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Journal Abstract Search

237 related items for PubMed ID: 18516761

  • 1. Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.
    McCubrey JA, Milella M, Tafuri A, Martelli AM, Lunghi P, Bonati A, Cervello M, Lee JT, Steelman LS.
    Curr Opin Investig Drugs; 2008 Jun; 9(6):614-30. PubMed ID: 18516761
    [Abstract] [Full Text] [Related]

  • 2. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.
    Roberts PJ, Der CJ.
    Oncogene; 2007 May 14; 26(22):3291-310. PubMed ID: 17496923
    [Abstract] [Full Text] [Related]

  • 3. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
    Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, Wilhelm S, Lynch M, Carter C.
    Cancer Res; 2006 Dec 15; 66(24):11851-8. PubMed ID: 17178882
    [Abstract] [Full Text] [Related]

  • 4. Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy.
    Friday BB, Adjei AA.
    Clin Cancer Res; 2008 Jan 15; 14(2):342-6. PubMed ID: 18223206
    [Abstract] [Full Text] [Related]

  • 5. Emerging MEK inhibitors.
    McCubrey JA, Steelman LS, Abrams SL, Chappell WH, Russo S, Ove R, Milella M, Tafuri A, Lunghi P, Bonati A, Stivala F, Nicoletti F, Libra M, Martelli AM, Montalto G, Cervello M.
    Expert Opin Emerg Drugs; 2010 Jun 15; 15(2):203-23. PubMed ID: 20151845
    [Abstract] [Full Text] [Related]

  • 6. Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway.
    Gollob JA, Wilhelm S, Carter C, Kelley SL.
    Semin Oncol; 2006 Aug 15; 33(4):392-406. PubMed ID: 16890795
    [Abstract] [Full Text] [Related]

  • 7. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.
    J Pharmacol Exp Ther; 2009 Jun 15; 329(3):1063-70. PubMed ID: 19258520
    [Abstract] [Full Text] [Related]

  • 8. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R, Piperdi S, Gorlick R.
    Clin Cancer Res; 2008 Oct 15; 14(20):6396-404. PubMed ID: 18927278
    [Abstract] [Full Text] [Related]

  • 9. Targeting Raf/MEK/ERK pathway in pituitary adenomas.
    Suojun Z, Feng W, Dongsheng G, Ting L.
    Eur J Cancer; 2012 Feb 15; 48(3):389-95. PubMed ID: 22119203
    [Abstract] [Full Text] [Related]

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  • 11. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W.
    J Cell Physiol; 2009 Jul 15; 220(1):214-21. PubMed ID: 19288493
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  • 15. Combining chemo-, hormonal and targeted therapies to treat breast cancer (Review).
    Steelman LS, Navolanic PM, Franklin RA, Bonati A, Libra M, Stivala F, Martelli AM, McCubrey JA.
    Mol Med Rep; 2008 Jul 15; 1(2):139-60. PubMed ID: 21479390
    [Abstract] [Full Text] [Related]

  • 16. B-Raf kinase inhibitors for cancer treatment.
    Li N, Batt D, Warmuth M.
    Curr Opin Investig Drugs; 2007 Jun 15; 8(6):452-6. PubMed ID: 17621874
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  • 19. Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma.
    Panka DJ, Atkins MB, Mier JW.
    Clin Cancer Res; 2006 Apr 01; 12(7 Pt 2):2371s-2375s. PubMed ID: 16609061
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