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Journal Abstract Search
367 related items for PubMed ID: 18506083
1. Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment. Takasawa K, Kubota N, Terauchi Y, Kadowaki T. Endocr J; 2008 Aug; 55(4):767-76. PubMed ID: 18506083 [Abstract] [Full Text] [Related]
2. Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling. Roh HC, Kumari M, Taleb S, Tenen D, Jacobs C, Lyubetskaya A, Tsai LT, Rosen ED. Mol Metab; 2020 Dec; 42():101086. PubMed ID: 32992037 [Abstract] [Full Text] [Related]
3. PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo. Kershaw EE, Schupp M, Guan HP, Gardner NP, Lazar MA, Flier JS. Am J Physiol Endocrinol Metab; 2007 Dec; 293(6):E1736-45. PubMed ID: 17848638 [Abstract] [Full Text] [Related]
4. Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination. Tsuchida A, Yamauchi T, Takekawa S, Hada Y, Ito Y, Maki T, Kadowaki T. Diabetes; 2005 Dec; 54(12):3358-70. PubMed ID: 16306350 [Abstract] [Full Text] [Related]
5. Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, Webster NJ, Schwartz MW, Olefsky JM. Nat Med; 2011 May; 17(5):618-22. PubMed ID: 21532596 [Abstract] [Full Text] [Related]
6. A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties. Fujimura T, Kimura C, Oe T, Takata Y, Sakuma H, Aramori I, Mutoh S. J Pharmacol Exp Ther; 2006 Aug; 318(2):863-71. PubMed ID: 16682454 [Abstract] [Full Text] [Related]
7. Cystathionine γ lyase-hydrogen sulfide increases peroxisome proliferator-activated receptor γ activity by sulfhydration at C139 site thereby promoting glucose uptake and lipid storage in adipocytes. Cai J, Shi X, Wang H, Fan J, Feng Y, Lin X, Yang J, Cui Q, Tang C, Xu G, Geng B. Biochim Biophys Acta; 2016 May; 1861(5):419-29. PubMed ID: 26946260 [Abstract] [Full Text] [Related]
8. Peroxisome Proliferator-Activated Receptor γ and Its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization. Wang QA, Zhang F, Jiang L, Ye R, An Y, Shao M, Tao C, Gupta RK, Scherer PE. Mol Cell Biol; 2018 May 15; 38(10):. PubMed ID: 29483301 [Abstract] [Full Text] [Related]
9. Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo. Nakano R, Kurosaki E, Yoshida S, Yokono M, Shimaya A, Maruyama T, Shibasaki M. Biochem Pharmacol; 2006 Jun 28; 72(1):42-52. PubMed ID: 16696951 [Abstract] [Full Text] [Related]
10. CMHX008, a novel peroxisome proliferator-activated receptor γ partial agonist, enhances insulin sensitivity in vitro and in vivo. Ming Y, Hu X, Song Y, Liu Z, Li J, Gao R, Zhang Y, Mei H, Guo T, Xiao L, Wang B, Wu C, Xiao X. PLoS One; 2014 Jun 28; 9(7):e102102. PubMed ID: 25004107 [Abstract] [Full Text] [Related]
11. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A. Diabetes; 2008 Aug 28; 57(8):1999-2011. PubMed ID: 18458147 [Abstract] [Full Text] [Related]
12. The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo. Li YY, Wu HS, Tang L, Feng CR, Yu JH, Li Y, Yang YS, Yang B, He QJ. Pharmacol Res; 2007 Oct 28; 56(4):335-43. PubMed ID: 17889553 [Abstract] [Full Text] [Related]
13. A Novel Peroxisome Proliferator-activated Receptor (PPAR)α Agonist and PPARγ Antagonist, Z-551, Ameliorates High-fat Diet-induced Obesity and Metabolic Disorders in Mice. Shiomi Y, Yamauchi T, Iwabu M, Okada-Iwabu M, Nakayama R, Orikawa Y, Yoshioka Y, Tanaka K, Ueki K, Kadowaki T. J Biol Chem; 2015 Jun 05; 290(23):14567-81. PubMed ID: 25907553 [Abstract] [Full Text] [Related]
14. FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone. Stechschulte LA, Qiu B, Warrier M, Hinds TD, Zhang M, Gu H, Xu Y, Khuder SS, Russo L, Najjar SM, Lecka-Czernik B, Yong W, Sanchez ER. Endocrinology; 2016 Oct 05; 157(10):3888-3900. PubMed ID: 27442117 [Abstract] [Full Text] [Related]
15. PPAR agonist-induced reduction of Mcp1 in atherosclerotic plaques of obese, insulin-resistant mice depends on adiponectin-induced Irak3 expression. Hulsmans M, Geeraert B, Arnould T, Tsatsanis C, Holvoet P. PLoS One; 2013 Oct 05; 8(4):e62253. PubMed ID: 23620818 [Abstract] [Full Text] [Related]
16. Nuclear receptors as targets for drug development: molecular mechanisms for regulation of obesity and insulin resistance by peroxisome proliferator-activated receptor gamma, CREB-binding protein, and adiponectin. Tsuchida A, Yamauchi T, Kadowaki T. J Pharmacol Sci; 2005 Feb 05; 97(2):164-70. PubMed ID: 15725703 [Abstract] [Full Text] [Related]
17. Disruption of inducible 6-phosphofructo-2-kinase impairs the suppressive effect of PPARγ activation on diet-induced intestine inflammatory response. Guo X, Li H, Xu H, Halim V, Thomas LN, Woo SL, Huo Y, Chen YE, Sturino JM, Wu C. J Nutr Biochem; 2013 May 05; 24(5):770-5. PubMed ID: 22841546 [Abstract] [Full Text] [Related]
18. Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation. Haas B, Hass MDS, Voltz A, Vogel M, Walther J, Biswas A, Hass D, Pfeifer A. Mol Metab; 2024 Jul 05; 85():101956. PubMed ID: 38735390 [Abstract] [Full Text] [Related]
19. HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ. Zhang X, Chen X, Qi T, Kong Q, Cheng H, Cao X, Li Y, Li C, Liu L, Ding Z. Cell Death Differ; 2019 Nov 05; 26(11):2253-2267. PubMed ID: 30742088 [Abstract] [Full Text] [Related]
20. Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma. Risérus U, Tan GD, Fielding BA, Neville MJ, Currie J, Savage DB, Chatterjee VK, Frayn KN, O'Rahilly S, Karpe F. Diabetes; 2005 May 05; 54(5):1379-84. PubMed ID: 15855323 [Abstract] [Full Text] [Related] Page: [Next] [New Search]