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540 related items for PubMed ID: 18445767

  • 1. Multiple molecular pathways are involved in the neuroprotection of GDNF against proteasome inhibitor induced dopamine neuron degeneration in vivo.
    Du Y, Li X, Yang D, Zhang X, Chen S, Huang K, Le W.
    Exp Biol Med (Maywood); 2008 Jul; 233(7):881-90. PubMed ID: 18445767
    [Abstract] [Full Text] [Related]

  • 2. Proteasome inhibition modeling nigral neuron degeneration in Parkinson's disease.
    Xie W, Li X, Li C, Zhu W, Jankovic J, Le W.
    J Neurochem; 2010 Oct; 115(1):188-99. PubMed ID: 20649845
    [Abstract] [Full Text] [Related]

  • 3. Adeno-associated virus type 2 vector-mediated glial cell line-derived neurotrophic factor gene transfer induces neuroprotection and neuroregeneration in a ubiquitin-proteasome system impairment animal model of Parkinson's disease.
    Du Y, Zhang X, Tao Q, Chen S, Le W.
    Neurodegener Dis; 2013 Oct; 11(3):113-28. PubMed ID: 22626907
    [Abstract] [Full Text] [Related]

  • 4. Genetic iron chelation protects against proteasome inhibition-induced dopamine neuron degeneration.
    Zhu W, Li X, Xie W, Luo F, Kaur D, Andersen JK, Jankovic J, Le W.
    Neurobiol Dis; 2010 Feb; 37(2):307-13. PubMed ID: 19818853
    [Abstract] [Full Text] [Related]

  • 5. Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-kappaB signaling pathway.
    Wang HJ, Cao JP, Yu JK, Zhang LC, Jiang ZJ, Gao DS.
    Eur J Pharmacol; 2008 Oct 24; 595(1-3):7-12. PubMed ID: 18703048
    [Abstract] [Full Text] [Related]

  • 6. Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration.
    Zhang X, Xie W, Qu S, Pan T, Wang X, Le W.
    Biochem Biophys Res Commun; 2005 Jul 29; 333(2):544-9. PubMed ID: 15950935
    [Abstract] [Full Text] [Related]

  • 7. Striatal GDNF administration increases tyrosine hydroxylase phosphorylation in the rat striatum and substantia nigra.
    Salvatore MF, Zhang JL, Large DM, Wilson PE, Gash CR, Thomas TC, Haycock JW, Bing G, Stanford JA, Gash DM, Gerhardt GA.
    J Neurochem; 2004 Jul 29; 90(1):245-54. PubMed ID: 15198683
    [Abstract] [Full Text] [Related]

  • 8. Brain-derived growth factor and glial cell line-derived growth factor use distinct intracellular signaling pathways to protect PD cybrids from H2O2-induced neuronal death.
    Onyango IG, Tuttle JB, Bennett JP.
    Neurobiol Dis; 2005 Oct 29; 20(1):141-54. PubMed ID: 16137575
    [Abstract] [Full Text] [Related]

  • 9. Catalpol attenuates MPTP induced neuronal degeneration of nigral-striatal dopaminergic pathway in mice through elevating glial cell derived neurotrophic factor in striatum.
    Xu G, Xiong Z, Yong Y, Wang Z, Ke Z, Xia Z, Hu Y.
    Neuroscience; 2010 Apr 28; 167(1):174-84. PubMed ID: 20123001
    [Abstract] [Full Text] [Related]

  • 10. Glial-derived neurotrophic factor (GDNF) prevents ethanol (EtOH) induced B92 glial cell death by both PI3K/AKT and MEK/ERK signaling pathways.
    Villegas SN, Njaine B, Linden R, Carri NG.
    Brain Res Bull; 2006 Dec 11; 71(1-3):116-26. PubMed ID: 17113937
    [Abstract] [Full Text] [Related]

  • 11. Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat.
    Connor B, Kozlowski DA, Schallert T, Tillerson JL, Davidson BL, Bohn MC.
    Gene Ther; 1999 Dec 11; 6(12):1936-51. PubMed ID: 10637445
    [Abstract] [Full Text] [Related]

  • 12. GDNF prevents TGF-beta-induced damage of the plasma membrane in cerebellar granule neurons by suppressing activation of p38-MAPK via the phosphatidylinositol 3-kinase pathway.
    Subramaniam S, Strelau J, Unsicker K.
    Cell Tissue Res; 2008 Feb 11; 331(2):373-83. PubMed ID: 18071753
    [Abstract] [Full Text] [Related]

  • 13. Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease.
    Mandel RJ, Snyder RO, Leff SE.
    Exp Neurol; 1999 Nov 11; 160(1):205-14. PubMed ID: 10630205
    [Abstract] [Full Text] [Related]

  • 14. Proteasome inhibitor lactacystin disturbs the intracellular calcium homeostasis of dopamine neurons in ventral mesencephalic cultures.
    Li X, Yang D, Li L, Peng C, Chen S, Le W.
    Neurochem Int; 2007 Jun 11; 50(7-8):959-65. PubMed ID: 17561309
    [Abstract] [Full Text] [Related]

  • 15. Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators.
    Zhu W, Xie W, Pan T, Xu P, Fridkin M, Zheng H, Jankovic J, Youdim MB, Le W.
    FASEB J; 2007 Dec 11; 21(14):3835-44. PubMed ID: 17690154
    [Abstract] [Full Text] [Related]

  • 16. Astrocyte delivery of glial cell line-derived neurotrophic factor in a mouse model of Parkinson's disease.
    Cunningham LA, Su C.
    Exp Neurol; 2002 Apr 11; 174(2):230-42. PubMed ID: 11922664
    [Abstract] [Full Text] [Related]

  • 17. Characterization of organotypic ventral mesencephalic cultures from embryonic mice and protection against MPP toxicity by GDNF.
    Jakobsen B, Gramsbergen JB, Møller Dall A, Rosenblad C, Zimmer J.
    Eur J Neurosci; 2005 Jun 11; 21(11):2939-48. PubMed ID: 15978005
    [Abstract] [Full Text] [Related]

  • 18. The involvement of NF-kappaB p65/p52 in the effects of GDNF on DA neurons in early PD rats.
    Cao JP, Wang HJ, Yu JK, Liu HM, Gao DS.
    Brain Res Bull; 2008 Jul 30; 76(5):505-11. PubMed ID: 18534259
    [Abstract] [Full Text] [Related]

  • 19. Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons.
    Piltonen M, Bespalov MM, Ervasti D, Matilainen T, Sidorova YA, Rauvala H, Saarma M, Männistö PT.
    Exp Neurol; 2009 Oct 30; 219(2):499-506. PubMed ID: 19615368
    [Abstract] [Full Text] [Related]

  • 20. Molecular mechanism of the neurotrophic effect of GDNF on DA neurons: role of protein kinase CK2.
    Chao CC, Chiang CH, Ma YL, Lee EH.
    Neurobiol Aging; 2006 Jan 30; 27(1):105-18. PubMed ID: 16298246
    [Abstract] [Full Text] [Related]

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