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340 related items for PubMed ID: 18515579

  • 1. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
    Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, Girnita A, Girnita L, Axelson M, Seregard S, Larsson O.
    Invest Ophthalmol Vis Sci; 2008 Jun; 49(6):2337-42. PubMed ID: 18515579
    [Abstract] [Full Text] [Related]

  • 2. Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma.
    Economou MA, Andersson S, Vasilcanu D, All-Ericsson C, Menu E, Girnita A, Girnita L, Axelson M, Seregard S, Larsson O.
    Acta Ophthalmol; 2008 Nov; 86 Thesis 4():35-41. PubMed ID: 19032680
    [Abstract] [Full Text] [Related]

  • 3. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
    Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L.
    Clin Cancer Res; 2006 Feb 15; 12(4):1383-91. PubMed ID: 16489097
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  • 4. The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.
    Girnita A, All-Ericsson C, Economou MA, Aström K, Axelson M, Seregard S, Larsson O, Girnita L.
    Acta Ophthalmol; 2008 Nov 15; 86 Thesis 4():26-34. PubMed ID: 19032679
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
    Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, van der Ploeg I, Menu E, Girnita L, Axelson M, Larsson O, Seregard S, Kvanta A.
    Invest Ophthalmol Vis Sci; 2008 Jun 15; 49(6):2620-6. PubMed ID: 18515591
    [Abstract] [Full Text] [Related]

  • 6. Insulin-like growth factor-1 receptor in uveal melanoma: a predictor for metastatic disease and a potential therapeutic target.
    All-Ericsson C, Girnita L, Seregard S, Bartolazzi A, Jager MJ, Larsson O.
    Invest Ophthalmol Vis Sci; 2002 Jan 15; 43(1):1-8. PubMed ID: 11773005
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor.
    Economou MA, Wu J, Vasilcanu D, Rosengren L, All-Ericsson C, van der Ploeg I, Menu E, Girnita L, Axelson M, Larsson O, Seregard S, Kvanta A.
    Acta Ophthalmol; 2008 Nov 15; 86 Thesis 4():42-9. PubMed ID: 19032681
    [Abstract] [Full Text] [Related]

  • 8. Insulin-like growth factor type-I receptor-dependent phosphorylation of extracellular signal-regulated kinase 1/2 but not Akt (protein kinase B) can be induced by picropodophyllin.
    Vasilcanu R, Vasilcanu D, Sehat B, Yin S, Girnita A, Axelson M, Girnita L.
    Mol Pharmacol; 2008 Mar 15; 73(3):930-9. PubMed ID: 18070930
    [Abstract] [Full Text] [Related]

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  • 10. Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo.
    Tanno B, Mancini C, Vitali R, Mancuso M, McDowell HP, Dominici C, Raschellà G.
    Clin Cancer Res; 2006 Nov 15; 12(22):6772-80. PubMed ID: 17121898
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  • 12. Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications.
    Economou MA, All-Ericsson C, Bykov V, Girnita L, Bartolazzi A, Larsson O, Seregard S.
    Acta Ophthalmol; 2008 Nov 15; 86 Thesis 4():20-5. PubMed ID: 19032678
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  • 16. Correlation of clinicopathological parameters with HGF, c-Met, EGFR, and IGF-1R expression in uveal melanoma.
    Topcu-Yilmaz P, Kiratli H, Saglam A, Söylemezoglu F, Hascelik G.
    Melanoma Res; 2010 Apr 15; 20(2):126-32. PubMed ID: 20061986
    [Abstract] [Full Text] [Related]

  • 17. Picropodophyllin inhibits epithelial ovarian cancer cells in vitro and in vivo.
    Lu X, Wang L, Mei J, Wang X, Zhu X, Zhang Q, Lv J.
    Biochem Biophys Res Commun; 2013 Jun 07; 435(3):385-90. PubMed ID: 23665331
    [Abstract] [Full Text] [Related]

  • 18. R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts.
    Kolb EA, Kamara D, Zhang W, Lin J, Hingorani P, Baker L, Houghton P, Gorlick R.
    Pediatr Blood Cancer; 2010 Jul 15; 55(1):67-75. PubMed ID: 20486173
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