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Journal Abstract Search

232 related items for PubMed ID: 18459944

  • 1. Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.
    Olearczyk JJ, Quigley JE, Mitchell BC, Yamamoto T, Kim IH, Newman JW, Luria A, Hammock BD, Imig JD.
    Clin Sci (Lond); 2009 Jan; 116(1):61-70. PubMed ID: 18459944
    [Abstract] [Full Text] [Related]

  • 2. An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats.
    Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD.
    J Cardiovasc Pharmacol; 2005 Dec; 46(6):842-8. PubMed ID: 16306811
    [Abstract] [Full Text] [Related]

  • 3. Targeting arachidonic acid pathway to prevent programmed hypertension in maternal fructose-fed male adult rat offspring.
    Tain YL, Lee WC, Wu KLH, Leu S, Chan JYH.
    J Nutr Biochem; 2016 Dec; 38():86-92. PubMed ID: 27732913
    [Abstract] [Full Text] [Related]

  • 4. Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension.
    Li J, Carroll MA, Chander PN, Falck JR, Sangras B, Stier CT.
    Front Biosci; 2008 May 01; 13():3480-7. PubMed ID: 18508449
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  • 5. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension.
    Imig JD, Zhao X, Zaharis CZ, Olearczyk JJ, Pollock DM, Newman JW, Kim IH, Watanabe T, Hammock BD.
    Hypertension; 2005 Oct 01; 46(4):975-81. PubMed ID: 16157792
    [Abstract] [Full Text] [Related]

  • 6. Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels.
    Olearczyk JJ, Field MB, Kim IH, Morisseau C, Hammock BD, Imig JD.
    J Pharmacol Exp Ther; 2006 Sep 01; 318(3):1307-14. PubMed ID: 16772540
    [Abstract] [Full Text] [Related]

  • 7. Role of haem oxygenase in the renoprotective effects of soluble epoxide hydrolase inhibition in diabetic spontaneously hypertensive rats.
    Elmarakby AA, Faulkner J, Pye C, Rouch K, Alhashim A, Maddipati KR, Baban B.
    Clin Sci (Lond); 2013 Oct 01; 125(7):349-59. PubMed ID: 23611540
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  • 9. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats.
    Koeners MP, Wesseling S, Ulu A, Sepúlveda RL, Morisseau C, Braam B, Hammock BD, Joles JA.
    Am J Physiol Endocrinol Metab; 2011 Apr 01; 300(4):E691-8. PubMed ID: 21266668
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  • 11. Early postnatal treatment with soluble epoxide hydrolase inhibitor or 15-deoxy-Δ(12,14)-prostagandin J2 prevents prenatal dexamethasone and postnatal high saturated fat diet induced programmed hypertension in adult rat offspring.
    Lu PC, Sheen JM, Yu HR, Lin YJ, Chen CC, Tiao MM, Tsai CC, Huang LT, Tain YL.
    Prostaglandins Other Lipid Mediat; 2016 Jul 01; 124():1-8. PubMed ID: 27210044
    [Abstract] [Full Text] [Related]

  • 12. Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.
    Simpkins AN, Rudic RD, Schreihofer DA, Roy S, Manhiani M, Tsai HJ, Hammock BD, Imig JD.
    Am J Pathol; 2009 Jun 01; 174(6):2086-95. PubMed ID: 19435785
    [Abstract] [Full Text] [Related]

  • 13. Soluble Epoxide Hydrolase Inhibition Attenuates Proteinuria by Alleviating Renal Inflammation and Podocyte Injuries in Adriamycin-Induced Nephropathy.
    Niu Q, Guo Z, Liang Y, Zuo L.
    Int J Mol Sci; 2024 Oct 02; 25(19):. PubMed ID: 39408958
    [Abstract] [Full Text] [Related]

  • 14. Soluble epoxide hydrolase inhibition ameliorates proteinuria-induced epithelial-mesenchymal transition by regulating the PI3K-Akt-GSK-3β signaling pathway.
    Liang Y, Jing Z, Deng H, Li Z, Zhuang Z, Wang S, Wang Y.
    Biochem Biophys Res Commun; 2024 Oct 02; 463(1-2):70-5. PubMed ID: 25986738
    [Abstract] [Full Text] [Related]

  • 15. Soluble Epoxide Hydrolase Inhibitor Ameliorates Olfactory Dysfunction, Modulates Microglia Polarization, and Attenuates Neuroinflammation after Ischemic Brain Injury.
    Yeh CF, Chuang TY, Lan MY, Lin YY, Huang WH, Hung YW.
    J Neuroimmune Pharmacol; 2024 Oct 17; 19(1):54. PubMed ID: 39417923
    [Abstract] [Full Text] [Related]

  • 16. Soluble epoxide hydrolase: a novel therapeutic target in stroke.
    Zhang W, Koerner IP, Noppens R, Grafe M, Tsai HJ, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ.
    J Cereb Blood Flow Metab; 2007 Dec 17; 27(12):1931-40. PubMed ID: 17440491
    [Abstract] [Full Text] [Related]

  • 17. 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.
    Anandan SK, Webb HK, Chen D, Wang YX, Aavula BR, Cases S, Cheng Y, Do ZN, Mehra U, Tran V, Vincelette J, Waszczuk J, White K, Wong KR, Zhang LN, Jones PD, Hammock BD, Patel DV, Whitcomb R, MacIntyre DE, Sabry J, Gless R.
    Bioorg Med Chem Lett; 2011 Feb 01; 21(3):983-8. PubMed ID: 21211973
    [Abstract] [Full Text] [Related]

  • 18. Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.
    Lee JP, Yang SH, Lee HY, Kim B, Cho JY, Paik JH, Oh YJ, Kim DK, Lim CS, Kim YS.
    PLoS One; 2012 Feb 01; 7(5):e37075. PubMed ID: 22590647
    [Abstract] [Full Text] [Related]

  • 19. Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion-induced cardiac damage in normal, hypertensive, and diabetic rats.
    Islam O, Patil P, Goswami SK, Razdan R, Inamdar MN, Rizwan M, Mathew J, Inceoglu B, Stephen Lee KS, Hwang SH, Hammock BD.
    Cardiovasc Ther; 2017 Jun 01; 35(3):. PubMed ID: 28296232
    [Abstract] [Full Text] [Related]

  • 20. Soluble epoxide hydrolase inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways.
    Dong XW, Jia YL, Ge LT, Jiang B, Jiang JX, Shen J, Jin YC, Guan Y, Sun Y, Xie QM.
    Toxicology; 2017 Aug 15; 389():31-41. PubMed ID: 28694203
    [Abstract] [Full Text] [Related]

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