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152 related items for PubMed ID: 1851154

  • 1. 5-Phosphoribosyl 1-pyrophosphate synthetase converts the acyclic nucleoside phosphonates 9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 9-(2-phosphonylmethoxyethyl)adenine directly to their antivirally active diphosphate derivatives.
    Balzarini J, De Clercq E.
    J Biol Chem; 1991 May 15; 266(14):8686-9. PubMed ID: 1851154
    [Abstract] [Full Text] [Related]

  • 2. Conversion of acyclic nucleoside phosphonates to their diphosphate derivatives by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.
    Balzarini J, De Clercq E.
    Adv Exp Med Biol; 1991 May 15; 309A():29-32. PubMed ID: 1665008
    [No Abstract] [Full Text] [Related]

  • 3. Metabolic diversity and antiviral activities of acyclic nucleoside phosphonates.
    Aduma P, Connelly MC, Srinivas RV, Fridland A.
    Mol Pharmacol; 1995 Apr 15; 47(4):816-22. PubMed ID: 7723743
    [Abstract] [Full Text] [Related]

  • 4. Phosphorylation of acyclic nucleotide analogs HPMPA and PMEA in L1210 mouse leukemia cell extracts.
    Merta A, Veselý J, Votruba I, Rosenberg I, Holý A.
    Neoplasma; 1990 Apr 15; 37(2):111-20. PubMed ID: 2160620
    [Abstract] [Full Text] [Related]

  • 5. Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound.
    Balzarini J, Hao Z, Herdewijn P, Johns DG, De Clercq E.
    Proc Natl Acad Sci U S A; 1991 Feb 15; 88(4):1499-503. PubMed ID: 1705039
    [Abstract] [Full Text] [Related]

  • 6. Acyclic adenine nucleoside phosphonates in plasma determined by high-performance liquid chromatography with fluorescence detection.
    Naesens L, Balzarini J, De Clercq E.
    Clin Chem; 1992 Apr 15; 38(4):480-5. PubMed ID: 1568310
    [Abstract] [Full Text] [Related]

  • 7. A human T lymphoid cell variant resistant to the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxyethyl)adenine shows a unique combination of a phosphorylation defect and increased efflux of the agent.
    Robbins BL, Connelly MC, Marshall DR, Srinivas RV, Fridland A.
    Mol Pharmacol; 1995 Feb 15; 47(2):391-7. PubMed ID: 7870049
    [Abstract] [Full Text] [Related]

  • 8. Phosphonylmethyl ethers of acyclic nucleoside analogues: inhibitors of HSV-1 induced ribonucleotide reductase.
    Cerný J, Votruba I, Vonka V, Rosenberg I, Otmar M, Holý A.
    Antiviral Res; 1990 May 15; 13(5):253-64. PubMed ID: 2168691
    [Abstract] [Full Text] [Related]

  • 9. Acyclic nucleotide analogues: synthesis, antiviral activity and inhibitory effects on some cellular and virus-encoded enzymes in vitro.
    Holý A, Votruba I, Merta A, Cerný J, Veselý J, Vlach J, Sedivá K, Rosenberg I, Otmar M, Hrebabecký H.
    Antiviral Res; 1990 Jun 15; 13(6):295-311. PubMed ID: 1699493
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates.
    Smeijsters LJ, Franssen FF, Naesens L, de Vries E, Holý A, Balzarini J, de Clercq E, Overdulve JP.
    Int J Antimicrob Agents; 1999 Jun 15; 12(1):53-61. PubMed ID: 10389648
    [Abstract] [Full Text] [Related]

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  • 13. Metabolism and in vitro antiretroviral activities of bis(pivaloyloxymethyl) prodrugs of acyclic nucleoside phosphonates.
    Srinivas RV, Robbins BL, Connelly MC, Gong YF, Bischofberger N, Fridland A.
    Antimicrob Agents Chemother; 1993 Oct 15; 37(10):2247-50. PubMed ID: 8257154
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  • 15. Phosphorylation of 9-(2-phosphonomethoxyethyl)adenine and 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine by AMP(dAMP) kinase from L1210 cells.
    Merta A, Votruba I, Jindrich J, Holý A, Cihlár T, Rosenberg I, Otmar M, Herve TY.
    Biochem Pharmacol; 1992 Nov 17; 44(10):2067-77. PubMed ID: 1449524
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  • 17. Coordination Chemistry of Nucleotides and Antivirally Active Acyclic Nucleoside Phosphonates, including Mechanistic Considerations.
    Sigel A, Sigel H, Sigel RKO.
    Molecules; 2022 Apr 19; 27(9):. PubMed ID: 35565975
    [Abstract] [Full Text] [Related]

  • 18. Novel acyclic adenosine analogs inhibit Epstein-Barr virus replication.
    Lin JC, DeClercq E, Pagano JS.
    Antimicrob Agents Chemother; 1987 Sep 19; 31(9):1431-3. PubMed ID: 2823699
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses.
    Hakimelahi GH, Ly TW, Moosavi-Movahedi AA, Jain ML, Zakerinia M, Davari H, Mei HC, Sambaiah T, Moshfegh AA, Hakimelahi S.
    J Med Chem; 2001 Oct 25; 44(22):3710-20. PubMed ID: 11606136
    [Abstract] [Full Text] [Related]

  • 20. Antiretroviral activities of acyclic nucleoside phosphonates [9-(2-phosphonylmethoxyethyl)adenine, 9-(2-phosphonylmethoxyethyl)guanine, (R)-9-(2-phosphonylmethoxypropyl)adenine, and MDL 74,968] in cell cultures and murine sarcoma virus-infected newborn NMRI mice.
    Balzarini J, Vahlenkamp T, Egberink H, Hartmann K, Witvrouw M, Pannecouque C, Casara P, Navé JF, De Clercq E.
    Antimicrob Agents Chemother; 1997 Mar 25; 41(3):611-6. PubMed ID: 9056002
    [Abstract] [Full Text] [Related]

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