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Journal Abstract Search

157 related items for PubMed ID: 18479920

  • 21. Synthesis of Tic-D-Phe Psi[CH2-CH2] isostere and its use in the development of melanocortin receptor agonists.
    Tian X, Chen X, Gan L, Hayes JC, Switzer AG, Solinsky MG, Ebetino FH, Wos JA, Pinney BB, Farmer JA, Crossdoersen D, Sheldon RJ.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1721-5. PubMed ID: 16376076
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  • 22. Structure-activity relationships of piperazinebenzylamines as potent and selective agonists of the human melanocortin-4 receptor.
    Pontillo J, Tran JA, Arellano M, Fleck BA, Huntley R, Marinkovic D, Lanier M, Nelson J, Parker J, Saunders J, Tucci FC, Jiang W, Chen CW, White NS, Foster AC, Chen C.
    Bioorg Med Chem Lett; 2004 Sep 06; 14(17):4417-23. PubMed ID: 15357964
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  • 26. Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.
    Tian X, Field TB, Switzer AG, Mazur AW, Ebetino FH, Wos JA, Berberich SM, Jayasinghe LR, Obringer CM, Dowty ME, Pinney BB, Farmer JA, Crossdoersen D, Sheldon RJ.
    J Med Chem; 2006 Jul 27; 49(15):4745-61. PubMed ID: 16854081
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  • 31. Synthesis and biological activity of novel peptide mimetics as melanocortin receptor agonists.
    Liu XW, Ma J, Colson AO, Doersen DC, Ebetino FH.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):1223-8. PubMed ID: 18078748
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  • 34. Design and syntheses of melanocortin subtype-4 receptor agonists: evolution of the pyridazinone archetype.
    Ujjainwalla F, Warner D, Walsh TF, Wyvratt MJ, Zhou C, Yang L, Kalyani RN, MacNeil T, Van der Ploeg LH, Rosenblum CI, Tang R, Vongs A, Weinberg DH, Goulet MT.
    Bioorg Med Chem Lett; 2003 Dec 15; 13(24):4431-5. PubMed ID: 14643340
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  • 35. Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist.
    Palucki BL, Park MK, Nargund RP, Ye Z, Sebhat IK, Pollard PG, Kalyani RN, Tang R, Macneil T, Weinberg DH, Vongs A, Rosenblum CI, Doss GA, Miller RR, Stearns RA, Peng Q, Tamvakopoulos C, McGowan E, Martin WJ, Metzger JM, Shepherd CA, Strack AM, Macintyre DE, Van der Ploeg LH, Patchett AA.
    Bioorg Med Chem Lett; 2005 Jan 03; 15(1):171-5. PubMed ID: 15582434
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  • 39. Structure-activity relationship of a series of cyclohexylpiperidines bearing an amide side chain as antagonists of the human melanocortin-4 receptor.
    Tran JA, Pontillo J, Arellano M, Fleck BA, Tucci FC, Marinkovic D, Chen CW, Saunders J, Foster AC, Chen C.
    Bioorg Med Chem Lett; 2005 Jul 15; 15(14):3434-8. PubMed ID: 15950470
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  • 40. Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action.
    Van Huis CA, Casimiro-Garcia A, Bigge CF, Cody WL, Dudley DA, Filipski KJ, Heemstra RJ, Kohrt JT, Leadley RJ, Narasimhan LS, McClanahan T, Mochalkin I, Pamment M, Peterson JT, Sahasrabudhe V, Schaum RP, Edmunds JJ.
    Bioorg Med Chem; 2009 Mar 15; 17(6):2501-11. PubMed ID: 19231206
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