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186 related items for PubMed ID: 18460448

  • 1. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through activation of c-jun N-terminal kinase.
    Lei P, Abdelrahim M, Cho SD, Liu S, Chintharlapalli S, Safe S.
    Carcinogenesis; 2008 Jun; 29(6):1139-47. PubMed ID: 18460448
    [Abstract] [Full Text] [Related]

  • 2. Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes.
    Lei P, Abdelrahim M, Cho SD, Liu X, Safe S.
    Mol Cancer Ther; 2008 Oct; 7(10):3363-72. PubMed ID: 18852139
    [Abstract] [Full Text] [Related]

  • 3. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit ovarian cancer cell growth through peroxisome proliferator-activated receptor-dependent and independent pathways.
    Lei P, Abdelrahim M, Safe S.
    Mol Cancer Ther; 2006 Sep; 5(9):2324-36. PubMed ID: 16985067
    [Abstract] [Full Text] [Related]

  • 4. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit proliferation of estrogen receptor-negative breast cancer cells by activation of multiple pathways.
    Vanderlaag K, Su Y, Frankel AE, Grage H, Smith R, Khan S, Safe S.
    Breast Cancer Res Treat; 2008 May; 109(2):273-83. PubMed ID: 17624585
    [Abstract] [Full Text] [Related]

  • 5. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways.
    Chintharlapalli S, Papineni S, Safe S.
    Mol Cancer Ther; 2006 May; 5(5):1362-70. PubMed ID: 16731770
    [Abstract] [Full Text] [Related]

  • 6. 1,1-bis(3'-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells.
    Cho SD, Lei P, Abdelrahim M, Yoon K, Liu S, Guo J, Papineni S, Chintharlapalli S, Safe S.
    Mol Carcinog; 2008 Apr; 47(4):252-63. PubMed ID: 17957723
    [Abstract] [Full Text] [Related]

  • 7. Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells.
    Guo J, Chintharlapalli S, Lee SO, Cho SD, Lei P, Papineni S, Safe S.
    Cancer Chemother Pharmacol; 2010 May; 66(1):141-50. PubMed ID: 19823826
    [Abstract] [Full Text] [Related]

  • 8. 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce apoptosis and inhibit renal cell carcinoma growth.
    York M, Abdelrahim M, Chintharlapalli S, Lucero SD, Safe S.
    Clin Cancer Res; 2007 Nov 15; 13(22 Pt 1):6743-52. PubMed ID: 18006776
    [Abstract] [Full Text] [Related]

  • 9. 3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.
    Abdelrahim M, Newman K, Vanderlaag K, Samudio I, Safe S.
    Carcinogenesis; 2006 Apr 15; 27(4):717-28. PubMed ID: 16332727
    [Abstract] [Full Text] [Related]

  • 10. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
    Vanderlaag K, Su Y, Frankel AE, Burghardt RC, Barhoumi R, Chadalapaka G, Jutooru I, Safe S.
    BMC Cancer; 2010 Dec 03; 10():669. PubMed ID: 21129193
    [Abstract] [Full Text] [Related]

  • 11. Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways.
    Cho SD, Yoon K, Chintharlapalli S, Abdelrahim M, Lei P, Hamilton S, Khan S, Ramaiah SK, Safe S.
    Cancer Res; 2007 Jan 15; 67(2):674-83. PubMed ID: 17234778
    [Abstract] [Full Text] [Related]

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  • 13. PPARγ-inactive Δ2-troglitazone independently triggers ER stress and apoptosis in breast cancer cells.
    Colin-Cassin C, Yao X, Cerella C, Chbicheb S, Kuntz S, Mazerbourg S, Boisbrun M, Chapleur Y, Diederich M, Flament S, Grillier-Vuissoz I.
    Mol Carcinog; 2015 May 15; 54(5):393-404. PubMed ID: 24293218
    [Abstract] [Full Text] [Related]

  • 14. Tocotrienols induce apoptosis in breast cancer cell lines via an endoplasmic reticulum stress-dependent increase in extrinsic death receptor signaling.
    Park SK, Sanders BG, Kline K.
    Breast Cancer Res Treat; 2010 Nov 15; 124(2):361-75. PubMed ID: 20157774
    [Abstract] [Full Text] [Related]

  • 15. Chemopreventive effects of synthetic C-substituted diindolylmethanes originating from cruciferous vegetables in human oral cancer cells.
    Shin JA, Shim JH, Choi ES, Leem DH, Kwon KH, Lee SO, Safe S, Cho NP, Cho SD.
    Eur J Cancer Prev; 2011 Sep 15; 20(5):417-25. PubMed ID: 21597379
    [Abstract] [Full Text] [Related]

  • 16. 1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes are peroxisome proliferator-activated receptor gamma agonists but decrease HCT-116 colon cancer cell survival through receptor-independent activation of early growth response-1 and nonsteroidal anti-inflammatory drug-activated gene-1.
    Chintharlapalli S, Papineni S, Baek SJ, Liu S, Safe S.
    Mol Pharmacol; 2005 Dec 15; 68(6):1782-92. PubMed ID: 16155208
    [Abstract] [Full Text] [Related]

  • 17. Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs.
    Safe S, Papineni S, Chintharlapalli S.
    Cancer Lett; 2008 Oct 08; 269(2):326-38. PubMed ID: 18501502
    [Abstract] [Full Text] [Related]

  • 18. A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.
    Qin C, Morrow D, Stewart J, Spencer K, Porter W, Smith R, Phillips T, Abdelrahim M, Samudio I, Safe S.
    Mol Cancer Ther; 2004 Mar 08; 3(3):247-60. PubMed ID: 15026545
    [Abstract] [Full Text] [Related]

  • 19. 1,1-bis(3'-indolyl)-1-(p-substituted phenyl)methanes decrease mitochondrial membrane potential and induce apoptosis in endometrial and other cancer cell lines.
    Hong J, Samudio I, Chintharlapalli S, Safe S.
    Mol Carcinog; 2008 Jul 08; 47(7):492-507. PubMed ID: 18085536
    [Abstract] [Full Text] [Related]

  • 20. Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.
    Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S.
    J Biol Chem; 2005 Jul 01; 280(26):24903-14. PubMed ID: 15871945
    [Abstract] [Full Text] [Related]

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