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286 related items for PubMed ID: 18514481
1. Real life juvenile toxicity case studies: the good, the bad and the ugly. De Schaepdrijver L, Rouan MC, Raoof A, Bailey GP, De Zwart L, Monbaliu J, Coogan TP, Lammens L, Coussement W. Reprod Toxicol; 2008 Sep; 26(1):54-5. PubMed ID: 18514481 [Abstract] [Full Text] [Related]
7. The value of juvenile animal studies "What have we learned from preclinical juvenile toxicity studies? II". Bailey GP, Mariën D. Birth Defects Res B Dev Reprod Toxicol; 2011 Aug; 92(4):273-91. PubMed ID: 22623019 [Abstract] [Full Text] [Related]
9. Improving toxicity screening and drug development by using genetically defined strains. Festing MF. Methods Mol Biol; 2010 Aug; 602():1-21. PubMed ID: 20012389 [Abstract] [Full Text] [Related]
12. Juvenile toxicity: are we asking the right questions? Downes N. Toxicol Pathol; 2012 Jul; 40(5):830-7. PubMed ID: 22407308 [Abstract] [Full Text] [Related]
13. Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s. Powley MW, Frederick CB, Sistare FD, DeGeorge JJ. Chem Res Toxicol; 2009 Feb; 22(2):257-62. PubMed ID: 19170595 [Abstract] [Full Text] [Related]
14. Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection. Rhomberg LR, Baetcke K, Blancato J, Bus J, Cohen S, Conolly R, Dixit R, Doe J, Ekelman K, Fenner-Crisp P, Harvey P, Hattis D, Jacobs A, Jacobson-Kram D, Lewandowski T, Liteplo R, Pelkonen O, Rice J, Somers D, Turturro A, West W, Olin S. Crit Rev Toxicol; 2007 Feb; 37(9):729-837. PubMed ID: 17957539 [Abstract] [Full Text] [Related]
18. Safety evaluation to support First-In-Man investigations I: kinetic and safety pharmacology studies. Baldrick P. Regul Toxicol Pharmacol; 2008 Jul; 51(2):230-6. PubMed ID: 18501489 [Abstract] [Full Text] [Related]
19. Direct dosing of preweaning rodents in toxicity testing and research: deliberations of an ILSI RSI Expert Working Group. Moser VC, Walls I, Zoetis T. Int J Toxicol; 2005 Jul; 24(2):87-94. PubMed ID: 16036767 [Abstract] [Full Text] [Related]
20. Embryo-fetal developmental toxicity study design for pharmaceuticals. Wise LD, Buschmann J, Feuston MH, Fisher JE, Hew KW, Hoberman AM, Lerman SA, Ooshima Y, Stump DG. Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):418-28. PubMed ID: 20025038 [Abstract] [Full Text] [Related] Page: [Next] [New Search]