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Journal Abstract Search


286 related items for PubMed ID: 18514481

  • 1. Real life juvenile toxicity case studies: the good, the bad and the ugly.
    De Schaepdrijver L, Rouan MC, Raoof A, Bailey GP, De Zwart L, Monbaliu J, Coogan TP, Lammens L, Coussement W.
    Reprod Toxicol; 2008 Sep; 26(1):54-5. PubMed ID: 18514481
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  • 4. Juvenile animal toxicity study designs to support pediatric drug development.
    Cappon GD, Bailey GP, Buschmann J, Feuston MH, Fisher JE, Hew KW, Hoberman AM, Ooshima Y, Stump DG, Hurtt ME.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):463-9. PubMed ID: 20025047
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  • 5. Optimising the design of preliminary toxicity studies for pharmaceutical safety testing in the dog.
    Smith D, Combes R, Depelchin O, Jacobsen SD, Hack R, Luft J, Lammens L, von Landenberg F, Phillips B, Pfister R, Rabemampianina Y, Sparrow S, Stark C, Stephan-Gueldner M.
    Regul Toxicol Pharmacol; 2005 Mar; 41(2):95-101. PubMed ID: 15698532
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  • 7. The value of juvenile animal studies "What have we learned from preclinical juvenile toxicity studies? II".
    Bailey GP, Mariën D.
    Birth Defects Res B Dev Reprod Toxicol; 2011 Aug; 92(4):273-91. PubMed ID: 22623019
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  • 8. Preclinical evaluation of juvenile toxicity.
    Barrow PC, Barbellion S, Stadler J.
    Methods Mol Biol; 2011 Aug; 691():17-35. PubMed ID: 20972745
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  • 9. Improving toxicity screening and drug development by using genetically defined strains.
    Festing MF.
    Methods Mol Biol; 2010 Aug; 602():1-21. PubMed ID: 20012389
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  • 12. Juvenile toxicity: are we asking the right questions?
    Downes N.
    Toxicol Pathol; 2012 Jul; 40(5):830-7. PubMed ID: 22407308
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  • 13. Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s.
    Powley MW, Frederick CB, Sistare FD, DeGeorge JJ.
    Chem Res Toxicol; 2009 Feb; 22(2):257-62. PubMed ID: 19170595
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  • 14. Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.
    Rhomberg LR, Baetcke K, Blancato J, Bus J, Cohen S, Conolly R, Dixit R, Doe J, Ekelman K, Fenner-Crisp P, Harvey P, Hattis D, Jacobs A, Jacobson-Kram D, Lewandowski T, Liteplo R, Pelkonen O, Rice J, Somers D, Turturro A, West W, Olin S.
    Crit Rev Toxicol; 2007 Feb; 37(9):729-837. PubMed ID: 17957539
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  • 17. Non-clinical Post-Marketing Commitments for newly licenced pharmaceuticals.
    Reeve LM.
    Regul Toxicol Pharmacol; 2009 Nov; 55(2):181-7. PubMed ID: 19589365
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  • 18. Safety evaluation to support First-In-Man investigations I: kinetic and safety pharmacology studies.
    Baldrick P.
    Regul Toxicol Pharmacol; 2008 Jul; 51(2):230-6. PubMed ID: 18501489
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  • 19. Direct dosing of preweaning rodents in toxicity testing and research: deliberations of an ILSI RSI Expert Working Group.
    Moser VC, Walls I, Zoetis T.
    Int J Toxicol; 2005 Jul; 24(2):87-94. PubMed ID: 16036767
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  • 20. Embryo-fetal developmental toxicity study design for pharmaceuticals.
    Wise LD, Buschmann J, Feuston MH, Fisher JE, Hew KW, Hoberman AM, Lerman SA, Ooshima Y, Stump DG.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):418-28. PubMed ID: 20025038
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