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988 related items for PubMed ID: 18524889

  • 1. Erlotinib induces mitochondrial-mediated apoptosis in human H3255 non-small-cell lung cancer cells with epidermal growth factor receptorL858R mutation through mitochondrial oxidative phosphorylation-dependent activation of BAX and BAK.
    Ling YH, Lin R, Perez-Soler R.
    Mol Pharmacol; 2008 Sep; 74(3):793-806. PubMed ID: 18524889
    [Abstract] [Full Text] [Related]

  • 2. ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine.
    Seervi M, Rani A, Sharma AK, Santhosh Kumar TR.
    Biomed Pharmacother; 2018 Oct; 106():200-209. PubMed ID: 29960166
    [Abstract] [Full Text] [Related]

  • 3. Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.
    Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.
    J Biol Chem; 2006 Mar 17; 281(11):7049-59. PubMed ID: 16410245
    [Abstract] [Full Text] [Related]

  • 4. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 5. Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak.
    Tomiyama A, Serizawa S, Tachibana K, Sakurada K, Samejima H, Kuchino Y, Kitanaka C.
    J Natl Cancer Inst; 2006 Oct 18; 98(20):1462-73. PubMed ID: 17047195
    [Abstract] [Full Text] [Related]

  • 6. Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells.
    Kim MJ, Lee KH, Lee SJ.
    FEBS J; 2008 May 18; 275(9):2096-108. PubMed ID: 18373696
    [Abstract] [Full Text] [Related]

  • 7. Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.
    Mohan J, Gandhi AA, Bhavya BC, Rashmi R, Karunagaran D, Indu R, Santhoshkumar TR.
    J Biol Chem; 2006 Jun 30; 281(26):17599-611. PubMed ID: 16617056
    [Abstract] [Full Text] [Related]

  • 8. A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.
    de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, Ripoche H, Lazar V, Dessen P, Harper F, Pierron G, Pinna G, Araujo N, Harel-Belan A, Armand JP, Wong TW, Soria JC, Kroemer G.
    Cancer Res; 2007 Jul 01; 67(13):6253-62. PubMed ID: 17616683
    [Abstract] [Full Text] [Related]

  • 9. Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
    Gillissen B, Richter A, Richter A, Preissner R, Schulze-Osthoff K, Essmann F, Daniel PT.
    J Biol Chem; 2017 Apr 21; 292(16):6478-6492. PubMed ID: 28154184
    [Abstract] [Full Text] [Related]

  • 10. Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.
    Gómez-Benito M, Marzo I, Anel A, Naval J.
    Mol Pharmacol; 2005 Jun 21; 67(6):1991-8. PubMed ID: 15738311
    [Abstract] [Full Text] [Related]

  • 11. Apoptosis induction in prostate cancer cells and xenografts by combined treatment with Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand and CPT-11.
    Ray S, Almasan A.
    Cancer Res; 2003 Aug 01; 63(15):4713-23. PubMed ID: 12907654
    [Abstract] [Full Text] [Related]

  • 12. Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death.
    Wang J, Guo W, Zhou H, Luo N, Nie C, Zhao X, Yuan Z, Liu X, Wei Y.
    Oncotarget; 2015 Jul 10; 6(19):17192-205. PubMed ID: 25980443
    [Abstract] [Full Text] [Related]

  • 13. Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.
    Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N.
    Biochem Biophys Res Commun; 2016 Apr 29; 473(2):490-6. PubMed ID: 26996126
    [Abstract] [Full Text] [Related]

  • 14. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
    [Abstract] [Full Text] [Related]

  • 15. Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death.
    Kim MJ, Park MT, Yoon CH, Byun JY, Lee SJ.
    Biochem Biophys Res Commun; 2008 May 30; 370(2):353-8. PubMed ID: 18371298
    [Abstract] [Full Text] [Related]

  • 16. Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.
    Neise D, Graupner V, Gillissen BF, Daniel PT, Schulze-Osthoff K, Jänicke RU, Essmann F.
    Oncogene; 2008 Feb 28; 27(10):1387-96. PubMed ID: 17724463
    [Abstract] [Full Text] [Related]

  • 17. Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells.
    Zhang W, Wang X, Chen T.
    Cell Signal; 2012 May 28; 24(5):1037-46. PubMed ID: 22245142
    [Abstract] [Full Text] [Related]

  • 18. Indirect effects of Bax and Bak initiate the mitochondrial alterations that lead to cytochrome c release during arsenic trioxide-induced apoptosis.
    Nutt LK, Gogvadze V, Uthaisang W, Mirnikjoo B, McConkey DJ, Orrenius S.
    Cancer Biol Ther; 2005 Apr 28; 4(4):459-67. PubMed ID: 15846091
    [Abstract] [Full Text] [Related]

  • 19. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES, Park KJ, Choi HJ, Kim CH, Kim YS.
    Exp Cell Res; 2012 Aug 01; 318(13):1564-76. PubMed ID: 22513214
    [Abstract] [Full Text] [Related]

  • 20. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR, Jun do Y, Lee JY, Kim YH.
    Apoptosis; 2014 Jan 01; 19(1):224-40. PubMed ID: 24166139
    [Abstract] [Full Text] [Related]

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