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Journal Abstract Search

315 related items for PubMed ID: 18477509

  • 21. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

  • 22. Synthesis and evaluation of 4/5-hydroxy-2,3-diaryl(substituted)-cyclopent-2-en-1-ones as cis-restricted analogues of combretastatin A-4 as novel anticancer agents.
    Gurjar MK, Wakharkar RD, Singh AT, Jaggi M, Borate HB, Shinde PD, Verma R, Rajendran P, Dutt S, Singh G, Sanna VK, Singh MK, Srivastava SK, Mahajan VA, Jadhav VH, Dutta K, Krishnan K, Chaudhary A, Agarwal SK, Mukherjee R, Burman AC.
    J Med Chem; 2007 Apr 19; 50(8):1744-53. PubMed ID: 17373779
    [Abstract] [Full Text] [Related]

  • 23. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2006 Dec 28; 49(26):7816-25. PubMed ID: 17181164
    [Abstract] [Full Text] [Related]

  • 24. Synthesis and cytotoxic evaluation of N-(4-methoxy-1H-benzo[d]imidazol-7-yl)-arylsulfonamide and N-aryl-(4-methoxy-1H-benzo[d]imidazol)-7-sulfonamide analogs of combretastatin A-4.
    Zhou J, Zhang Y, Cui YW, Li ZM, Song HR, Dong JH, Chen XG, Xu BL.
    J Asian Nat Prod Res; 2011 Apr 28; 13(4):330-40. PubMed ID: 21462036
    [Abstract] [Full Text] [Related]

  • 25. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
    Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):1113-21. PubMed ID: 22189271
    [Abstract] [Full Text] [Related]

  • 26. Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs.
    Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Lenoir C, Desravines D, Dubois J, Brion JD, Alami M.
    Eur J Med Chem; 2013 Apr 15; 62():28-39. PubMed ID: 23353744
    [Abstract] [Full Text] [Related]

  • 27. 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Schmidt P, Böhm KJ, Baasner S, Müller K, Unger E, Gerlach M, Günther EG.
    J Med Chem; 2009 Mar 12; 52(5):1284-94. PubMed ID: 19220018
    [Abstract] [Full Text] [Related]

  • 28. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
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  • 29. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
    Barnes NG, Parker AW, Ahmed Mal Ullah AA, Ragazzon PA, Hadfield JA.
    Bioorg Med Chem; 2020 Oct 01; 28(19):115684. PubMed ID: 32912434
    [Abstract] [Full Text] [Related]

  • 30. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M, Kajita D, Matsumoto Y, Hashimoto Y.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7381-91. PubMed ID: 24139940
    [Abstract] [Full Text] [Related]

  • 31. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Zuse A, Schmidt P, Baasner S, Böhm KJ, Müller K, Gerlach M, Günther EG, Unger E, Prinz H.
    J Med Chem; 2007 Nov 29; 50(24):6059-66. PubMed ID: 17973361
    [Abstract] [Full Text] [Related]

  • 32. Synthesis and biological evaluation of 2-(3',4',5'-trimethoxybenzoyl)-3-amino 5-aryl thiophenes as a new class of tubulin inhibitors.
    Romagnoli R, Baraldi PG, Remusat V, Carrion MD, Cara CL, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Balzarini J, Jordan MA, Hamel E.
    J Med Chem; 2006 Oct 19; 49(21):6425-8. PubMed ID: 17034150
    [Abstract] [Full Text] [Related]

  • 33. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR, Rhodes MR, Herald DL, Hamel E, Schmidt JM, Pettit RK.
    J Med Chem; 2005 Jun 16; 48(12):4087-99. PubMed ID: 15943482
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  • 34. Synthesis and anti-proliferative in-vitro activity of two natural dihydrostilbenes and their analogues.
    Zhang WG, Zhao R, Ren J, Ren LX, Lin JG, Liu DL, Wu YL, Yao XS.
    Arch Pharm (Weinheim); 2007 May 16; 340(5):244-50. PubMed ID: 17516577
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  • 35. Synthesis and biological evaluation of 3,4-diaryl-5-aminoisoxazole derivatives.
    Liu T, Dong X, Xue N, Wu R, He Q, Yang B, Hu Y.
    Bioorg Med Chem; 2009 Sep 01; 17(17):6279-85. PubMed ID: 19665898
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  • 36. 4,5-Diaryl-3-aminopyrazole derivatives as analogs of Combretastatin A-4: synthesis and biological evaluation.
    Liu T, Cui R, Chen J, Zhang J, He Q, Yang B, Hu Y.
    Arch Pharm (Weinheim); 2011 May 01; 344(5):279-86. PubMed ID: 21290430
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  • 37. Synthesis and biological evaluation of 4-arylcoumarin analogues of combretastatins.
    Bailly C, Bal C, Barbier P, Combes S, Finet JP, Hildebrand MP, Peyrot V, Wattez N.
    J Med Chem; 2003 Dec 04; 46(25):5437-44. PubMed ID: 14640552
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  • 38. New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
    De Martino G, Edler MC, La Regina G, Coluccia A, Barbera MC, Barrow D, Nicholson RI, Chiosis G, Brancale A, Hamel E, Artico M, Silvestri R.
    J Med Chem; 2006 Feb 09; 49(3):947-54. PubMed ID: 16451061
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  • 39. Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.
    Xie F, Zhao H, Li D, Chen H, Quan H, Shi X, Lou L, Hu Y.
    J Med Chem; 2011 May 12; 54(9):3200-5. PubMed ID: 21480626
    [Abstract] [Full Text] [Related]

  • 40. 3-(3,4,5-Trimethoxyphenylselenyl)-1H-indoles and their selenoxides as combretastatin A-4 analogs: microwave-assisted synthesis and biological evaluation.
    Wen Z, Xu J, Wang Z, Qi H, Xu Q, Bai Z, Zhang Q, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2015 Jan 27; 90():184-94. PubMed ID: 25461319
    [Abstract] [Full Text] [Related]

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