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216 related items for PubMed ID: 18448868

  • 1. SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia.
    Ngo HT, Leleu X, Lee J, Jia X, Melhem M, Runnels J, Moreau AS, Burwick N, Azab AK, Roccaro A, Azab F, Sacco A, Farag M, Sackstein R, Ghobrial IM.
    Blood; 2008 Jul 01; 112(1):150-8. PubMed ID: 18448868
    [Abstract] [Full Text] [Related]

  • 2. Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-dependent adhesion to fibronectin and VCAM-1 on bone marrow hematopoietic progenitor cells.
    Hidalgo A, Sanz-Rodríguez F, Rodríguez-Fernández JL, Albella B, Blaya C, Wright N, Cabañas C, Prósper F, Gutierrez-Ramos JC, Teixidó J.
    Exp Hematol; 2001 Mar 01; 29(3):345-55. PubMed ID: 11274763
    [Abstract] [Full Text] [Related]

  • 3. Crosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow.
    Petty JM, Lenox CC, Weiss DJ, Poynter ME, Suratt BT.
    J Immunol; 2009 Jan 01; 182(1):604-12. PubMed ID: 19109194
    [Abstract] [Full Text] [Related]

  • 4. Chemokine stromal cell-derived factor-1alpha modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1.
    Sanz-Rodríguez F, Hidalgo A, Teixidó J.
    Blood; 2001 Jan 15; 97(2):346-51. PubMed ID: 11154207
    [Abstract] [Full Text] [Related]

  • 5. Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
    Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Côté D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM.
    Blood; 2007 Apr 01; 109(7):2708-17. PubMed ID: 17119115
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  • 6. Mobilization of myeloma cells involves SDF-1/CXCR4 signaling and downregulation of VLA-4.
    Gazitt Y, Akay C.
    Stem Cells; 2004 Apr 01; 22(1):65-73. PubMed ID: 14688392
    [Abstract] [Full Text] [Related]

  • 7. Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): importance for interactions with the stromal microenvironment and specific targeting.
    Kurtova AV, Tamayo AT, Ford RJ, Burger JA.
    Blood; 2009 May 07; 113(19):4604-13. PubMed ID: 19228923
    [Abstract] [Full Text] [Related]

  • 8. Hypoxia promotes dissemination and colonization in new bone marrow niches in Waldenström macroglobulinemia.
    Muz B, de la Puente P, Azab F, Ghobrial IM, Azab AK.
    Mol Cancer Res; 2015 Feb 07; 13(2):263-72. PubMed ID: 25232031
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  • 11. Migration of human umbilical cord blood mesenchymal stem cells mediated by stromal cell-derived factor-1/CXCR4 axis via Akt, ERK, and p38 signal transduction pathways.
    Ryu CH, Park SA, Kim SM, Lim JY, Jeong CH, Jun JA, Oh JH, Park SH, Oh WI, Jeun SS.
    Biochem Biophys Res Commun; 2010 Jul 16; 398(1):105-10. PubMed ID: 20558135
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  • 15. Integrin alpha4beta1 involvement in stromal cell-derived factor-1alpha-promoted myeloma cell transendothelial migration and adhesion: role of cAMP and the actin cytoskeleton in adhesion.
    Parmo-Cabañas M, Bartolomé RA, Wright N, Hidalgo A, Drager AM, Teixidó J.
    Exp Cell Res; 2004 Apr 01; 294(2):571-80. PubMed ID: 15023543
    [Abstract] [Full Text] [Related]

  • 16. The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow.
    Shen W, Bendall LJ, Gottlieb DJ, Bradstock KF.
    Exp Hematol; 2001 Dec 01; 29(12):1439-47. PubMed ID: 11750103
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  • 17. CXCR4-targeted PET imaging using 64Cu-AMD3100 for detection of Waldenström Macroglobulinemia.
    Muz B, Bandara N, Mpoy C, Sun J, Alhallak K, Azab F, Rogers BE, Azab AK.
    Cancer Biol Ther; 2020 Dec 01; 21(1):52-60. PubMed ID: 31571524
    [Abstract] [Full Text] [Related]

  • 18. Targeting survival and cell trafficking in multiple myeloma and Waldenstrom macroglobulinemia using pan-class I PI3K inhibitor, buparlisib.
    Sahin I, Azab F, Mishima Y, Moschetta M, Tsang B, Glavey SV, Manier S, Zhang Y, Sacco A, Roccaro AM, Azab AK, Ghobrial IM.
    Am J Hematol; 2014 Nov 01; 89(11):1030-6. PubMed ID: 25060991
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  • 20. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
    Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson AL, Alt C, Burwick N, Roccaro AM, Ngo HT, Farag M, Melhem MR, Sacco A, Munshi NC, Hideshima T, Rollins BJ, Anderson KC, Kung AL, Lin CP, Ghobrial IM.
    Blood; 2009 Apr 30; 113(18):4341-51. PubMed ID: 19139079
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