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157 related items for PubMed ID: 18498253
1. Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila. Bebrone C, Anne C, Kerff F, Garau G, De Vriendt K, Lantin R, Devreese B, Van Beeumen J, Dideberg O, Frère JM, Galleni M. Biochem J; 2008 Aug 15; 414(1):151-9. PubMed ID: 18498253 [Abstract] [Full Text] [Related]
2. A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. Garau G, Bebrone C, Anne C, Galleni M, Frère JM, Dideberg O. J Mol Biol; 2005 Jan 28; 345(4):785-95. PubMed ID: 15588826 [Abstract] [Full Text] [Related]
3. Dramatic broadening of the substrate profile of the Aeromonas hydrophila CphA metallo-beta-lactamase by site-directed mutagenesis. Bebrone C, Anne C, De Vriendt K, Devreese B, Rossolini GM, Van Beeumen J, Frère JM, Galleni M. J Biol Chem; 2005 Aug 05; 280(31):28195-202. PubMed ID: 15863831 [Abstract] [Full Text] [Related]
4. The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site. Bebrone C, Delbrück H, Kupper MB, Schlömer P, Willmann C, Frère JM, Fischer R, Galleni M, Hoffmann KM. Antimicrob Agents Chemother; 2009 Oct 05; 53(10):4464-71. PubMed ID: 19651913 [Abstract] [Full Text] [Related]
7. Deep Sequencing of Random Mutant Libraries Reveals the Active Site of the Narrow Specificity CphA Metallo-β-Lactamase is Fragile to Mutations. Sun Z, Mehta SC, Adamski CJ, Gibbs RA, Palzkill T. Sci Rep; 2016 Sep 12; 6():33195. PubMed ID: 27616327 [Abstract] [Full Text] [Related]
10. High specificity of cphA-encoded metallo-beta-lactamase from Aeromonas hydrophila AE036 for carbapenems and its contribution to beta-lactam resistance. Segatore B, Massidda O, Satta G, Setacci D, Amicosante G. Antimicrob Agents Chemother; 1993 Jun 12; 37(6):1324-8. PubMed ID: 8328781 [Abstract] [Full Text] [Related]
11. Zn(II) dependence of the Aeromonas hydrophila AE036 metallo-beta-lactamase activity and stability. Hernandez Valladares M, Felici A, Weber G, Adolph HW, Zeppezauer M, Rossolini GM, Amicosante G, Frère JM, Galleni M. Biochemistry; 1997 Sep 23; 36(38):11534-41. PubMed ID: 9298974 [Abstract] [Full Text] [Related]