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Journal Abstract Search


231 related items for PubMed ID: 18504316

  • 1. MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: auxiliary subunits that enable channel activity.
    Brown AL, Liao Z, Goodman MB.
    J Gen Physiol; 2008 Jun; 131(6):605-16. PubMed ID: 18504316
    [Abstract] [Full Text] [Related]

  • 2. Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade.
    Brown AL, Fernandez-Illescas SM, Liao Z, Goodman MB.
    J Gen Physiol; 2007 Feb; 129(2):161-73. PubMed ID: 17261841
    [Abstract] [Full Text] [Related]

  • 3. The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel.
    Chelur DS, Ernstrom GG, Goodman MB, Yao CA, Chen L, O' Hagan R, Chalfie M.
    Nature; 2002 Dec 12; 420(6916):669-73. PubMed ID: 12478294
    [Abstract] [Full Text] [Related]

  • 4. Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.
    Chen Y, Bharill S, Isacoff EY, Chalfie M.
    Proc Natl Acad Sci U S A; 2015 Sep 15; 112(37):11690-5. PubMed ID: 26324944
    [Abstract] [Full Text] [Related]

  • 5. Intersubunit interactions between mutant DEG/ENaCs induce synthetic neurotoxicity.
    Zhang W, Bianchi L, Lee WH, Wang Y, Israel S, Driscoll M.
    Cell Death Differ; 2008 Nov 15; 15(11):1794-803. PubMed ID: 18670436
    [Abstract] [Full Text] [Related]

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  • 7. The DEG/ENaC protein MEC-10 regulates the transduction channel complex in Caenorhabditis elegans touch receptor neurons.
    Arnadóttir J, O'Hagan R, Chen Y, Goodman MB, Chalfie M.
    J Neurosci; 2011 Aug 31; 31(35):12695-704. PubMed ID: 21880930
    [Abstract] [Full Text] [Related]

  • 8. Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit.
    Shi S, Luke CJ, Miedel MT, Silverman GA, Kleyman TR.
    J Biol Chem; 2016 Jul 01; 291(27):14012-14022. PubMed ID: 27189943
    [Abstract] [Full Text] [Related]

  • 9. Pore-lining residues of MEC-4 and MEC-10 channel subunits tune the Caenorhabditis elegans degenerin channel's response to shear stress.
    Shi S, Mutchler SM, Blobner BM, Kashlan OB, Kleyman TR.
    J Biol Chem; 2018 Jul 06; 293(27):10757-10766. PubMed ID: 29743244
    [Abstract] [Full Text] [Related]

  • 10. The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals.
    O'Hagan R, Chalfie M, Goodman MB.
    Nat Neurosci; 2005 Jan 06; 8(1):43-50. PubMed ID: 15580270
    [Abstract] [Full Text] [Related]

  • 11. MEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.
    Chen Y, Bharill S, O'Hagan R, Isacoff EY, Chalfie M.
    G3 (Bethesda); 2016 Apr 07; 6(4):1121-30. PubMed ID: 27172609
    [Abstract] [Full Text] [Related]

  • 12. Regulation of the epithelial Na+ channel by paraoxonase-2.
    Shi S, Buck TM, Kinlough CL, Marciszyn AL, Hughey RP, Chalfie M, Brodsky JL, Kleyman TR.
    J Biol Chem; 2017 Sep 22; 292(38):15927-15938. PubMed ID: 28768768
    [Abstract] [Full Text] [Related]

  • 13. Caenorhabditis elegans paraoxonase-like proteins control the functional expression of DEG/ENaC mechanosensory proteins.
    Chen Y, Bharill S, Altun Z, O'Hagan R, Coblitz B, Isacoff EY, Chalfie M.
    Mol Biol Cell; 2016 Apr 15; 27(8):1272-85. PubMed ID: 26941331
    [Abstract] [Full Text] [Related]

  • 14. MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation.
    Goodman MB, Ernstrom GG, Chelur DS, O'Hagan R, Yao CA, Chalfie M.
    Nature; 2002 Feb 28; 415(6875):1039-42. PubMed ID: 11875573
    [Abstract] [Full Text] [Related]

  • 15. MEC-2 is recruited to the putative mechanosensory complex in C. elegans touch receptor neurons through its stomatin-like domain.
    Zhang S, Arnadottir J, Keller C, Caldwell GA, Yao CA, Chalfie M.
    Curr Biol; 2004 Nov 09; 14(21):1888-96. PubMed ID: 15530389
    [Abstract] [Full Text] [Related]

  • 16. Temperature-sensitive mutant of the Caenorhabditis elegans neurotoxic MEC-4(d) DEG/ENaC channel identifies a site required for trafficking or surface maintenance.
    Royal DC, Bianchi L, Royal MA, Lizzio M, Mukherjee G, Nunez YO, Driscoll M.
    J Biol Chem; 2005 Dec 23; 280(51):41976-86. PubMed ID: 16239217
    [Abstract] [Full Text] [Related]

  • 17. Touch sensitivity in Caenorhabditis elegans.
    Bounoutas A, Chalfie M.
    Pflugers Arch; 2007 Aug 23; 454(5):691-702. PubMed ID: 17285303
    [Abstract] [Full Text] [Related]

  • 18. Ca2+ permeability and Na+ conductance in cellular toxicity caused by hyperactive DEG/ENaC channels.
    Matthewman C, Miller-Fleming TW, Miller DM, Bianchi L.
    Am J Physiol Cell Physiol; 2016 Dec 01; 311(6):C920-C930. PubMed ID: 27760755
    [Abstract] [Full Text] [Related]

  • 19. A transmembrane domain of the putative channel subunit MEC-4 influences mechanotransduction and neurodegeneration in C. elegans.
    Hong K, Driscoll M.
    Nature; 1994 Feb 03; 367(6462):470-3. PubMed ID: 8107806
    [Abstract] [Full Text] [Related]

  • 20. Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel.
    Shi S, Montalbetti N, Wang X, Rush BM, Marciszyn AL, Baty CJ, Tan RJ, Carattino MD, Kleyman TR.
    J Biol Chem; 2020 Apr 10; 295(15):4950-4962. PubMed ID: 32079677
    [Abstract] [Full Text] [Related]


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