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173 related items for PubMed ID: 18442916

  • 1. Aged wild-type and APP, PS1, and APP + PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load.
    Gruart A, López-Ramos JC, Muñoz MD, Delgado-García JM.
    Neurobiol Dis; 2008 Jun; 30(3):439-450. PubMed ID: 18442916
    [Abstract] [Full Text] [Related]

  • 2. Impairment of Spike-Timing-Dependent Plasticity at Schaffer Collateral-CA1 Synapses in Adult APP/PS1 Mice Depends on Proximity of Aβ Plaques.
    Garad M, Edelmann E, Leßmann V.
    Int J Mol Sci; 2021 Jan 30; 22(3):. PubMed ID: 33573114
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  • 3. Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis.
    Scullion GA, Kendall DA, Marsden CA, Sunter D, Pardon MC.
    Neuropharmacology; 2011 Jan 30; 60(2-3):223-34. PubMed ID: 20850464
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  • 4. The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.
    Collins JM, King AE, Woodhouse A, Kirkcaldie MT, Vickers JC.
    Exp Neurol; 2015 May 30; 267():219-29. PubMed ID: 25747037
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  • 5. Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
    Dewachter I, Reversé D, Caluwaerts N, Ris L, Kuipéri C, Van den Haute C, Spittaels K, Umans L, Serneels L, Thiry E, Moechars D, Mercken M, Godaux E, Van Leuven F.
    J Neurosci; 2002 May 01; 22(9):3445-53. PubMed ID: 11978821
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  • 6. Muscone Ameliorates Synaptic Dysfunction and Cognitive Deficits in APP/PS1 Mice.
    Liu Y, Bian H, Xu S, Shu S, Jia J, Chen J, Cao X, Bao X, Gu Y, Xia S, Yang H, Yu L, Xu Y, Zhu X.
    J Alzheimers Dis; 2020 May 01; 76(2):491-504. PubMed ID: 32538849
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  • 7. An in vitro and in vivo study of early deficits in associative learning in transgenic mice that over-express a mutant form of human APP associated with Alzheimer's disease.
    Domínguez-del-Toro E, Rodríguez-Moreno A, Porras-García E, Sánchez-Campusano R, Blanchard V, Laville M, Böhme GA, Benavides J, Delgado-García JM.
    Eur J Neurosci; 2004 Oct 01; 20(7):1945-52. PubMed ID: 15380017
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  • 8. Treadmill exercise enhances synaptic plasticity, but does not alter β-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice.
    Zhao G, Liu HL, Zhang H, Tong XJ.
    Neuroscience; 2015 Jul 09; 298():357-66. PubMed ID: 25917310
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  • 10. Cognitive deficits associated with alteration of synaptic metaplasticity precede plaque deposition in AβPP23 transgenic mice.
    Balducci C, Tonini R, Zianni E, Nazzaro C, Fiordaliso F, Salio M, Vismara L, Gardoni F, Di Luca M, Carli M, Forloni G.
    J Alzheimers Dis; 2010 Jul 09; 21(4):1367-81. PubMed ID: 21504138
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  • 11. Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
    Shi Q, Chowdhury S, Ma R, Le KX, Hong S, Caldarone BJ, Stevens B, Lemere CA.
    Sci Transl Med; 2017 May 31; 9(392):. PubMed ID: 28566429
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  • 14. Effects of accelerated senescence on learning and memory, locomotion and anxiety-like behavior in APP/PS1 mouse model of Alzheimer's disease.
    Lok K, Zhao H, Zhang C, He N, Shen H, Wang Z, Zhao W, Yin M.
    J Neurol Sci; 2013 Dec 15; 335(1-2):145-54. PubMed ID: 24095271
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  • 15. Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.
    Hansen HH, Fabricius K, Barkholt P, Kongsbak-Wismann P, Schlumberger C, Jelsing J, Terwel D, Termont A, Pyke C, Knudsen LB, Vrang N.
    PLoS One; 2016 Dec 15; 11(7):e0158205. PubMed ID: 27421117
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  • 17. Age-dependent disruption in hippocampal θ oscillation in amyloid-β overproducing transgenic mice.
    Scott L, Feng J, Kiss T, Needle E, Atchison K, Kawabe TT, Milici AJ, Hajós-Korcsok E, Riddell D, Hajós M.
    Neurobiol Aging; 2012 Jul 15; 33(7):1481.e13-23. PubMed ID: 22227005
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  • 18. DL0410 can reverse cognitive impairment, synaptic loss and reduce plaque load in APP/PS1 transgenic mice.
    Yang RY, Zhao G, Wang DM, Pang XC, Wang SB, Fang JS, Li C, Liu AL, Wu S, Du GH.
    Pharmacol Biochem Behav; 2015 Dec 15; 139(Pt A):15-26. PubMed ID: 26476132
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  • 20. Decreased circadian fluctuation in cognitive behaviors and synaptic plasticity in APP/PS1 transgenic mice.
    He Y, Li Y, Zhou F, Qi J, Wu M.
    Metab Brain Dis; 2020 Feb 15; 35(2):343-352. PubMed ID: 31879834
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