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554 related items for PubMed ID: 18479250
1. A ternary complex of hydroxycinnamoyl-CoA hydratase-lyase (HCHL) with acetyl-CoA and vanillin gives insights into substrate specificity and mechanism. Bennett JP, Bertin L, Moulton B, Fairlamb IJ, Brzozowski AM, Walton NJ, Grogan G. Biochem J; 2008 Sep 01; 414(2):281-9. PubMed ID: 18479250 [Abstract] [Full Text] [Related]
2. The 1.8 A resolution structure of hydroxycinnamoyl-coenzyme A hydratase-lyase (HCHL) from Pseudomonas fluorescens, an enzyme that catalyses the transformation of feruloyl-coenzyme A to vanillin. Leonard PM, Brzozowski AM, Lebedev A, Marshall CM, Smith DJ, Verma CS, Walton NJ, Grogan G. Acta Crystallogr D Biol Crystallogr; 2006 Dec 01; 62(Pt 12):1494-501. PubMed ID: 17139085 [Abstract] [Full Text] [Related]
3. Purification, crystallization and preliminary X-ray crystallographic analysis of hydroxycinnamoyl-coenzyme A hydratase-lyase (HCHL), a crotonase homologue active in phenylpropanoid metabolism. Leonard PM, Marshall CM, Dodson EJ, Walton NJ, Grogan G. Acta Crystallogr D Biol Crystallogr; 2004 Dec 01; 60(Pt 12 Pt 2):2343-5. PubMed ID: 15583385 [Abstract] [Full Text] [Related]
4. 4-hydroxycinnamoyl-CoA hydratase/lyase (HCHL)--An enzyme of phenylpropanoid chain cleavage from Pseudomonas. Mitra A, Kitamura Y, Gasson MJ, Narbad A, Parr AJ, Payne J, Rhodes MJ, Sewter C, Walton NJ. Arch Biochem Biophys; 1999 May 01; 365(1):10-6. PubMed ID: 10222033 [Abstract] [Full Text] [Related]
5. Mutational analysis of microbial hydroxycinnamoyl-CoA hydratase-lyase (HCHL) towards enhancement of binding affinity: A computational approach. Kumar P, Ghosh Sachan S, Poddar R. J Mol Graph Model; 2017 Oct 01; 77():94-105. PubMed ID: 28850897 [Abstract] [Full Text] [Related]
6. Rerouting the plant phenylpropanoid pathway by expression of a novel bacterial enoyl-CoA hydratase/lyase enzyme function. Mayer MJ, Narbad A, Parr AJ, Parker ML, Walton NJ, Mellon FA, Michael AJ. Plant Cell; 2001 Jul 01; 13(7):1669-82. PubMed ID: 11449058 [Abstract] [Full Text] [Related]
7. The crystal structure of enoyl-CoA hydratase complexed with octanoyl-CoA reveals the structural adaptations required for binding of a long chain fatty acid-CoA molecule. Engel CK, Kiema TR, Hiltunen JK, Wierenga RK. J Mol Biol; 1998 Feb 06; 275(5):847-59. PubMed ID: 9480773 [Abstract] [Full Text] [Related]
8. 4-Hydroxycinnamoyl-CoA hydratase/lyase, an enzyme of phenylpropanoid cleavage from Pseudomonas, causes formation of C(6)-C(1) acid and alcohol glucose conjugates when expressed in hairy roots of Datura stramonium L. Mitra A, Mayer MJ, Mellon FA, Michael AJ, Narbad A, Parr AJ, Waldron KW, Walton NJ. Planta; 2002 May 06; 215(1):79-89. PubMed ID: 12012244 [Abstract] [Full Text] [Related]
9. Role of glutamate 144 and glutamate 164 in the catalytic mechanism of enoyl-CoA hydratase. Hofstein HA, Feng Y, Anderson VE, Tonge PJ. Biochemistry; 1999 Jul 20; 38(29):9508-16. PubMed ID: 10413528 [Abstract] [Full Text] [Related]
10. Quantitative isotopic 13C nuclear magnetic resonance at natural abundance to probe enzyme reaction mechanisms via site-specific isotope fractionation: the case of the chain-shortening reaction for the bioconversion of ferulic acid to vanillin. Botosoa EP, Blumenstein C, MacKenzie DA, Silvestre V, Remaud GS, Kwiecień RA, Robins RJ. Anal Biochem; 2009 Oct 15; 393(2):182-8. PubMed ID: 19563771 [Abstract] [Full Text] [Related]
11. Evaluation of 3-hydroxy-3-methylglutaryl-coenzyme A lyase arginine-41 as a catalytic residue: use of acetyldithio-coenzyme A to monitor product enolization. Tuinstra RL, Wang CZ, Mitchell GA, Miziorko HM. Biochemistry; 2004 May 11; 43(18):5287-95. PubMed ID: 15122894 [Abstract] [Full Text] [Related]
12. Metabolism of ferulic acid to vanillin. A bacterial gene of the enoyl-SCoA hydratase/isomerase superfamily encodes an enzyme for the hydration and cleavage of a hydroxycinnamic acid SCoA thioester. Gasson MJ, Kitamura Y, McLauchlan WR, Narbad A, Parr AJ, Parsons EL, Payne J, Rhodes MJ, Walton NJ. J Biol Chem; 1998 Feb 13; 273(7):4163-70. PubMed ID: 9461612 [Abstract] [Full Text] [Related]
13. Interchange of catalytic activity within the 2-enoyl-coenzyme A hydratase/isomerase superfamily based on a common active site template. Xiang H, Luo L, Taylor KL, Dunaway-Mariano D. Biochemistry; 1999 Jun 15; 38(24):7638-52. PubMed ID: 10387003 [Abstract] [Full Text] [Related]
14. Crystal structure of 2-enoyl-CoA hydratase 2 from human peroxisomal multifunctional enzyme type 2. Koski KM, Haapalainen AM, Hiltunen JK, Glumoff T. J Mol Biol; 2005 Feb 04; 345(5):1157-69. PubMed ID: 15644212 [Abstract] [Full Text] [Related]
15. Glutamate-119 of the large alpha-subunit is the catalytic base in the hydration of 2-trans-enoyl-coenzyme A catalyzed by the multienzyme complex of fatty acid oxidation from Escherichia coli. He XY, Yang SY. Biochemistry; 1997 Sep 09; 36(36):11044-9. PubMed ID: 9283097 [Abstract] [Full Text] [Related]
16. Catalytic mechanism of scytalone dehydratase: site-directed mutagenisis, kinetic isotope effects, and alternate substrates. Basarab GS, Steffens JJ, Wawrzak Z, Schwartz RS, Lundqvist T, Jordan DB. Biochemistry; 1999 May 11; 38(19):6012-24. PubMed ID: 10320327 [Abstract] [Full Text] [Related]
17. Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction. Kurz LC, Nakra T, Stein R, Plungkhen W, Riley M, Hsu F, Drysdale GR. Biochemistry; 1998 Jul 07; 37(27):9724-37. PubMed ID: 9657685 [Abstract] [Full Text] [Related]
18. Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity. Lee HJ, Wang M, Paschke R, Nandy A, Ghisla S, Kim JJ. Biochemistry; 1996 Sep 24; 35(38):12412-20. PubMed ID: 8823176 [Abstract] [Full Text] [Related]
19. Thermodynamics of ligand binding and catalysis in human liver medium-chain acyl-CoA dehydrogenase: comparative studies involving normal and 3'-dephosphorylated C8-CoAs and wild-type and Asn191 --> Ala (N191A) mutant enzymes. Peterson KL, Peterson KM, Srivastava DK. Biochemistry; 1998 Sep 08; 37(36):12659-71. PubMed ID: 9730839 [Abstract] [Full Text] [Related]
20. Steroid recognition by chloramphenicol acetyltransferase: engineering and structural analysis of a high affinity fusidic acid binding site. Murray IA, Cann PA, Day PJ, Derrick JP, Sutcliffe MJ, Shaw WV, Leslie AG. J Mol Biol; 1995 Dec 15; 254(5):993-1005. PubMed ID: 7500366 [Abstract] [Full Text] [Related] Page: [Next] [New Search]