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183 related items for PubMed ID: 18537208

  • 1. Effects of geometric isomerism and anions on the kinetics and mechanism of the stepwise formation of long-range DNA interstrand cross-links by dinuclear platinum antitumor complexes.
    Zhang J, Thomas DS, Berners-Price SJ, Farrell N.
    Chemistry; 2008; 14(21):6391-405. PubMed ID: 18537208
    [Abstract] [Full Text] [Related]

  • 2. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A, Berners-Price SJ, Davies MS, Thomas DS, Humphreys AS, Farrell N.
    J Am Chem Soc; 2004 Feb 25; 126(7):2166-80. PubMed ID: 14971952
    [Abstract] [Full Text] [Related]

  • 3. Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers.
    Cox JW, Berners-Price SJ, Davies MS, Qu Y, Farrell N.
    J Am Chem Soc; 2001 Feb 21; 123(7):1316-26. PubMed ID: 11456703
    [Abstract] [Full Text] [Related]

  • 4. Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.
    Ruhayel RA, Moniodis JJ, Yang X, Kasparkova J, Brabec V, Berners-Price SJ, Farrell NP.
    Chemistry; 2009 Sep 21; 15(37):9365-74. PubMed ID: 19691069
    [Abstract] [Full Text] [Related]

  • 5. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ, Davies MS, Cox JW, Thomas DS, Farrell N.
    Chemistry; 2003 Feb 03; 9(3):713-25. PubMed ID: 12569464
    [Abstract] [Full Text] [Related]

  • 6. Chimeric platinum-polyamines and DNA binding. Kinetics of DNA interstrand cross-link formation by dinuclear platinum complexes with polyamine linkers.
    Ruhayel RA, Langner JS, Oke MJ, Berners-Price SJ, Zgani I, Farrell NP.
    J Am Chem Soc; 2012 Apr 25; 134(16):7135-46. PubMed ID: 22443454
    [Abstract] [Full Text] [Related]

  • 7. Equilibrium and kinetic studies of the aquation of the dinuclear platinum complex [[trans-PtCl(NH3)2]2(mu-NH2(CH2)6NH2)]2+: pKa determinations of aqua ligands via [1H,15N] NMR spectroscopy.
    Davies MS, Cox JW, Berners-Price SJ, Barklage W, Qu Y, Farrell N.
    Inorg Chem; 2000 Apr 17; 39(8):1710-5. PubMed ID: 12526558
    [Abstract] [Full Text] [Related]

  • 8. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
    Brabec V, Kaspárková J, Vrána O, Nováková O, Cox JW, Qu Y, Farrell N.
    Biochemistry; 1999 May 25; 38(21):6781-90. PubMed ID: 10346899
    [Abstract] [Full Text] [Related]

  • 9. Competitive formation of DNA linkage isomers by a trinuclear platinum complex and the influence of pre-association.
    Moniodis JJ, Thomas DS, Davies MS, Berners-Price SJ, Farrell NP.
    Dalton Trans; 2015 Feb 28; 44(8):3583-3593. PubMed ID: 25407024
    [Abstract] [Full Text] [Related]

  • 10. Influence of geometric isomerism on the binding of platinum anticancer agents with phospholipids.
    Gorle AK, Zhang J, Berners-Price SJ, Farrell NP.
    Dalton Trans; 2019 Jul 02; 48(26):9791-9800. PubMed ID: 31070627
    [Abstract] [Full Text] [Related]

  • 11. Cooperative effects in long-range 1,4 DNA-DNA interstrand cross-links formed by polynuclear platinum complexes: an unexpected syn orientation of adenine bases outside the binding sites.
    Qu Y, Scarsdale NJ, Tran MC, Farrell NP.
    J Biol Inorg Chem; 2003 Jan 02; 8(1-2):19-28. PubMed ID: 12459895
    [Abstract] [Full Text] [Related]

  • 12. Structural consequences of a 3'-->3' DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex.
    Qu Y, Tran MC, Farrell NP.
    J Biol Inorg Chem; 2009 Aug 02; 14(6):969-77. PubMed ID: 19415349
    [Abstract] [Full Text] [Related]

  • 13. Effect of geometric isomerism in dinuclear platinum antitumor complexes on DNA interstrand cross-linking.
    Kaspárková J, Nováková O, Vrána O, Farrell N, Brabec V.
    Biochemistry; 1999 Aug 24; 38(34):10997-1005. PubMed ID: 10460154
    [Abstract] [Full Text] [Related]

  • 14. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.
    Kasparkova J, Vojtiskova M, Natile G, Brabec V.
    Chemistry; 2008 Aug 24; 14(4):1330-41. PubMed ID: 18022972
    [Abstract] [Full Text] [Related]

  • 15. Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes.
    Qu Y, Scarsdale NJ, Tran MC, Farrell N.
    J Inorg Biochem; 2004 Oct 24; 98(10):1585-90. PubMed ID: 15458820
    [Abstract] [Full Text] [Related]

  • 16. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies.
    Kaspárková J, Mellish KJ, Qu Y, Brabec V, Farrell N.
    Biochemistry; 1996 Dec 24; 35(51):16705-13. PubMed ID: 8988007
    [Abstract] [Full Text] [Related]

  • 17. Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
    Muchova T, Quintal SM, Farrell NP, Brabec V, Kasparkova J.
    J Biol Inorg Chem; 2012 Feb 24; 17(2):239-45. PubMed ID: 21938443
    [Abstract] [Full Text] [Related]

  • 18. Unique structural properties of DNA interstrand cross-links formed by a new antitumor dinuclear Pt(ii) complex.
    Hrabina O, Kasparkova J, Suchankova T, Novohradsky V, Guo Z, Brabec V.
    Metallomics; 2017 May 24; 9(5):494-500. PubMed ID: 28436510
    [Abstract] [Full Text] [Related]

  • 19. Structural Factors Affecting Binding of Platinum Anticancer Agents with Phospholipids: Influence of Charge and Phosphate Clamp Formation.
    Gorle AK, Zhang J, Liu Q, Berners-Price SJ, Farrell NP.
    Chemistry; 2018 Mar 26; 24(18):4643-4652. PubMed ID: 29341369
    [Abstract] [Full Text] [Related]

  • 20. Slowing of cisplatin aquation in the presence of DNA but not in the presence of phosphate: improved understanding of sequence selectivity and the roles of monoaquated and diaquated species in the binding of cisplatin to DNA.
    Davies MS, Berners-Price SJ, Hambley TW.
    Inorg Chem; 2000 Dec 11; 39(25):5603-13. PubMed ID: 11151361
    [Abstract] [Full Text] [Related]

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