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215 related items for PubMed ID: 18472958

  • 1. Integrin alpha 6 beta 4 promotes migration, invasion through Tiam1 upregulation, and subsequent Rac activation.
    Cruz-Monserrate Z, O'Connor KL.
    Neoplasia; 2008 May; 10(5):408-17. PubMed ID: 18472958
    [Abstract] [Full Text] [Related]

  • 2. PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1.
    Mula RV, Bhatia V, Falzon M.
    Cancer Lett; 2010 Dec 01; 298(1):119-27. PubMed ID: 20637541
    [Abstract] [Full Text] [Related]

  • 3. Integrin α6β4 Promotes Autocrine Epidermal Growth Factor Receptor (EGFR) Signaling to Stimulate Migration and Invasion toward Hepatocyte Growth Factor (HGF).
    Carpenter BL, Chen M, Knifley T, Davis KA, Harrison SMW, Stewart RL, O'Connor KL.
    J Biol Chem; 2015 Nov 06; 290(45):27228-27238. PubMed ID: 26381405
    [Abstract] [Full Text] [Related]

  • 4. Balanced Tiam1-rac1 and RhoA drives proliferation and invasion of pancreatic cancer cells.
    Guo X, Wang M, Jiang J, Xie C, Peng F, Li X, Tian R, Qin R.
    Mol Cancer Res; 2013 Mar 06; 11(3):230-9. PubMed ID: 23322732
    [Abstract] [Full Text] [Related]

  • 5. Integrin α6β4 cooperates with LPA signaling to stimulate Rac through AKAP-Lbc-mediated RhoA activation.
    O'Connor KL, Chen M, Towers LN.
    Am J Physiol Cell Physiol; 2012 Feb 01; 302(3):C605-14. PubMed ID: 22049212
    [Abstract] [Full Text] [Related]

  • 6. Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration.
    Wang S, Watanabe T, Matsuzawa K, Katsumi A, Kakeno M, Matsui T, Ye F, Sato K, Murase K, Sugiyama I, Kimura K, Mizoguchi A, Ginsberg MH, Collard JG, Kaibuchi K.
    J Cell Biol; 2012 Oct 15; 199(2):331-45. PubMed ID: 23071154
    [Abstract] [Full Text] [Related]

  • 7. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar 15; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 8. Regulation of breast cancer cell motility by T-cell lymphoma invasion and metastasis-inducing protein.
    Adams HC, Chen R, Liu Z, Whitehead IP.
    Breast Cancer Res; 2010 Mar 15; 12(5):R69. PubMed ID: 20819206
    [Abstract] [Full Text] [Related]

  • 9. The Rac activator Tiam1 is required for (alpha)3(beta)1-mediated laminin-5 deposition, cell spreading, and cell migration.
    Hamelers IH, Olivo C, Mertens AE, Pegtel DM, van der Kammen RA, Sonnenberg A, Collard JG.
    J Cell Biol; 2005 Dec 05; 171(5):871-81. PubMed ID: 16330714
    [Abstract] [Full Text] [Related]

  • 10. 5-Lipoxygenase and cysteinyl leukotriene receptor 1 regulate epidermal growth factor-induced cell migration through Tiam1 upregulation and Rac1 activation.
    Magi S, Takemoto Y, Kobayashi H, Kasamatsu M, Akita T, Tanaka A, Takano K, Tashiro E, Igarashi Y, Imoto M.
    Cancer Sci; 2014 Mar 05; 105(3):290-6. PubMed ID: 24350867
    [Abstract] [Full Text] [Related]

  • 11. Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion.
    Díaz J, Mendoza P, Ortiz R, Díaz N, Leyton L, Stupack D, Quest AF, Torres VA.
    J Cell Sci; 2014 Jun 01; 127(Pt 11):2401-6. PubMed ID: 24659799
    [Abstract] [Full Text] [Related]

  • 12. The sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migration.
    Saxena M, Dykes SS, Malyarchuk S, Wang AE, Cardelli JA, Pruitt K.
    Oncogene; 2015 Jan 08; 34(2):188-98. PubMed ID: 24362520
    [Abstract] [Full Text] [Related]

  • 13. Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration.
    Bourguignon LY, Zhu H, Shao L, Chen YW.
    J Cell Biol; 2000 Jul 10; 150(1):177-91. PubMed ID: 10893266
    [Abstract] [Full Text] [Related]

  • 14. CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
    Singleton PA, Salgia R, Moreno-Vinasco L, Moitra J, Sammani S, Mirzapoiazova T, Garcia JG.
    J Biol Chem; 2007 Oct 19; 282(42):30643-57. PubMed ID: 17702746
    [Abstract] [Full Text] [Related]

  • 15. Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells.
    Minard ME, Ellis LM, Gallick GE.
    Clin Exp Metastasis; 2006 Oct 19; 23(5-6):301-13. PubMed ID: 17086355
    [Abstract] [Full Text] [Related]

  • 16. Tiam1 is recruited to β1-integrin complexes by 14-3-3ζ where it mediates integrin-induced Rac1 activation and motility.
    O'Toole TE, Bialkowska K, Li X, Fox JE.
    J Cell Physiol; 2011 Nov 19; 226(11):2965-78. PubMed ID: 21302295
    [Abstract] [Full Text] [Related]

  • 17. Rac affects invasion of human renal cell carcinomas by up-regulating tissue inhibitor of metalloproteinases (TIMP)-1 and TIMP-2 expression.
    Engers R, Springer E, Michiels F, Collard JG, Gabbert HE.
    J Biol Chem; 2001 Nov 09; 276(45):41889-97. PubMed ID: 11551917
    [Abstract] [Full Text] [Related]

  • 18. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.
    J Cell Biol; 1997 Nov 03; 139(3):797-807. PubMed ID: 9348295
    [Abstract] [Full Text] [Related]

  • 19. RAC1 GTP-ase signals Wnt-beta-catenin pathway mediated integrin-directed metastasis-associated tumor cell phenotypes in triple negative breast cancers.
    De P, Carlson JH, Jepperson T, Willis S, Leyland-Jones B, Dey N.
    Oncotarget; 2017 Jan 10; 8(2):3072-3103. PubMed ID: 27902969
    [Abstract] [Full Text] [Related]

  • 20. HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway.
    Birukova AA, Alekseeva E, Mikaelyan A, Birukov KG.
    FASEB J; 2007 Sep 10; 21(11):2776-86. PubMed ID: 17428964
    [Abstract] [Full Text] [Related]

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