chou TC.
    Biochem Pharmacol; 2013 May 01; 85(9):1278-87. PubMed ID: 23416116
    [Abstract] [Full Text] [Related]

  • 13. Mutant hypoxia inducible factor-1α improves angiogenesis and tissue perfusion in ischemic rabbit skeletal muscle.
    Li M, Liu C, Bin J, Wang Y, Chen J, Xiu J, Pei J, Lai Y, Chen D, Fan C, Xie J, Tao Y, Wu P.
    Microvasc Res; 2011 Jan 01; 81(1):26-33. PubMed ID: 20937289
    [Abstract] [Full Text] [Related]

  • 14. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.
    Rapisarda A, Uranchimeg B, Scudiero DA, Selby M, Sausville EA, Shoemaker RH, Melillo G.
    Cancer Res; 2002 Aug 01; 62(15):4316-24. PubMed ID: 12154035
    [Abstract] [Full Text] [Related]

  • 15. PI3K/Akt activity has variable cell-specific effects on expression of HIF target genes, CA9 and VEGF, in human cancer cell lines.
    Shafee N, Kaluz S, Ru N, Stanbridge EJ.
    Cancer Lett; 2009 Sep 08; 282(1):109-15. PubMed ID: 19342157
    [Abstract] [Full Text] [Related]

  • 16. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 17. 6-Mercaptopurine, an activator of Nur77, enhances transcriptional activity of HIF-1alpha resulting in new vessel formation.
    Yoo YG, Na TY, Yang WK, Kim HJ, Lee IK, Kong G, Chung JH, Lee MO.
    Oncogene; 2007 May 31; 26(26):3823-34. PubMed ID: 17146432
    [Abstract] [Full Text] [Related]

  • 18. Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma.
    Maranchie JK, Zhan Y.
    Cancer Res; 2005 Oct 15; 65(20):9190-3. PubMed ID: 16230378
    [Abstract] [Full Text] [Related]

  • 19. Antisense-thioredoxin inhibits angiogenesis via pVHL-mediated hypoxia-inducible factor-1alpha degradation.
    Kim WJ, Cho H, Lee SW, Kim YJ, Kim KW.
    Int J Oncol; 2005 Apr 15; 26(4):1049-52. PubMed ID: 15754001
    [Abstract] [Full Text] [Related]

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