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Journal Abstract Search

329 related items for PubMed ID: 18499210

  • 1. Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.
    Nelson JD, Kinkead H, Brunel FM, Leaman D, Jensen R, Louis JM, Maruyama T, Bewley CA, Bowdish K, Clore GM, Dawson PE, Frederickson S, Mage RG, Richman DD, Burton DR, Zwick MB.
    Virology; 2008 Jul 20; 377(1):170-83. PubMed ID: 18499210
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  • 4. Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41.
    Gustchina E, Bewley CA, Clore GM.
    J Virol; 2008 Oct 20; 82(20):10032-41. PubMed ID: 18667502
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  • 8. Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp41 in the pre-hairpin and six-helix bundle conformations.
    Louis JM, Aniana A, Lohith K, Sayer JM, Roche J, Bewley CA, Clore GM.
    PLoS One; 2014 Oct 20; 9(8):e104683. PubMed ID: 25105806
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  • 10. The high-affinity immunoglobulin receptor FcγRI potentiates HIV-1 neutralization via antibodies against the gp41 N-heptad repeat.
    Montefiori DC, Filsinger Interrante MV, Bell BN, Rubio AA, Joyce JG, Shiver JW, LaBranche CC, Kim PS.
    Proc Natl Acad Sci U S A; 2021 Jan 19; 118(3):. PubMed ID: 33431684
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  • 11. Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41.
    Gustchina E, Li M, Louis JM, Anderson DE, Lloyd J, Frisch C, Bewley CA, Gustchina A, Wlodawer A, Clore GM.
    PLoS Pathog; 2010 Nov 11; 6(11):e1001182. PubMed ID: 21085615
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  • 13. The Tryptophan-Rich Motif of HIV-1 gp41 Can Interact with the N-Terminal Deep Pocket Site: New Insights into the Structure and Function of gp41 and Its Inhibitors.
    Zhu Y, Ding X, Yu D, Chong H, He Y.
    J Virol; 2019 Dec 12; 94(1):. PubMed ID: 31619552
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  • 14. Identification of HIV gp41-specific antibodies that mediate killing of infected cells.
    Williams KL, Stumpf M, Naiman NE, Ding S, Garrett M, Gobillot T, Vézina D, Dusenbury K, Ramadoss NS, Basom R, Kim PS, Finzi A, Overbaugh J.
    PLoS Pathog; 2019 Feb 12; 15(2):e1007572. PubMed ID: 30779811
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  • 15. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.
    Zwick MB, Labrijn AF, Wang M, Spenlehauer C, Saphire EO, Binley JM, Moore JP, Stiegler G, Katinger H, Burton DR, Parren PW.
    J Virol; 2001 Nov 12; 75(22):10892-905. PubMed ID: 11602729
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  • 16. Monoclonal Antibody 2C6 Targets a Cross-Clade Conformational Epitope in gp41 with Highly Active Antibody-Dependent Cell Cytotoxicity.
    Sojar H, Baron S, Sullivan JT, Garrett M, van Haaren MM, Hoffman J, Overbaugh J, Doranz BJ, Hicar MD.
    J Virol; 2019 Sep 01; 93(17):. PubMed ID: 31217246
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  • 17. Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion.
    Louis JM, Nesheiwat I, Chang L, Clore GM, Bewley CA.
    J Biol Chem; 2003 May 30; 278(22):20278-85. PubMed ID: 12654905
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  • 18. Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 with potential as anti-HIV-1 drugs.
    Crespillo S, Cámara-Artigas A, Casares S, Morel B, Cobos ES, Mateo PL, Mouz N, Martin CE, Roger MG, El Habib R, Su B, Moog C, Conejero-Lara F.
    Proc Natl Acad Sci U S A; 2014 Dec 23; 111(51):18207-12. PubMed ID: 25489108
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  • 19. Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.
    Zhang MY, Vu BK, Choudhary A, Lu H, Humbert M, Ong H, Alam M, Ruprecht RM, Quinnan G, Jiang S, Montefiori DC, Mascola JR, Broder CC, Haynes BF, Dimitrov DS.
    J Virol; 2008 Jul 23; 82(14):6869-79. PubMed ID: 18480433
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  • 20. Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion.
    Finnegan CM, Berg W, Lewis GK, DeVico AL.
    J Virol; 2002 Dec 23; 76(23):12123-34. PubMed ID: 12414953
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