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Journal Abstract Search

57 related items for PubMed ID: 1847758

  • 21. Pharmacokinetics and pharmacodynamics of single and multiple oral doses of a novel 5-lipoxygenase inhibitor (ABT-761) in healthy volunteers.
    Wong SL, Drajesk J, Chang M, Lanni C, Witt G, Hansen R, Awni WM.
    Clin Pharmacol Ther; 1998 Mar; 63(3):324-31. PubMed ID: 9542476
    [Abstract] [Full Text] [Related]

  • 22. Dioxabicyclooctanyl naphthalenenitriles as nonredox 5-lipoxygenase inhibitors: structure-activity relationship study directed toward the improvement of metabolic stability.
    Delorme D, Ducharme Y, Brideau C, Chan CC, Chauret N, Desmarais S, Dubé D, Falgueyret JP, Fortin R, Guay J, Hamel P, Jones TR, Lépine C, Li C, McAuliffe M, McFarlane CS, Nicoll-Griffith DA, Riendeau D, Yergey JA, Girard Y.
    J Med Chem; 1996 Sep 27; 39(20):3951-70. PubMed ID: 8831761
    [Abstract] [Full Text] [Related]

  • 23. [Role of exogenous arachidonate in the biosynthesis of 5-lipoxygenase metabolites of arachidonic acid by human polymorphonuclear leukocytes induced by the calcium ionophore A23187].
    Sud'ina GF, Barskiĭ OA, Varfolomeev SD.
    Biokhimiia; 1990 Sep 27; 55(9):1655-9. PubMed ID: 2127729
    [Abstract] [Full Text] [Related]

  • 24. The properties of A-69412: a small hydrophilic 5-lipoxygenase inhibitor.
    Bell RL, Bouska J, Young PR, Lanni C, Machinist J, Malo PE, Summers JB, Brooks DW, Carter GW.
    Agents Actions; 1993 Mar 27; 38(3-4):178-87. PubMed ID: 8213344
    [Abstract] [Full Text] [Related]

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  • 27. Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis.
    Summers JB, Gunn BP, Martin JG, Martin MB, Mazdiyasni H, Stewart AO, Young PR, Bouska JB, Goetze AM, Dyer RD.
    J Med Chem; 1988 Oct 27; 31(10):1960-4. PubMed ID: 3172130
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  • 29. Properties of LTA4 synthase in human neutrophil preparations.
    Hill E, MacMillan D, Sala A, Henson PM, Murphy RC.
    Adv Prostaglandin Thromboxane Leukot Res; 1995 Oct 27; 23():155-7. PubMed ID: 7732823
    [No Abstract] [Full Text] [Related]

  • 30. Effect of 5-lipoxygenase inhibitor on canine pancreatic allotransplantation.
    Horichi H, Izumi R, Shimizu K, Konishi K, Kitabayashi K, Watanabe T, Miyazaki I.
    Transplant Proc; 1991 Feb 27; 23(1 Pt 2):1679-80. PubMed ID: 1846481
    [No Abstract] [Full Text] [Related]

  • 31. The 5-lipoxygenase inhibitor BWA4C impairs osteoclastic resorption in a synchronized model of bone remodeling.
    Franchi-Miller C, Saffar JL.
    Bone; 1995 Aug 27; 17(2):185-91. PubMed ID: 8554928
    [Abstract] [Full Text] [Related]

  • 32. Pseudoperoxidase activity of 5-lipoxygenase stimulated by potent benzofuranol and N-hydroxyurea inhibitors of the lipoxygenase reaction.
    Riendeau D, Falgueyret JP, Guay J, Ueda N, Yamamoto S.
    Biochem J; 1991 Feb 15; 274 ( Pt 1)(Pt 1):287-92. PubMed ID: 2001245
    [Abstract] [Full Text] [Related]

  • 33. The effects of a 5-lipoxygenase inhibitor, BW A4C, on the acute response to inhaled PAF in man.
    Spencer DA, Sampson AP, Evans JM, Garland LG, Piper PJ, Costello JF.
    Ann N Y Acad Sci; 1991 Feb 15; 629():430-1. PubMed ID: 1952568
    [No Abstract] [Full Text] [Related]

  • 34. Orally active hydroxamic acid inhibitors of leukotriene biosynthesis.
    Summers JB, Gunn BP, Martin JG, Mazdiyasni H, Stewart AO, Young PR, Goetze AM, Bouska JB, Dyer RD, Brooks DW.
    J Med Chem; 1988 Jan 15; 31(1):3-5. PubMed ID: 3336029
    [No Abstract] [Full Text] [Related]

  • 35. Inhibition of leucotriene-synthesis improves dorsal skin flap survival in the rat.
    Törkvist L, Adén U, Lundeberg T, Raud J.
    Acta Physiol Scand; 1995 Aug 15; 154(4):511-2. PubMed ID: 7484177
    [No Abstract] [Full Text] [Related]

  • 36. Acetohydroxamic acids as potent, selective, orally active 5-lipoxygenase inhibitors.
    Jackson WP, Islip PJ, Kneen G, Pugh A, Wates PJ.
    J Med Chem; 1988 Mar 15; 31(3):499-500. PubMed ID: 3346867
    [No Abstract] [Full Text] [Related]

  • 37. Effects of certain hydroxamic acids on virus replication.
    Gale GR, Smith AB.
    Experientia; 1968 Feb 15; 24(2):194-5. PubMed ID: 4868479
    [No Abstract] [Full Text] [Related]

  • 38. Effect of hydroxyurea analogues in regenerating rat liver.
    Hill RB, Gordon JA.
    Exp Mol Pathol; 1968 Aug 15; 9(1):71-6. PubMed ID: 5667368
    [No Abstract] [Full Text] [Related]

  • 39. Quantitative structure-activity relationship study on some 5-lipoxygenase inhibitors.
    Gupta SP, Gupta JK.
    J Enzyme Inhib; 1990 Aug 15; 3(3):179-88. PubMed ID: 2079634
    [Abstract] [Full Text] [Related]

  • 40. Novel hydroxamates and myocardial reperfusion injury.
    Collis CS, Davies MJ, Rice-Evans C.
    Biochem Soc Trans; 1993 May 15; 21(2):96S. PubMed ID: 8359549
    [No Abstract] [Full Text] [Related]

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