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Journal Abstract Search

160 related items for PubMed ID: 18524582

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  • 3. Discovery of DPP IV inhibitors by pharmacophore modeling and QSAR analysis followed by in silico screening.
    Al-Masri IM, Mohammad MK, Taha MO.
    ChemMedChem; 2008 Nov; 3(11):1763-79. PubMed ID: 18989859
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  • 4. Synthesis, biological evaluation and structural determination of beta-aminoacyl-containing cyclic hydrazine derivatives as dipeptidyl peptidase IV (DPP-IV) inhibitors.
    Ahn JH, Shin MS, Jun MA, Jung SH, Kang SK, Kim KR, Rhee SD, Kang NS, Kim SY, Sohn SK, Kim SG, Jin MS, Lee JO, Cheon HG, Kim SS.
    Bioorg Med Chem Lett; 2007 May 01; 17(9):2622-8. PubMed ID: 17331715
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  • 5. Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin.
    Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE.
    Bioorg Med Chem Lett; 2007 Jun 15; 17(12):3384-7. PubMed ID: 17433672
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  • 6. Discovery of beta-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV.
    Nordhoff S, Cerezo-Gálvez S, Deppe H, Hill O, López-Canet M, Rummey C, Thiemann M, Matassa VG, Edwards PJ, Feurer A.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4201-3. PubMed ID: 19515557
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  • 12. Affinity-based ranking of ligands for DPP-4 from mixtures.
    Adam GC, Meng J, Athanasopoulos J, Zhang X, Chapman KT.
    Bioorg Med Chem Lett; 2007 May 01; 17(9):2404-7. PubMed ID: 17337342
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  • 14. 4-aminophenylalanine and 4-aminocyclohexylalanine derivatives as potent, selective, and orally bioavailable inhibitors of dipeptidyl peptidase IV.
    Duffy JL, Kirk BA, Wang L, Eiermann GJ, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Petrov A, Scapin G, Wu JK, Thornberry NA, Weber AE.
    Bioorg Med Chem Lett; 2007 May 15; 17(10):2879-85. PubMed ID: 17350841
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  • 17. The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity.
    Rigolet P, Xi XG, Rety S, Chich JF.
    FEBS J; 2005 Apr 15; 272(8):2050-9. PubMed ID: 15819895
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  • 18. Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog.
    Rasmussen HB, Branner S, Wiberg FC, Wagtmann N.
    Nat Struct Biol; 2003 Jan 15; 10(1):19-25. PubMed ID: 12483204
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  • 19. Design and synthesis of potent amido- and benzyl-substituted cis-3-amino-4-(2-cyanopyrrolidide)pyrrolidinyl DPP-IV inhibitors.
    Corbett JW, Dirico K, Song W, Boscoe BP, Doran SD, Boyer D, Qiu X, Ammirati M, Vanvolkenburg MA, McPherson RK, Parker JC, Cox ED.
    Bioorg Med Chem Lett; 2007 Dec 15; 17(24):6707-13. PubMed ID: 17977724
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  • 20. Identification of aminoethyl pyrrolo dihydroisoquinolinones as novel poly(ADP-ribose) polymerase-1 inhibitors.
    Branca D, Cerretani M, Jones P, Koch U, Orvieto F, Palumbi MC, Rowley M, Toniatti C, Muraglia E.
    Bioorg Med Chem Lett; 2009 Aug 01; 19(15):4042-5. PubMed ID: 19553107
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