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Journal Abstract Search

329 related items for PubMed ID: 1848634

  • 1. 5-lipoxygenase inhibitory activity of zileuton.
    Carter GW, Young PR, Albert DH, Bouska J, Dyer R, Bell RL, Summers JB, Brooks DW.
    J Pharmacol Exp Ther; 1991 Mar; 256(3):929-37. PubMed ID: 1848634
    [Abstract] [Full Text] [Related]

  • 2. Pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase.
    McMillan RM, Spruce KE, Crawley GC, Walker ER, Foster SJ.
    Br J Pharmacol; 1992 Dec; 107(4):1042-7. PubMed ID: 1334748
    [Abstract] [Full Text] [Related]

  • 3. Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.
    Argentieri DC, Ritchie DM, Ferro MP, Kirchner T, Wachter MP, Anderson DW, Rosenthale ME, Capetola RJ.
    J Pharmacol Exp Ther; 1994 Dec; 271(3):1399-408. PubMed ID: 7996452
    [Abstract] [Full Text] [Related]

  • 4. ER-34122, a novel dual 5-lipoxygenase/cyclooxygenase inhibitor with potent anti-inflammatory activity in an arachidonic acid-induced ear inflammation model.
    Horizoe T, Nagakura N, Chiba K, Shirota H, Shinoda M, Kobayashi N, Numata H, Okamoto Y, Kobayashi S.
    Inflamm Res; 1998 Oct; 47(10):375-83. PubMed ID: 9831321
    [Abstract] [Full Text] [Related]

  • 5. Optimization of the potency and duration of action of N-hydroxyurea 5-lipoxygenase inhibitors.
    Bell RL, Bouska JB, Malo PE, Lanni C, Harris RR, Otis ER, Stewart AO, Brooks DW, Carter GW.
    J Pharmacol Exp Ther; 1995 Feb; 272(2):724-31. PubMed ID: 7853186
    [Abstract] [Full Text] [Related]

  • 6. Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.
    Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB.
    Inflamm Res; 1997 May; 46(5):168-79. PubMed ID: 9197987
    [Abstract] [Full Text] [Related]

  • 7. WY-50,295 tromethamine, a novel, orally active 5-lipoxygenase inhibitor: biochemical characterization and antiallergic activity.
    Grimes D, Sturm RJ, Marinari LR, Carlson RP, Berkenkopf JW, Musser JH, Kreft AF, Weichman BM.
    Eur J Pharmacol; 1993 May 19; 236(2):217-28. PubMed ID: 8391458
    [Abstract] [Full Text] [Related]

  • 8. Anti-inflammatory activity of a potent, selective leukotriene A4 hydrolase inhibitor in comparison with the 5-lipoxygenase inhibitor zileuton.
    Rao NL, Dunford PJ, Xue X, Jiang X, Lundeen KA, Coles F, Riley JP, Williams KN, Grice CA, Edwards JP, Karlsson L, Fourie AM.
    J Pharmacol Exp Ther; 2007 Jun 19; 321(3):1154-60. PubMed ID: 17371808
    [Abstract] [Full Text] [Related]

  • 9. A-78773: a selective, potent 5-lipoxygenase inhibitor.
    Bell RL, Brooks DW, Young PR, Lanni C, Stewart AO, Bouska J, Malo PE, Carter GW.
    J Lipid Mediat; 1993 Jun 19; 6(1-3):259-64. PubMed ID: 8395248
    [Abstract] [Full Text] [Related]

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  • 11. 2-substituted indazolinones: orally active and selective 5-lipoxygenase inhibitors with anti-inflammatory activity.
    Foster SJ, Bruneau P, Walker ER, McMillan RM.
    Br J Pharmacol; 1990 Jan 19; 99(1):113-8. PubMed ID: 2110012
    [Abstract] [Full Text] [Related]

  • 12. Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivo.
    Tateson JE, Randall RW, Reynolds CH, Jackson WP, Bhattacherjee P, Salmon JA, Garland LG.
    Br J Pharmacol; 1988 Jun 19; 94(2):528-39. PubMed ID: 2840160
    [Abstract] [Full Text] [Related]

  • 13.
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  • 14. Effect of Zileuton (A-64077) on the 5-lipoxygenase activity of human whole blood ex vivo.
    Sirois P, Borgeat P, Lauzière M, Dubé L, Rubin P, Kesterson J.
    Agents Actions; 1991 Sep 19; 34(1-2):117-20. PubMed ID: 1665285
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of leukotriene biosynthesis in the rat peritoneal cavity.
    Young PR, Bell RL, Lanni C, Summers JB, Brooks DW, Carter GW.
    Eur J Pharmacol; 1991 Dec 03; 205(3):259-66. PubMed ID: 1817962
    [Abstract] [Full Text] [Related]

  • 16. Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.
    Ku EC, Raychaudhuri A, Ghai G, Kimble EF, Lee WH, Colombo C, Dotson R, Oglesby TD, Wasley JW.
    Biochim Biophys Acta; 1988 Apr 15; 959(3):332-42. PubMed ID: 2833314
    [Abstract] [Full Text] [Related]

  • 17. L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor.
    Gillard J, Ford-Hutchinson AW, Chan C, Charleson S, Denis D, Foster A, Fortin R, Leger S, McFarlane CS, Morton H.
    Can J Physiol Pharmacol; 1989 May 15; 67(5):456-64. PubMed ID: 2548691
    [Abstract] [Full Text] [Related]

  • 18. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation.
    Kirchner T, Argentieri DC, Barbone AG, Singer M, Steber M, Ansell J, Beers SA, Wachter MP, Wu W, Malloy E, Stewart A, Ritchie DM.
    J Pharmacol Exp Ther; 1997 Aug 15; 282(2):1094-101. PubMed ID: 9262379
    [Abstract] [Full Text] [Related]

  • 19. In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
    Oketani K, Nagakura N, Harada K, Inoue T.
    Eur J Pharmacol; 2001 Jun 22; 422(1-3):209-16. PubMed ID: 11430933
    [Abstract] [Full Text] [Related]

  • 20. A rat air pouch model for evaluating the efficacy and selectivity of 5-lipoxygenase inhibitors.
    Zweifel BS, Hardy MM, Anderson GD, Dufield DR, Pufahl RA, Masferrer JL.
    Eur J Pharmacol; 2008 Apr 14; 584(1):166-74. PubMed ID: 18295198
    [Abstract] [Full Text] [Related]

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