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86 related items for PubMed ID: 1847818

  • 1. The diacylglycerol kinase inhibitor, R59949, potentiates secretion but not increased phosphorylation of a 47 kDalton protein in human platelets.
    Rodríguez-Liñares B, Walker T, Watson S.
    Biochem Pharmacol; 1991 Mar 01; 41(5):835-8. PubMed ID: 1847818
    [Abstract] [Full Text] [Related]

  • 2. A diacylglycerol kinase inhibitor, R59022, potentiates secretion by and aggregation of thrombin-stimulated human platelets.
    Nunn DL, Watson SP.
    Biochem J; 1987 May 01; 243(3):809-13. PubMed ID: 2821994
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of thrombin-induced Ca²⁺ influx in platelets by R59949, an inhibitor of diacylglycerol kinase.
    Marumo M, Nakano T, Takeda Y, Goto K, Wakabayashi I.
    J Pharm Pharmacol; 2012 Jun 01; 64(6):855-61. PubMed ID: 22571264
    [Abstract] [Full Text] [Related]

  • 4. The use of diacylglycerol kinase inhibitors for elucidating the roles of protein kinase C.
    de Chaffoy de Courcelles D.
    Adv Second Messenger Phosphoprotein Res; 1990 Jun 01; 24():491-6. PubMed ID: 2169824
    [No Abstract] [Full Text] [Related]

  • 5. Differential effects of the diacylglycerol kinase inhibitor R59022 on thrombin versus collagen-induced human platelet secretion.
    Joseph S, Krishnamurthi S, Kakkar VV.
    Biochim Biophys Acta; 1988 Apr 02; 969(1):9-17. PubMed ID: 2832002
    [Abstract] [Full Text] [Related]

  • 6. Activation of phospholipase C and protein kinase C has little involvement in ADP-induced primary aggregation of human platelets: effects of diacylglycerols, the diacylglycerols, the diacylglycerol kinase inhibitor R59022, staurosporine and okadaic acid.
    Packham MA, Livne AA, Ruben DH, Rand ML.
    Biochem J; 1993 Mar 15; 290 ( Pt 3)(Pt 3):849-56. PubMed ID: 8384448
    [Abstract] [Full Text] [Related]

  • 7. The role of endogenously formed diacylglycerol in the propagation and termination of platelet activation. A biochemical and functional analysis using the novel diacylglycerol kinase inhibitor, R 59 949.
    de Chaffoy de Courcelles D, Roevens P, Van Belle H, Kennis L, Somers Y, De Clerck F.
    J Biol Chem; 1989 Feb 25; 264(6):3274-85. PubMed ID: 2536741
    [Abstract] [Full Text] [Related]

  • 8. R 59 022, a diacylglycerol kinase inhibitor. Its effect on diacylglycerol and thrombin-induced C kinase activation in the intact platelet.
    de Chaffoy de Courcelles DC, Roevens P, Van Belle H.
    J Biol Chem; 1985 Dec 15; 260(29):15762-70. PubMed ID: 2999135
    [Abstract] [Full Text] [Related]

  • 9. The diacylglycerol kinase inhibitor, R59022, potentiates cholecystokinin-induced enzyme secretion from rabbit pancreatic acini.
    Ederveen AG, van Emst-de Vries SE, De Pont JJ, Willems PH.
    Eur J Biochem; 1990 Mar 10; 188(2):333-8. PubMed ID: 1690650
    [Abstract] [Full Text] [Related]

  • 10. A role of diacylglycerol kinase in stimulus-secretion coupling of human platelets. Dissociation of serotonin secretion from Ca2+ mobilization.
    Tohmatsu T, Nakashima S, Hattori H, Suganuma A, Nozawa Y.
    Thromb Res; 1987 Jul 01; 47(1):25-35. PubMed ID: 2821648
    [Abstract] [Full Text] [Related]

  • 11. Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes.
    Jiang Y, Sakane F, Kanoh H, Walsh JP.
    Biochem Pharmacol; 2000 Apr 01; 59(7):763-72. PubMed ID: 10718334
    [Abstract] [Full Text] [Related]

  • 12. The action of the protein kinase C inhibitor, staurosporine, on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin.
    Watson SP, McNally J, Shipman LJ, Godfrey PP.
    Biochem J; 1988 Jan 15; 249(2):345-50. PubMed ID: 3257691
    [Abstract] [Full Text] [Related]

  • 13. Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.
    Bursell SE, Takagi C, Clermont AC, Takagi H, Mori F, Ishii H, King GL.
    Invest Ophthalmol Vis Sci; 1997 Dec 15; 38(13):2711-20. PubMed ID: 9418723
    [Abstract] [Full Text] [Related]

  • 14. Fatty acids inhibit growth-factor-induced diacylglycerol kinase alpha activation in vascular smooth-muscle cells.
    Du X, Jiang Y, Qian W, Lu X, Walsh JP.
    Biochem J; 2001 Jul 01; 357(Pt 1):275-82. PubMed ID: 11415460
    [Abstract] [Full Text] [Related]

  • 15. Ethanol inhibits thrombin-induced secretion by human platelets at a site distinct from phospholipase C or protein kinase C.
    Benistant C, Rubin R.
    Biochem J; 1990 Jul 15; 269(2):489-97. PubMed ID: 2117442
    [Abstract] [Full Text] [Related]

  • 16. Prostacyclin inhibition of phosphatidic acid synthesis in human platelets is not mediated by protein kinase C.
    Lapetina EG.
    Biochem Biophys Res Commun; 1984 Apr 16; 120(1):37-44. PubMed ID: 6231930
    [Abstract] [Full Text] [Related]

  • 17. Effect of phorbol ester treatment on receptor-mediated versus G-protein-activator-mediated responses in platelets. Evidence for a two-site action of phorbol ester at the level of G-protein function.
    Krishnamurthi S, Wheeler-Jones CP, Kakkar VV.
    Biochem J; 1989 Aug 15; 262(1):77-81. PubMed ID: 2510716
    [Abstract] [Full Text] [Related]

  • 18. Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors.
    Bishop WR, August J, Petrin JM, Pai JK.
    Biochem J; 1990 Jul 15; 269(2):465-73. PubMed ID: 2386487
    [Abstract] [Full Text] [Related]

  • 19. Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid.
    Erickson RW, Langel-Peveri P, Traynor-Kaplan AE, Heyworth PG, Curnutte JT.
    J Biol Chem; 1999 Aug 06; 274(32):22243-50. PubMed ID: 10428791
    [Abstract] [Full Text] [Related]

  • 20. Noradrenaline release and the effect of endogenous activation of the phospholipase C/protein kinase C signalling pathway in rat atria.
    Majewski H, Kotsonis P, Murphy TV, Barrington M.
    Br J Pharmacol; 1997 Jul 06; 121(6):1196-202. PubMed ID: 9249257
    [Abstract] [Full Text] [Related]

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