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Journal Abstract Search

236 related items for PubMed ID: 18495479

  • 1. Structure-based optimization of a potent class of arylamide FMS inhibitors.
    Meegalla SK, Wall MJ, Chen J, Wilson KJ, Ballentine SK, Desjarlais RL, Schubert C, Crysler CS, Chen Y, Molloy CJ, Chaikin MA, Manthey CL, Player MR, Tomczuk BE, Illig CR.
    Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3632-7. PubMed ID: 18495479
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  • 2. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents.
    Illig CR, Chen J, Wall MJ, Wilson KJ, Ballentine SK, Rudolph MJ, DesJarlais RL, Chen Y, Schubert C, Petrounia I, Crysler CS, Molloy CJ, Chaikin MA, Manthey CL, Player MR, Tomczuk BE, Meegalla SK.
    Bioorg Med Chem Lett; 2008 Mar 01; 18(5):1642-8. PubMed ID: 18242992
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  • 3. Potent 2'-aminoanilide inhibitors of cFMS as potential anti-inflammatory agents.
    Patch RJ, Brandt BM, Asgari D, Baindur N, Chadha NK, Georgiadis T, Cheung WS, Petrounia IP, Donatelli RR, Chaikin MA, Player MR.
    Bioorg Med Chem Lett; 2007 Nov 15; 17(22):6070-4. PubMed ID: 17904845
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  • 4. Discovery of 2-(alpha-methylbenzylamino) pyrazines as potent Type II inhibitors of FMS.
    Burns CJ, Harte MF, Bu X, Fantino E, Giarrusso M, Joffe M, Kurek M, Legge FS, Razzino P, Su S, Treutlein H, Wan SS, Zeng J, Wilks AF.
    Bioorg Med Chem Lett; 2009 Feb 15; 19(4):1206-9. PubMed ID: 19128971
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  • 8. Pyrido[2,3-d]pyrimidin-5-ones: a novel class of antiinflammatory macrophage colony-stimulating factor-1 receptor inhibitors.
    Huang H, Hutta DA, Rinker JM, Hu H, Parsons WH, Schubert C, DesJarlais RL, Crysler CS, Chaikin MA, Donatelli RR, Chen Y, Cheng D, Zhou Z, Yurkow E, Manthey CL, Player MR.
    J Med Chem; 2009 Feb 26; 52(4):1081-99. PubMed ID: 19193011
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  • 11. 'Reverse' alpha-ketoamide-based p38 MAP kinase inhibitors.
    Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, Roberts E, Saiah E, Sullivan R, Wang Z, Larson CJ.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5456-9. PubMed ID: 18835164
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  • 14. Structure-based design and optimization of potent renin inhibitors on 5- or 7-azaindole-scaffolds.
    Matter H, Scheiper B, Steinhagen H, Böcskei Z, Fleury V, McCort G.
    Bioorg Med Chem Lett; 2011 Sep 15; 21(18):5487-92. PubMed ID: 21840215
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  • 17. Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors.
    Illig CR, Manthey CL, Meegalla SK, Wall MJ, Chen J, Wilson KJ, DesJarlais RL, Ballentine SK, Schubert C, Crysler CS, Chen Y, Molloy CJ, Chaikin MA, Donatelli RR, Yurkow E, Zhou Z, Player MR, Tomczuk BE.
    Bioorg Med Chem Lett; 2013 Dec 01; 23(23):6363-9. PubMed ID: 24138939
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  • 18. Design of bivalent ligands using hydrogen bond linkers: synthesis and evaluation of inhibitors for human beta-tryptase.
    Vaz RJ, Gao Z, Pribish J, Chen X, Levell J, Davis L, Albert E, Brollo M, Ugolini A, Cramer DM, Cairns J, Sides K, Liu F, Kwong J, Kang J, Rebello S, Elliot M, Lim H, Chellaraj V, Singleton RW, Li Y.
    Bioorg Med Chem Lett; 2004 Dec 20; 14(24):6053-6. PubMed ID: 15546728
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